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They can help screen for possible drug interactions with duloxetine (Cymbalta) and check that all your medications are safe to take together. For example, your risk for bleeding might be higher if you take duloxetine (Cymbalta) with blood-thinning medications like aspirin or warfarin (Coumadin) . Together, you can weigh the risks and benefits of breastfeeding while taking the drug and discuss your other treatment and feeding options. Cymbalta precautions This drug comes with several Can you take gabapentin and Cymbalta together? It is generally not advisable to take gabapentin and Cymbalta together without close medical supervision due to the risk of drug interactions and overlapping side effects. I am taking 300mg of Gabapentin twice a day and my neurologist seems to feel pretty strongly that I add 30mg of Cymbalta. Does anyone else take this combo? I really hate adding new medications! Gabapentin + Cymbalta The following applies to the ingredients: Gabapentin and Duloxetine (found in Cymbalta) MONITOR: The efficacy of anticonvulsants may be diminished during coadministration with selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitor (SNRIs). Yes: Cymbalta (duloxetine) and gabapentin can both be taken together without interfering with the effect of each medication, but do keep in mind that both medications can cause you to feel drowsy. A Moderate Drug Interaction exists between Cymbalta and gabapentin. View detailed information regarding this drug interaction. For most individuals, it is safe to take gabapentin and Cymbalta (duloxetine) together. In fact, they are commonly used in combination to treat certain conditions, like neuropathy (nerve-type pain). There are some precautions, that I list below, but generally, they are of low risk. While cymbalta and gabapentin are prescribed for different conditions, they may be used together in some cases, as determined by a healthcare professional. It is important to follow the prescribed dosage and instructions provided by your healthcare provider. Can you take Duloxetine and Gabapentin together? Let us see what happens when you take Duloxetine and Gabapentin together. What is Duloxetine? Duloxetine is a Selective and Norepinephrine Reuptake Inhibitor Antidepressant (SSNRI). Duloxetine treats major depressive and general Anxiety disorders in adults and children at least seven years old. Gabapentin and Cymbalta (duloxetine) are used to treat different types of neuralgia (nerve pain). Gabapentin is used postherpetic neuralgia from herpes zoster (nerve damage from shingles) and to treat seizure disorders. The following applies to the ingredients: Gabapentin and Duloxetine (found in Cymbalta) MONITOR: The efficacy of anticonvulsants may be diminished during coadministration with selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitor (SNRIs). Understanding Synergies and Repercussions In the realm of pharmaceuticals, the amalgamation of diverse remedies can yield both fortuitous synergies and unforeseen consequences. Delving into the labyrinth of pharmaceutical interactions unveils a dynamic interplay between substances, where their combined influence can transcend individual efficacy. Navigating the Terrain of Compatibility I’ve been on Gabapentin for over a year now. It works well for managing severe pain and I have better mobility. I have Syringomyelia as well as Fibromyalgia. However, I still have terrible stiffness and fatigue. My PCP wants me to try adding Cymbalta and then eventually it will replace Gabapentin. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For oral dosage form (delayed-release capsules): For treatment of anxiety: Use WebMD’s Drug Interaction Checker tool to find and identify potentially harmful and unsafe combinations of prescription medications by entering two or more drugs in question. @boisvert Hi, I have been using 90mg daily of Cymbalta for several years without side effects for pain. Gabapentin was never helpful for me. My husband uses it and has had to increase gabapentin dosage as his tolerance builds, where once I found my correct dose of Cymbalta, it's been steady. The following applies to the ingredients: Gabapentin and Duloxetine (found in Cymbalta) Treatment with DULoxetine may occasionally cause blood sodium levels to get too low, a condition known as hyponatremia, and using it with some anticonvulsants can increase that risk. I'm taking 160 mgs duloxetine and 2400 mgs of gabapentin daily. So far I haven't had problems. The duloxetine is for severe depression caused by chronic pain and the gabapentin is for restless leg syndrome and nerve pain. Most people experience side effects with Cymbalta and one in six people stop taking the drug because of them. Severe skin reactions and urinary retention have also been reported with Cymbalta. An increased risk of suicidal thoughts, especially in young adults under the age of 24 (similar to other antidepressants).
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