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Expert-Led Spotlight Video Series Take your learning to the next level with these short lectures. Videos are typically less than 10 minutes and cover a variety of topics such as test utilization, testing technologies, new test explanations, and more. Test Name: NEURONTIN LEVEL General Information Lab Order Codes: NEUR Synonyms: Gabapentin CPT Codes: 80171 - Gabapentin Test Includes: Neurontin/Gabapentin concentration in ug/mL. Logistics Test Indications: Monitoring serum concentrations, assessing compliance, assessing signs of toxicity. Lab Testing Sections: Chemistry - Sendouts Gabapentin is cleared by the kidneys and has an elimination half-life of five to seven hours.1 Steady-state concentrations are reached after one to two days with the time between ingestion and maximal serum concentration being two to three hours.2 For therapeutic drug monitoring, specimens should be drawn as trough levels. Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC; 790394: Gabapentin, Urine: 790443: Gabapentin, Urine: ug/mL: 59680-9: Order Code gabapentin level, serum Welcome to the new Northwell Health Labs Test Directory, please call our Client Services Department at 1-800-472-5757 with any typos, corrections or issues. Gabapentin (Neurontin®) is an oral antiepileptic agent that is structurally related to the neurotransmitter γ-aminobutyric acid (GABA) but it does not interact with GABA receptors in the brain. Its mechanism of action is unknown but it has properties in common with other anticonvulsant medications. Gabapentin is not metabolized and depends on renal mechanisms for elimination. Changes in renal function, aging, and dialysis may necessitate dosage adjustment. Clinical Utility. Gabapentin is an antiepileptic drug. This assay is used to monitor the therapeutic drug level and evaluate the toxicity of gabapentin. CPT Codes. 80171 LOINC: 9738-6 Pharmacokinetics of gabapentin vary widely among patients, particularly those with compromised renal function. Adverse effects may include somnolence, dizziness, ataxia, and fatigue. Neurontin | 4032 | Gabapentin Level. Interface Order Alias. 10383. Quick Collect +S/PO/R. Collection Instructions. Test Frequency. Available 24 hours, usual TAT 1 Neurontin: PDM: 5901000: Informatics - Workgroup: Tox/TDM: Synonyms * ANTI-CONVULSANT NEURONTIN ANTIEPILEPTIC ANTI-EPILEPTIC AED DRUG ANTICONVULSANT: Display Name * Gabapentin level: Specimen Sources (combined Order Entry and Specimen Navigator) * Specimen Types (combined Order Entry and Specimen Navigator) * Gabapentin is an antiepileptic drug that is effective in treating seizures, neuropathies, and a variety of neurological and psychological maladies. Although designed as a gamma-aminobutyric acid (GABA) analogue, gabapentin does not bind to GABA receptors, nor does it affect the neuronal uptake or degradation of GABA. Gabapentin - Gabapentin is an anticonvulsant drug commonly used as adjunctive therapy to treat partial seizures. Therapeutic drug monitoring is useful to optimize dose and to avoid toxicity. Draw sample 2 hours after last dose. Chromatography/Mass Spectrometry. Gabapentin, Urine: 59680-9: Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories Gabapentin is an antiepileptic drug that is effective in treating seizures, neuropathies, and a variety of neurological and psychological maladies. Although designed as a gamma-aminobutyric acid (GABA) analogue, gabapentin does not bind to GABA receptors, nor does it affect the neuronal uptake or degradation of GABA. Home / Test / Gabapentin. Gabapentin Print Overview Specimen Clinical Overview Test Mnemonic. GABA. CPT Codes. 80171 - QTY (1) LOINC ® 9738-6. Aliases Drug Monitoring, Gabapentin, Quantitative, Urine - Gabapentin is used as an anticonvulsant in the management of neuropathic pain in adults and as adjunctive therapy in the treatment of partial seizures in patients with epilepsy. The test is a definitive assay using liquid chromatography mass spectroscopy (LC/MS/MS) methodology. Gabapentin is usually started low and titrated up to an effective dose. Below is the most common dosage for neuropathy: Initiate therapy at 300 mg PO as a single dose on day 1, then 600 mg/day (300 mg PO twice daily) on day 2, and 900 mg/day (300 mg PO three times per day) on day 3. Gabapentin is an antiepileptic drug effective as add-on therapy in treating complex partial seizures and partial seizures with secondary generalization. Gabapentin does not bind to serum proteins and does not exhibit pharmacokinetic interactions with other antiepileptic drugs. noassay, a qualitative test that screens for the five major drug classes targeted by federal workplace Level of misuse risk Frequency Low (no risk factors) Every 6 to 12 months Test Comments: The reference range is evolving. Seizure control has been observed at levels in excess of 4 mcg/mL. Methodology: Mass Spectrometry (MS) Clinical Significance. Gabatin is an anticonvulsant drug commonly used as adjunctive therapy to treat partial seizures. Therapeutic drug monitoring is useful to optimize dose and avoid toxicity.
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