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Pregnancy-related problems, such as preterm delivery (birth before week 37) or low birth weight (weighing less than 5 pounds, 8 ounces [2500 grams] at birth) have been reported in some studies looking at the use of gabapentin during pregnancy. While gabapentin is generally considered safe for use during pregnancy, there is limited research on its long-term effects on the developing fetus. Studies in animals have shown that gabapentin can cross the placenta and reach the fetus. These are not all the possible side effects of gabapentin. For more information, ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. How should I store gabapentin? Store gabapentin capsules and tablets at 20° to 25°C (68 to 77°F) Among these, 4,642 (0.26%) were exposed to gabapentin during T1, 3,745 (0.21%) were exposed to gabapentin early in pregnancy only (during the first 140 days), 556 (0.03%) were exposed late in pregnancy but not early, and 1,275 (0.07%) were exposed in both early and late pregnancy . Results from this large cohort study suggest that gabapentin exposure during early pregnancy does not appear to be associated with teratogenic effects, although a moderately higher risk of cardiac malformations—in particular, conotruncal defects—cannot be excluded. They can help monitor side effects and make adjustments to the treatment plan if needed. Common Side Effects. When taking Cymbalta, there are some common side effects that may occur. These can include nausea, dizziness, dry mouth, constipation, and fatigue. While these side effects are generally mild and temporary, it is important to be aware are pregnant or plan to become pregnant. are breastfeeding or plan to breastfeed. Gabapentin side effects. Gabapentin is approved by the FDA because it is safe and effective for the majority of people who take it. However, there are risks associated with all medicines. Some side effects caused by gabapentin can be very serious, and even life We examined the risk of major congenital malformations and cardiac defects associated with gabapentin exposure during the first trimester (T1), and the risk of preeclampsia (PE), preterm birth (PTB), small for gestational age (SGA), and neonatal intensive care unit admission (NICUa) associated with gabapentin exposure early, late, or both early If your physician believes that taking gabapentin while breastfeeding is more beneficial, be sure to monitor for possible side effects on your infant. Watch out for any signs of drowsiness, problems with feeding, and slow weight gain and development. Side Effects Common side effects of gabapentin. Gabapentin can cause several common side effects, including dizziness, drowsiness, and fatigue. Other commonly reported side effects include headache, nausea, and blurred vision. These side effects are usually mild and tend to improve over time as the body adjusts to the medication. Many people are afraid to take prescription medications while pregnant due to the risk of adverse effects on the developing fetus. But should you take gabapentin while pregnant? *Disclosure: Always consult a medical physician regarding any type of medication use while pregnant. Is Gabapentin Safe for Pregnant Women? This sheet is about exposure to gabapentin in pregnancy and while breastfeeding. This information is based on available published literature. It should not take the place of medical care and advice from your healthcare provider. What is gabapentin? Gabapentin is a medication that has been used to prevent and control partial seizures, treat some forms [] We have data on 223 pregnancy outcomes exposed to gabapentin and 223 unexposed pregnancies. The rates of major malformations were similar in both groups (p = 0.845). There was a higher rate of preterm births (p = 0.019) and low birth weight <2,500 g (p = 0.033) in the gabapentin group. Advice and warnings for the use of Gabapentin during pregnancy. FDA Pregnancy Category C - Risk cannot be ruled out There was an increased risk of preterm birth among women exposed to gabapentin either late (RR=1.28 [CI 1.08-1.52], p < 0.01) or both early and late in pregnancy (RR=1.22 [1.09-1.36], p < 0.001). It has not been known to cause any side effects in breastfed babies. If your baby is not feeding as well as usual, seems unusually sleepy, has a stomach upset, or if you have any other concerns about your baby, talk to your doctor, pharmacist, health visitor or midwife. Pregnancy-related problems, such as preterm delivery (birth before week 37) or low birth weight (weighing less than 5 pounds, 8 ounces [2500 grams] at birth) have been reported in some studies looking at the use of gabapentin during pregnancy. Research suggests that women who take gabapentin during pregnancy may have a higher likelihood of giving birth to babies with malformations, such as cleft lip, cleft palate, and heart defects. Gabapentin can cause side effects‚ such as dizziness‚ drowsiness‚ and nausea. Pregnant women⁚ Gabapentin should be used during pregnancy only if the
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