Urinary Incontinence / chemically induced* gamma-Aminobutyric Acid / adverse effects* gamma-Aminobutyric Acid / therapeutic use symptoms: urinary urgency, with or without incontinence, and urinary frequency, often seri-ously compromising the quality of life of the people who have it. The complaint of these symptoms is defined by the International Con-tinence Society (www.continet. org) as ‘‘overac-tive bladder.’’ Many neurological patients The literature includes a few cases suggesting an association between gabapentin use and urinary incontinence. This case focuses on a previously unrecorded association between gabapentin and increased urinary frequency, which was dose dependent. Gabapentin (GBP) is a structural analog of gamma-aminobutyric acid (GABA) that is commonly used in palliative care for symptom management indications including neuropathic pain syndromes, hiccups, cough, and anxiety. An uncommon adverse effect of GBP is urinary incontinence (UI). These cases illustrates that gabapentin can cause both urinary and fecal incontinence. Gil-Nagel et al .,[ 2 ] hypothesized that incontinence was thought to be related to an effect of gabapentin in the cortex, interfering with the frontal lobe inhibition of the micturition center in the pons by modulation of neurotransmitters GABA and glutamate. Can Gabapentin Use Lead to Urinary Incontinence? - Prime MD Plus Gabapentin (GBP) is a structural analog of gamma-aminobutyric acid (GABA) that is commonly used in palliative care for symptom management indications including neuropathic pain syndromes, hiccups, cough, and anxiety. An uncommon adverse effect of GBP is urinary incontinence (UI). We report the case Physicians who administer gabapentin should inform their patients about the potential risk of gabapentin-induced incontinence and its negative impact on quality of life. Gabapentin is a first-line agent for neuropathic pain management and has a favorable safety profile. Gabapentin is a first-line agent for neuropathic pain management and has a favorable safety profile. The literature includes a few cases of gabapentin-induced incontinence, and most of them Yes, gabapentin can cause urinary incontinence, though it is considered a rare side effect. While the medication is primarily known for treating nerve pain, seizures, and restless legs syndrome, some individuals may experience a disruption in their bladder control while taking it. On the day following the cessation of gabapentin, the patient’s incontinence resolved. 3. Discussion. To the best of our knowledge, the literature includes just 5 cases of gabapentin-induced incontinence, 3 of which involved both rectal and urinary incontinence and 2 involved only urinary incontinence. In the following day, she complained of urinary incontinence with the absence of dysuria and urgency. It was not worse with movement, coughing, sneezing, or laughing. The vaginal parity of the patient was one. Laboratory tests and urinalysis were within normal limits. Some research points out that urinary incontinence can happen right after starting gabapentin. This is more common in people with neuropathic pain. Stopping gabapentin often helps fix this problem, showing the importance of watching for side effects. Gabapentin is a first-line agent for neuropathic pain management and has a favorable safety profile. The literature includes a few cases of gabapentin-induced incontinence, and most of them involved patients with epilepsy who were between the ages of 12 and 43 years. Fexofenadine and loratadine are both histamine 1 (H 1) receptor antagonists; the former is thought to cause urinary retention, which may in turn cause overflow incontinence, 15 while altered micturition, urinary retention and UI are reported as adverse events for loratadine at event rates <2%. 16 We were unable to find published case reports of Gabapentin was generally well tolerated and can be considered in selective patients when conventional modalities have failed. Urinary Incontinence / drug therapy*
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