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However the dose is usually not more than 12 mg of olanzapine and 50 mg of fluoxetine per day. Children younger than 10 years of age—Use and dose must be determined by your doctor. For treatment resistant depression (olanzapine with fluoxetine): Adults—At first, 5 milligrams (mg) of olanzapine and 20 mg of fluoxetine once a day in the evening. Review detailed drug interaction details between Gabapentin and Olanzapine, including severity, interaction details, how to manage the interaction, and more. This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Where should I keep my medication? Keep out of the reach of children. Store at controlled room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and Applies to: gabapentin and Zyprexa (olanzapine) Using gabapentin together with OLANZapine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. Carbamazepine and gabapentin. As with valproate, the coadministration of carbamazepine with gabapentin appears safe, with no significant interactions . Hence, dose adjustments and additional blood level monitoring are not necessary. Zyprexa side effects. Zyprexa may cause serious side effects such as an increased risk of death or stroke in elderly patients with dementia, a higher risk of suicide when taken with fluoxetine, metabolic changes, tardive dyskinesia, low blood pressure, and blood cell disorders. See the warnings below for a full list of serious side effects. The phase IV clinical study analyzes what interactions people have when they take Zyprexa and Gaba. It is created by eHealthMe based on reports of 2 people who take the same drugs from the FDA, and is updated regularly. Side Effects of Zyprexa. Like any medication, Zyprexa (olanzapine) can cause side effects. Common side effects may include weight gain, increased appetite, drowsiness, dizziness, dry mouth, constipation, and changes in personality. It is important to note that not everyone will experience these side effects, and they may vary in severity. There are many medications, supplements, and foods that can interact with olanzapine because of how it’s broken down in the body. Carbamazepine (Tegretol), alcohol, and blood pressure medications are a few examples of things that can cause an interaction. Use WebMD’s Drug Interaction Checker tool to find and identify potentially harmful and unsafe combinations of prescription medications by entering two or more drugs in question. Skip to main 663 medications are known to interact with olanzapine. Includes amlodipine, gabapentin, lisinopril. There is some evidence for the following effects. Carbamazepine decreases the plasma concentrations of both risperidone and its active metabolite. It also decreases concentrations of olanzapine, clozapine, ziprasidone, haloperidol, zuclopenthixol, flupenthixol and probably chlorpromazine and fluphenazine. These are not all the possible side effects with Zyprexa. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Zyprexa Images. Zyprexa 2.5 mg; Zyprexa 5 mg; Zyprexa 7.5 mg; Zyprexa 10 mg; Zyprexa 15 mg; Zyprexa 20 mg • To prevent serious side effects, do not stop taking ZYPREXA suddenly. If you need to stop taking ZYPREXA, your doctor can tell you how to safely stop taking it. • If you take too much ZYPREXA, call your doctor or poison control centerat 1-800-222-1222right away, or get emergency treatment. • ZYPREXA can be taken with or without food. Adding gabapentin to olanzapine. Olanzapine is principally metabolized by CYP1A2 and CYP2D6. Gabapentin is eliminated unchanged by the kidney for 100%. This combination of drugs may have possible synergistic effects. There are no reports for pharmacokinetic drug interactions. However, the combination will have additional side effects. The following nonprescription products may interact with olanzapine: allergy medications (diphenhydramine, loratadine, fexofenadine, chlorpheniramine or cetirizine); omeprazole (Prilosec). Be sure to let your doctor and pharmacist know that you are taking these medications before you start taking olanzapine. Lactation risk: Olanzapine is excreted into breast milk. Brest-feeding is not recommended by manufacturer. Renal Dosing. No dosage adjustment is necessary, not removed by dialysis. Hepatic Dosing. Use with caution, in combination with fluoxetine, initial dose of olanzapine should not exceed 2.5-5 mg daily. Contraindications. Allergy to class/drug Could your schizophrenia medicines interact with other drugs you take? WebMD shows you the warning signs, and when to call your doctor. Olanzapine (Zyprexa) is a medication that works in the brain to treat schizophrenia. Olanzapine is also known as a second-generation antipsychotic (SGA) or atypical antipsychotic, and rebalances dopamine and serotonin to improve thinking, mood, and behavior. Olanzapine, sold under the brand name Zyprexa among others, is an atypical antipsychotic primarily used to treat schizophrenia and bipolar disorder. [13] It is also sometimes used off-label for treatment of chemotherapy-induced nausea and vomiting [14] and as an appetite stimulant. [15]
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