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Find information on Gabapentin (Gralise, Horizant) in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF. Antiseizure agents (also known as antiepileptic drugs or as anticonvulsants) are drugs used to manage epilepsy, the most prevalent neurological disorder. Antiseizure agents of choice depends on the type of epilepsy, age of the patient, patient tolerance, and specific patient characteristics. Table of Common Drugs and Generic Names Here is a table of commonly encountered antiseizure agents Gabapentin may cause suicidal thoughts, ataxia, or lack of muscle control and depression with these things in mind, monitor your patient for changes and behavior and depression while on Gabapentin, make sure you assess seizure activity and pain level in your patient, teach your patient to take this medication exactly as it's directed and to Read this chapter of Davis's Drug Guide for Rehabilitation Professionals online now, exclusively on F.A. Davis PT Collection. F.A. Davis PT Collection is a subscription-based resource from McGraw Hill that features trusted content from the best minds in PT. Understanding proper nursing considerations is crucial for safe and effective patient care. Generic name: Gabapentin. Brand names: Neurontin, Gralise, Horizant, Gabarone. Pharmacologic class: Anticonvulsant, Antiepileptic. Therapeutic class: Anticonvulsant, Analgesic for neuropathic pain. ANTIEPILEPTICS, PART 2: DRUG NAME: vigabatrin (Sabril) gabapentin (Neurontin, Gralise) CLASS: GABA inhibitors: GABA analogues: MECHANISM OF ACTION: Prevent GABA reuptake into presynaptic neurons; ↑ GABA concentration in synapse; ↓ seizure activity Gabapentin is used for partial seizures and neuropathic pain. Nursing Considerations Across the Lifespan. This drug can cause harm to the fetus of pregnant women. Gabapentin use in pediatric patients with epilepsy 3 to 12 years of age is associated with the occurrence of central nervous system related adverse events. Pain Management: Gabapentin Page 2 _____6. Which of the following patients is at highest risk for serious adverse effects of Neurontin: A. 32-year old nursing mother B. 60-year old woman with hypertension C. 75-year old man with emphysema D. 49-year old man who is immunocompromised _____7. Abrupt discontinuation of Neurontin is likely to cause: Nursing Considerations Therapeutic Effects Side/Adverse Effects; Anticonvulsant: gabapentin: Administer first dose at bedtime to decrease dizziness and drowsiness Monitor for worsening depression, suicidal thoughts or behavior, and/or any unusual changes in mood or behavior Taper dose; do not stop abruptly: Decreased neuropathic pain or seizures Gabapentin is structurally related to the neurotransmitter GABA but is neither a GABA agonist nor antagonist. Gabapentin-binding sites have been identified throughout the brain tissues e.g. neocortex and hippocampus. However, the exact mechanism of action is still unknown. Here are other nursing pharmacology study guides: Nursing Pharmacology – Study Guide for Nurses Our collection of topics related to nursing pharmacology; Pharmacology Nursing Mnemonics & Tips These nursing mnemonics aim to simplify the concepts of pharmacology through the use of a simple, concise guide. Generic Drug Name Stems Cheat Sheet Nursing implications When starting therapy or increasing the dosage, patients should be monitored for depression and suicidal thoughts. Assess the patient for fall risk secondary to fatigue and dizziness. Find information on Gabapentin (Gralise, Horizant) in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF. It is thought that Gabapentin may play a role in neural membranes. We use Gabapentin for the prevention of seizures for peripheral neuropathy, for neuropathic pain and for the prevention of migraines. In this article, you’ll learn about Gabapentin (Neurontin) nursing implications and patient teachings. Also, its dosage, indication, contraindications, interactions, side effects, nursing assessment, and nursing interventions. Nursing Implications Monitor of therapeutic effectiveness; may not occur until several weeks following initiation of therapy, in those treated for seizure disorders , assess frequency of seizures: In rare cases, the drug has increased the frequency of partial seizures, Monitor dizziness and CNS depression, monitor for changes in behavior that Nursing Implications: Monitor for possible suicidal ideation. Educate Patient on reporting changes in vision, hallucinations, and fever to their healthcare provider. Nursing Considerations for Gabapentin. When administering or caring for patients taking gabapentin, nurses should consider several important factors. Nursing Assessment. 1. Assess the patient’s medical history, including any known allergies, previous adverse reactions to gabapentin or similar medications, and relevant medical conditions. Mechanism of action: Gabapentin helps to stabilize cell membranes by changing cation (sodium, calcium, and potassium) transport, reducing excitability, and suppressing seizure focus or discharge. Indications for use: Adjunctive treatment for seizure control, postherpetic neuralgia, moderate to severe primary restless legs syndrome. Mechanism of action is not known. May affect transport of amino acids across and stabilize neuronal membranes. Decreased incidence of seizures. Contraindicated in: Hypersensitivity. Use Cautiously in: All patients (may ↑ risk of suicidal thoughts/behaviors); Renal insufficiency (↓ dose and/or ↑ dosing interval if CCr ≤60 mL/min);
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