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Hypothetically, gabapentin-induced GABA A receptor activation could stimulate insulin release resulting in hypoglycaemia. Alternatively, direct binding to the alpha 2 -delta 2 receptor of the voltage-gated calcium channels could also provide a pharmacological explanation. The short answer is: yes, it is possible, though not very common, for gabapentin to raise your blood sugar. Studies have shown that approximately 1.2% of patients treated with gabapentin may experience hyperglycemia (high blood sugar) compared to 0.4% with a placebo. No, gabapentin does not directly cause high blood sugar levels. Current research indicates that there is no significant link between gabapentin use and elevated glucose levels. The medication primarily affects neurotransmitter activity and does not alter insulin function directly. gabapentin, dosage, blood disorders. Further information. Gabapentin uses and safety info; Gabapentin prescribing info & package insert (for Health Professionals) Side effects of Gabapentin (detailed) Similar questions Summary: High blood sugar is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lantus, and have Depression. The patient was consulted to the pain clinic for uncontrolled pain and initiated and titrated on gabapentin from 300 mg per day to 600 to 900 mg 3 times per day. Two weeks later, the patient's glucose levels increased to levels of 150 to 165 mg/dL. OTC medicines that can raise your blood sugar include: Pseudoephedrine, a decongestant in some cold and flu medicines; Cough syrup. Ask your doctor if you should take regular or sugar-free. Gabapentin use may cause hypoglycemia in both diabetic and non-diabetic patients, requiring monitoring and informed patients about the risk. Gabapentin may cause mild hyperglycemia in patients with type 2 diabetes mellitus, but this case was not considered due to adequate pain control. Gabapentin has not been reported to raise blood sugar, however it would be best to consult a pharmacist/doc who would have prescribed the med. Take care, be well & safe! While there is evidence suggesting that gabapentin can potentially raise blood sugar levels in some individuals, particularly those with pre-existing diabetes, there are also multiple reports of gabapentin causing hypoglycemia. Her blood glucose level was 33 mg/dL. Gabapentin was started 1 week prior to the hypoglycemia episode. Her past medical history, concomitant medications, and other amounts can raise blood sugar.) Calcipotriene + betamethasone (Enstillar®) Candesartan + hydrochlorothiazide (Atacand HCT®) Captopril + hydrochlorothiazide (Capozide®) Carfilzomib (Kyprolis®) Carteolol (Cartrol® oral, Occupress® eyedrops) Carvedilol (Coreg®) Ceftaroline (Teflaro®) Ceftozolane + tazobactam (Zerbaxa) Chlorothiazide (Diuril®) Hyperglycemia is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lantus, and have Depression. Gabapentin is taken by mouth and comes in capsule, tablet, and liquid form. Conditions treated with gabapentin. Gabapentin is FDA-approved as Neurontin to treat partial seizures in adults and children with epilepsy. Partial seizures are convulsions that originate from a single location in the brain. Summary: Blood glucose abnormal is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Metformin, and have Type 2 diabetes. But certain drugs can raise blood sugar levels — including some very common ones. Sometimes, the increase in blood sugar is temporary and goes away when you stop taking the medication. But medications can also increase the risk of developing Type 2 diabetes in people who don’t have diabetes yet. Gabapentin appears to have effects on several voltage-gated calcium channels. Hypoglycemia may be due to gabapentin binding to the alpha<sub>2</sub>delta subunit of the calcium channels in the pancreas. Future research should investigate gabapentin and the potential for hypoglycemia. Postmarketing research of gabapentin has shown fluctuation of blood glucose levels. Ask your doctor to evaluate your blood glucose levels for hypoglycemia. He/she might want to adjust your dose of gabapentin, or send you to a dietician to establish a special diet to control the low blood sugar if your glucose is not dropping too severely. K askyourpharm.com Despite adequate pain control achievement following gabapentin initiation, blood glucose values continued to rise. From a search of the medical literature, 2 articles speak to the effect of gabapentin on blood glucose levels.
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