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There are 3 main types of drug interactions to watch for: Drug-drug interactions: This is the most common type of drug interaction and involves one drug interacting with another. If you take many medicines, your chances for this type of interaction increases. Using Neurontin with other drugs that make you drowsy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, cold or allergy medicine, a muscle relaxer, or medicine for anxiety or seizures. Some of the main substances that interact with gabapentin are morphine, caffeine, losartan, ethacrynic acid, phenytoin, mefloquine and magnesium oxide. Some of the side effects caused by gabapentin are teratogenicity, hypoventilation, respiratory failure and myopathy. Gralise has different dosing requirements than other gabapentin medications and cannot be substituted. Horizant is specifically for restless legs syndrome and is usually taken around 5 PM. Swallow the tablets whole with food. Don't break, crush, or chew them. Don't switch Horizant with other Gabapentin medications. Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with gabapentin. There are 4 disease interactions with Neurontin (gabapentin). Major Potential Hazard, Moderate plausibility. Applicable conditions: Drug Abuse/Dependence. Anxiolytic, sedative, and hypnotic agents have the potential to cause dependence and abuse. Neurontin (gabapentin) is used to treat pain you may have from shingles (postherpetic nerve pain). It is also used with other seizure medicines for partial onset seizures in patients 3 years and older. Gralise (gabapentin) is only used for pain after having shingles (postherpetic nerve pain). It should not be used for any other medical condition. Some medicines may affect how gabapentin works or increase the chance of you having side effects. Antacids can reduce the amount of gabapentin that the body takes in so it does not work as well. To stop this happening, if you need to take an antacid, take it at least 2 hours before or after your dose of gabapentin. Does gabapentin interact with other medicines (drug interactions)? Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, Gabapentin is commonly prescribed with other medications. It is safe to take gabapentin with other medications, but understanding the possible drug interactions can help you live a healthier life. Gabapentin, also known by its brand name Neurontin, is a medication that has been used in the United States since the early 1990s. The drug helps Patients should be informed of the potentially fatal risks of interactions between gabapentin and alcohol, and with other medicines that cause CNS depression, particularly opioids. MHRA/CHM advice: Antiepileptic drugs in pregnancy: updated advice following comprehensive safety review (January 2021) See Epilepsy. Anxiolytic, sedative, and hypnotic agents have the potential to cause dependence and abuse. Tolerance as well as physical and psychological dependence can develop, particularly after prolonged use of excessive dosages, and abrupt cessation and/or a reduction in dosage may precipitate withdrawal symptoms. Gabapentin is a prescription drug most commonly prescribed to relieve nerve pain following shingles in adults and the pain of postherpetic neuralgia. Learn about side effects, drug interactions, dosages, warnings, and more. Gabapentin should not be mixed with any other illicit drugs, alcohol, or certain prescription medications like hydrocodone and morphine. If you’re considering taking an over-the-counter medication while on gabapentin, discuss it with your doctor before making a decision. Gabapentin is approved to prevent and control partial seizures, relieve postherpetic neuralgia after shingles and moderate-to-severe restless legs syndrome. Learn what side effects to watch for, drugs to avoid while taking gabapentin, how to take gabapentin and other important questions and answers. Are There Any Interactions Between Gabapentin and Other Medications? Yes, there are some medications that can interact with gabapentin and increase the risk of side effects. These include certain antibiotics, antifungal medications, and drugs used to treat seizures. Gabapentin, like any other substance, can interact with other substances.Those taking gabapentin should therefore always disclose to their doctors any medical conditions, other medications (prescription or over the counter), supplements, herbal products, illicit drugs, tobacco products, alcoholic beverages, and dietary choices. Taking gabapentin together with other medications can lead to drug interactions. Some of the drugs that can potentially interact with gabapentin include: Naproxen. Studies suggest that naproxen (aleve) increases the amount of gabapentin absorbed in the body.
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