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Gabapentinoids, also known as α2δ ligands, are a class of drugs that are chemically derivatives of the inhibitory neurotransmitter gamma-Aminobutyric acid (GABA) (i.e., GABA analogues) which bind selectively to the α 2 δ protein that was first described as an auxiliary subunit of voltage-gated calcium channels (VGCCs). [1][2][3][4][5] Gabapentin is a medication that treats nerve pain by calming overactive nerves in your body. It may also prevent and control seizures in people with epilepsy. You can take this medication by mouth with a glass of water. Gabapentin (Neurontin, Gralise, Horizant) is a medicine used to treat partial seizures, nerve pain from shingles and restless leg syndrome. It works on the chemical messengers in your brain and nerves. Gabapentin is from a group of medicines called anticonvulsants. Wikipedia® on Wikimedia Foundationin rekisteröimä tavaramerkki. Sitä myydään Suomessa valmistenimellä Gabapentin, Gabrion ja Neurontin. [3] Gabapentin (kemiskt namn 1-(aminometyl)cyklohexanättiksyra [1]) är ett antiepileptikum som används vid epilepsi och smärtsam diabetesneuropati. Det är en GABA -analog; däremot agerar den inte på GABA-receptor utan inhiberar specifika kalciumkanaler. Gabapentin is commonly used to treat and prevent seizures in people with epilepsy or to treat nerve pain (postherpetic neuralgia) that can occur after a viral infection called shingles. Il gabapentin [2] è il nome del principio attivo indicato specificamente nel dolore post-erpetico e nell'epilessia parziale resistente alle terapie standard. È un farmaco analgesico e anticonvulsivante . A gabapentin epilepszia, nyugtalan láb szindróma (en) és neuropátiás fájdalom (en) elleni hatóanyag. Használják mellrák-kezelés vagy menopauza okozta bőrpír és izzadás ( hőhullám (en) ) ellen is. Gabapentina este utilizată ca medicament anticonvulsivant, în tratamentul unor tipuri de epilepsie, mai exact: [9] [10] [11] tratamentul adjuvant al convulsiilor parțiale, cu sau fără generalizare secundară, la copii și adulți Common Trade Names: Neurontin, Gralise; Adult Dosing Partial Seizures. Adjunctive therapy for partial seizures with or without secondary generalization; Initial: 300mg PO q8hr; May increase up to 600mg PO q8hr; Post herpetic neuralgia. Day 1: 300mg PO qDay; Day 2: 300mg PO q12hr; Day 3: 300mg PO q8hr; Muscle Cramps (Off-label) Gabapentin enacarbil (Horizant (ER) (U.S. Tooltip United States), Regnite (in Japan)) is an anticonvulsant and analgesic drug of the gabapentinoid class, and a prodrug to gabapentin. [1] Gabapentin is used to control seizures, to treat nerve pain that can happen after having had shingles, and to treat a condition called restless legs syndrome. In addition to these FDA-approved uses, doctors sometimes prescribe gabapentin off-label. Gabapentin, sold under the brand name Neurontin among others, is an anticonvulsant medication primarily used to treat neuropathic pain and also for partial seizures [10] [7] of epilepsy. It is a commonly used medication for the treatment of neuropathic pain caused by diabetic neuropathy, postherpetic neuralgia, and central pain. [11] Gabapentin besitzt dabei eine Halbwertszeit von 5 bis 7 Stunden im Blut, ausgeschieden wird es über den Harn. [17] Während Gabapentin beim Menschen unverändert ausgeschieden wird, erfolgt beim Hund eine Verstoffwechslung zu N-Methyl-Gabapentin, weshalb bei Hunden eine schnellere Elimination und damit kürzere Wirksamkeit zu verzeichnen ist. [18] 가바펜틴(Gabapentin)는(상품명으로 '뉴론틴' 등이 사용된다) 1973년 미국 화이자사가 개발하여, 뇌전증 및 신경성 통증에 사용되어, 약물과의 상호 작용이 적은 삶의 질을 높이는 항경련제이다. Gabapentin is approved to prevent and control partial seizures, relieve postherpetic neuralgia after shingles and moderate-to-severe restless legs syndrome. Learn what side effects to watch for, drugs to avoid while taking gabapentin, how to take gabapentin and other important questions and answers. Gabapentin is an anticonvulsive medication that received approval from the US Food and Drug Administration (FDA) in 1993 and has been available in generic form in the USA since 2004. Gabapentin was originally used as a muscle relaxant and an anti-spasmodic. Gabapentin, yang dijual di bawah jenama Neurontin, ialah ubat anti-kejang yang digunakan untuk dalam rawatan sawan separa, sakit neuropatik, kilat panas dan sindrom kaki resah. [ 4 ] [ 5 ] Ia adalah antara ubatan yang disyorkan sebagai sebahagian daripada rawatan permulaan bagi rawaran neuropati diabetik, neuralgia postherpetik dan sakit Gabapentin, được bán dưới tên thương hiệu Neurontin và các thương hiệu khác, là một loại thuốc chống co giật được sử dụng để điều trị co giật một phần, đau thần kinh, bốc hỏa và hội chứng chân không yên. Gabapentina é um fármaco da classe dos anticonvulsivantes, análogo de GABA.Foi desenvolvido para o tratamento da epilepsia e acabou também por passar a ser utilizado para o tratamento de dor ocasionadas pelos nervos periféricos.
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