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Among these, 4,642 (0.26%) were exposed to gabapentin during T1, 3,745 (0.21%) were exposed to gabapentin early in pregnancy only (during the first 140 days), 556 (0.03%) were exposed late in pregnancy but not early, and 1,275 (0.07%) were exposed in both early and late pregnancy . Gabapentin is a medication used to treat seizures, nerve pain, and restless legs syndrome. Learn about its effects on pregnancy, birth defects, miscarriage, breastfeeding, and more from this fact sheet by MotherToBaby. Learn about the reproductive safety of gabapentin, a medication used for various conditions, from a study and a review of the available data. The risk of major malformations is low, but there may be higher rates of preterm births and low birth weight. Gabapentin is an anti-seizure medication that may have risks for pregnancy. Learn about the mixed findings on its safety and how to talk to your doctor before taking it. Gabapentin is an antiepileptic drug used for various conditions, but its safety in pregnancy is unclear. A large study found no evidence of major malformations, but a slightly higher risk of cardiac defects and adverse outcomes in gabapentin-exposed infants. The objectives of our study were 3-fold: 1) to determine whether gabapentin exposure during pregnancy increases the rate of major malformations above the baseline population rate of 1% to 3%; 2) to examine the rates of stillbirths, spontaneous abortions, therapeutic abortions, gestational age at birth, and mean birth weight in exposed infants Pregnancy-related problems, such as preterm delivery (birth before week 37) or low birth weight (weighing less than 5 pounds, 8 ounces [2500 grams] at birth) have been reported in some studies looking at the use of gabapentin during pregnancy. Complications during pregnancy. While taking gabapentin during pregnancy can pose risks to the fetus, it is important to understand the potential complications that may arise during pregnancy. These complications can vary depending on the individual and their specific circumstances. Some potential complications that may occur include: Pregnant women and their physicians should weigh the benefits of treatment with gabapentin with the risks of potential adverse pregnancy outcomes associated with its use. Gabapentin is a gamma-aminobutyric acid (GABA) analog with GABA agonist activity. Despite the fact that gabapentin (Neurontin) is now used in a wide variety of clinical settings -- for epilepsy, pain management, anxiety, sleep disturbance – there is relatively little information regarding its reproductive safety. A prospective study from researchers at the Motherisk program reports on the outcomes of 223 pregnancies exposed to gabapentin and 223 unexposed pregnancies. This sheet is about exposure to gabapentin in pregnancy and while breastfeeding. This information is based on available published literature. It should not take the place of medical care and advice from your healthcare provider. What is gabapentin? Gabapentin is a medication that has been used to prevent and control partial seizures, treat some forms [] In pregnant women, a European study found that the prescribing of pregabalin and gabapentin during pregnancy has increased markedly in the United Kingdom from around 0.3 per 1000 in 2007 to 2.5–3.0 per 1000 in 2016, with about one-seventh of prescriptions likely intended for pain management [7]. A less pronounced increase was observed in Gabapentin (Neurontin) is an antiepileptic drug that may cause birth defects and harm the fetus. Learn about the risks, benefits, and alternatives of using gabapentin during pregnancy and breastfeeding. As a precaution, gabapentin is only prescribed in pregnancy when the benefits (most commonly of controlling seizures in women with epilepsy) outweigh the possible risks. Gabapentin is an anti-seizure drug and some of these can affect folic acid levels. Women taking gabapentin while trying to conceive and during pregnancy should therefore be Background: Despite the widespread use, only sparse information is available on the safety of gabapentin during pregnancy. We sought to evaluate the association between gabapentin exposure during pregnancy and risk of adverse neonatal and maternal outcomes. Gabapentin is not generally recommended in pregnancy as there is not enough information about its safety. It should only be taken if the benefits outweigh the risks. Learn about folic acid, withdrawal symptoms, and alternatives for epilepsy.
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