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Title: Six cases of (severe) hypoglycaemia associated with gabapentin use in both diabetic and non-diabetic patients Author: Joep H. G. Scholl, Rike Eekeren, Eugène P. Puijenbroek Gabapentin is in a class of medications called anticonvulsants. What are the brand names of gabapentin? Gabapentin is available as both a brand name product and a generic product (chemically the same, usually lower cost than the brand name product). Brand names of gabapentin include Horizant®, Gralise® and Neurontin®. If one of them may affect your blood sugar, they may prescribe a lower dose or tell you to take the medicine for a shorter time. You may need to check your blood sugar more often while you’re The short answer is: yes, it is possible, though not very common, for gabapentin to raise your blood sugar. Studies have shown that approximately 1.2% of patients treated with gabapentin may experience hyperglycemia (high blood sugar) compared to 0.4% with a placebo. The SmPC of gabapentin mentions blood glucose fluctuations in diabetic patients as a potential adverse drug reaction with unknown frequency [1]. The current observation describes the association between gabapentin and severe hypoglycaemia in diabetic and non-diabetic patients. Reports The patient was managed supportively and D5 water was started due to hypoglycemia and later on switched to D10 water given prolonged and low blood sugars findings. however effective glycemic control was only achieved after starting adjuvant tube feeds. No other home medication was found with documented side effects of hypoglycemia. Gabapentin has been associated with both hypoglycemia and hyperglycemia in different patient cases. The drug's interaction with GABA receptors and voltage-gated calcium channels may influence insulin secretion, leading to these varying effects on blood sugar levels. Drugs That May Cause Hypoglycemia (Low Blood Sugar) - Continued Hydrochlorothiazide + metoprolol (Lopressor HCT®) Insulin (Lantus®, Levemir®, NPH®, Humulin®, Novolin®, Apidra®, Novolog®, Humalog®, Tresiba®, Afrezza® - inhaled, Abasaglar®, Ryzodeg®, Xultophy®- not FDA approved, Toujeo® , Locemia®- not FDA approved, V-go®) Hypothetically, gabapentin-induced GABA A receptor activation could stimulate insulin release resulting in hypoglycaemia. Alternatively, direct binding to the alpha 2 -delta 2 receptor of the voltage-gated calcium channels could also provide a pharmacological explanation. Gabapentin is used to control seizures, to treat nerve pain that can happen after having had shingles, and to treat a condition called restless legs syndrome. In addition to these FDA-approved uses, doctors sometimes prescribe gabapentin off-label. 41f here. Anyone experience a drop in blood sugar while taking this? I’m not sure if it’s a faulty freestyle libre 3 or if the results are accurate. Showed my levels at under 60 all night. This is all new to me since I’m experiencing blood sugar regulation issues at the beginning of perimenopause. Began some medical journal research and found an obscure paper indicating that, in rare instances, gabapentin may cause lowering of blood sugar. Since then my oral blood sugar medication requirements have dropped significantly. Her blood glucose level was 33 mg/dL. Gabapentin was started 1 week prior to the hypoglycemia episode. Her past medical history, concomitant medications, and other Controlling the patient’s pain with gabapentin would decrease blood glucose values. The patient was consulted and scheduled in the pain clinic during week 38 for uncontrolled right side pain. The patient had a history of right side pain for the previous 6 years. It’s very unusual for otherwise healthy people to have blood glucose levels that are too high or too low. But certain drugs can raise blood sugar levels — including some very common ones. Sometimes, the increase in blood sugar is temporary and goes away when you stop taking the medication. Common adverse effects from gabapentin include somnolence, sedation, and dizziness. Hyperglycemia is listed as a possible adverse drug reaction in the labeling. Case reports describe hypoglycemia in patients with diabetes, peritoneal dialysis, and/or incomplete medication records. 2 Answers - Posted in: gabapentin, blood disorders - Answer: My wife is type 2 diabetic and takes gabapentin for years and it does not So, I started taking Gabapentin about 2 weeks ago for lower back pain, and within the past week, I’ve noticed that it is much more easy for me to spike my blood sugar up. Even eating a single cookie gives me symptoms of mild hyperglycemia like a headache and blurred vision. 1 Answer - Posted in: gabapentin, dosage, blood disorders - Answer: Hi.. yes..High Blood Sugar rare side effects of Neurontin.. please consult The most common gabapentin (Neurontin) side effects are dizziness and drowsiness. This may affect your ability to drive or perform other activities. Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common.
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