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Media Contact: LARA Communications 517-373-9280 Email: mediainfo@michigan.gov January 9, 2019 – In an effort to continue to combat the opioid epidemic in Michigan, the Dept. of Licensing and Regulatory Affairs (LARA), with the support of the Michigan Board of Pharmacy, has modified its Pharmacy Rules to categorize Gabapentin as a Schedule 5 controlled substance. For individuals applying for their initial controlled substance license, as well as those renewing their controlled substance license, rule changes made to R 338.3135 now require continued training in opioids and controlled substance awareness before applying for the initial license and each subsequent renewal of a controlled substance license. States are now taking action to track gabapentin use through prescription monitoring programs, and some states have reclassified it as a Schedule V controlled substance. This commentary summarizes gabapentin's abuse potential, identifies state-level actions regarding gabapentin monitoring, and discusses possible clinical implications and ways Classification of Gabapentin in Indiana. In Indiana, gabapentin’s classification has been scrutinized due to its misuse potential. Although not classified under the federal Controlled Substances Act, the Indiana Board of Pharmacy designated gabapentin as a “drug of concern” in 2019. Gabapentin is not currently listed as a controlled substance under the Controlled Substances Act of 1970. 11 Several state boards of pharmacy, as outlined in Supplemental Table 2 and Figure 1, have independently reclassified gabapentin under state pharmacy rules as a Schedule V drug. Other states have required gabapentin use to be monitored As of September 2022, gabapentin was classified as a controlled substance in Alabama, Kentucky, Michigan, North Dakota, Tennessee, Virginia, and West Virginia. 6,7 Adding gabapentin to the list of controlled substances has required providers to have a Drug Enforcement Administrationregistration number to prescribe it, adding another layer of single substance pharmaceutical exposures (i.e., the number of human exposure cases that identified only one substance), gabapentin was identified as a single substance in 6,955 cases in 2022. With respect to medical outcomes associated with gabapentin calls to poison control centers in 2022, gabapentin was associated with 6 deaths, 164 Kentucky last year became the first state to classify gabapentin as a controlled substance after the drug showed up in a third of the state’s fatal overdoses in 2016, as The Louisville Courier Gabapentin (Neurontin) is not a narcotic or federally controlled substance by the DEA as of November 2022, but it is classified as a Schedule V controlled substance in certain states. In general, medications classified as Schedule V (Schedule 5) controlled substances are considered to have the lowest potential for abuse compared to other , any new orders for Gabapentin issued by a practitioner WITHOUT a Utah. Controlled Substance license and a DEA registration will not be valid and MAY NOT be administered or dispensed. Prescription orders (including refills) issued for Gabapentin prior to May 1 , 2024, will not be. aected. It is not legal to distribute Gabapentin samples in Utah. prescription drug pursuant to Wis. Stat. § 961.385 (1) (ag). Gabapentin is now listed in Wis. Admin. Code § CSB 4.03 (2) as a monitored prescription drug effective September 1, 2021. Gabapentin Has Not Been Scheduled as a Controlled Substance Gabapentin has been designated as a monitored prescription drug, not a controlled substance. A DEA Schedule-V controlled substance and mandated reporting to PDMP. The State of Kentucky is, and to date, remains, the only state to have reclassified gabapentin as a Schedule-V controlled substance. 21 Effective July 1, 2017, the prescribing of gabapentin is limited to authorized practitioners, defined as practitioners registered with the US DEA. 21 Thus, mid-level practitioners, specifically NY A10321 - Classifies gabapentin as a controlled substance. AN ACT to amend the public health law, in relation to establishing a schedule VI of drugs and other substances, to including gabapentin as a drug to be monitored through the prescription monitoring program, and to make conforming changes; and to direct the commissioner of health to promulgate regulations necessary or desirable to FAQ’s Gabapentin Reporting for Animal Shelters and Rescues ; S.L. 2023-65 amends GS 90-106 . Requires a practitioner to electronically prescribe all controlled substances in GS 90-93(a)(1)a (not more than 200 milligrams of codeine or any of its salts per 100 milliliters or per 100 grams) effective January 1, 2024. Resources In 2019, the UK announced it would reclassify both pregabalin and gabapentin as class C controlled substances because of the rising numbers of deaths linked to the drugs. Gabapentin is not a controlled substance under the federal Controlled Substances Act. [125] Effective 1 July 2017, Kentucky classified gabapentin as a schedule V controlled substance statewide. [126] Gabapentin is scheduled V drug in other states such as West Virginia, [127] Tennessee, [128] Alabama, [129] Utah, [130] and Virginia. [131] Gabapentin isn’t a narcotic or federally controlled substance, but it is regulated and recognized as a controlled substance in certain states. Gabapentin’s unscheduled status reflects its lower potential for abuse or dependency compared to controlled substances. However, the FDA monitors gabapentin for potential misuse, particularly when combined with other central nervous system depressants. This oversight aims to balance its therapeutic benefits against abuse risks. Regional Variation Gabapentin is frequently combined with other substances for the purpose of potentiating the effects of the drugs or achieving a “high.” Studies have identified various substances that are commonly abused in combination with gabapentin, including alcohol, opioids, benzodiazepines, antidepressants, and other CNS depressants 13,14,15. Gabapentin isn’t considered a controlled substance by the federal government as of July 2022. But several states consider gabapentin a schedule V (schedule 5) controlled substance. In states where gabapentin is a controlled substance, there’s stricter laws regarding prescribing and dispensing it from pharmacies.
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