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Among these, 4,642 (0.26%) were exposed to gabapentin during T1, 3,745 (0.21%) were exposed to gabapentin early in pregnancy only (during the first 140 days), 556 (0.03%) were exposed late in pregnancy but not early, and 1,275 (0.07%) were exposed in both early and late pregnancy . Your healthcare providers can talk with you about the benefits of treating your condition and the risks of untreated illness during pregnancy. I take gabapentin. Can it make it harder for me to get pregnant? It is not known if gabapentin can make it harder to get pregnant. Sexual dysfunction (including loss of desire to have Your healthcare providers can talk with you about the benefits of treating your condition and the risks of untreated illness during pregnancy. I take gabapentin. Can it make it harder for me to get pregnant? It is not known if gabapentin can make it harder to get pregnant. Sexual dysfunction (including loss of desire to have Some seizures can stress the body so much that it may lead to a miscarriage. Taking gabapentin is overall safer than having seizures while pregnant. Should You Take Gabapentin While Pregnant? Gabapentin is a potent anticonvulsant medication, and most studies show that it should not harm a developing fetus. Gabapentin (Neurontin) use in pregnancy is complex. Talk to your doctor to decide if it's right for you. Read to learn more. It is not known if gabapentin can make it harder to get pregnant. Sexual dysfunction (including loss of desire to have sex and loss of ability to have an orgasm) has been reported among people who take gabapentin. Does taking gabapentin increase the chance of miscarriage? Review clinical studies: Ask your health care provider if they can provide you with information on clinical trials or research that has been conducted on pregnant women who have taken Gabapentin during pregnancy; Consider risk factors: You should also discuss any individual risk factors that may increase the likelihood of adverse effects due to While gabapentin (Neurontin) is now used in a wide variety of clinical settings — for epilepsy, pain management, restless leg syndrome, anxiety, and sleep disturbance – there is relatively little information regarding its reproductive safety. Research suggests that women who take gabapentin during pregnancy may have a higher likelihood of giving birth to babies with malformations, such as cleft lip, cleft palate, and heart defects. There was an increased risk of preterm birth among women exposed to gabapentin either late (RR=1.28 [CI 1.08-1.52], p < 0.01) or both early and late in pregnancy (RR=1.22 [1.09-1.36], p < 0.001). While gabapentin can pass into breast milk in small amounts, it is often considered relatively safe for use during breastfeeding if the potential benefits to the mother outweigh the risks to the infant. If your doctor or health visitor says your baby is healthy, you can take gabapentin while breastfeeding. It's important to keep taking gabapentin to keep you well. Gabapentin passes into breast milk in small amounts. Are there any risks of taking gabapentin during pregnancy? Gabapentin use in pregnancy is not very well-studied. While the available information does not strongly suggest that it causes problems for the baby, further research is required to prove that gabapentin is safe. It is not known if gabapentin can make it harder to get pregnant. Sexual dysfunction (including loss of desire to have sex and loss of ability to have an orgasm) has been reported among women who take gabapentin. More research is required to define the pregnancy safety profile of gabapentin. Pregnant women and women of childbearing potential should be made aware of the lack of data for most pregnancy outcomes. Gabapentin should only be used during pregnancy where benefits of treatment are considered to outweigh any potential risks. Advice and warnings for the use of Gabapentin during pregnancy. FDA Pregnancy Category C - Risk cannot be ruled out If you have an unplanned pregnancy while taking a medicine, you should tell your doctor as soon as possible. If a new medicine is suggested for you during pregnancy, please make sure that the person prescribing it knows that you are pregnant. If you have any concerns about a medicine, you can check with your doctor, midwife or pharmacist. Gabapentin may be used during pregnancy only when the benefits outweigh the potential risks. In animal studies, gabapentin has been shown to increase the risk for fetal malformation, particularly delayed bone formation. The researchers reported 2 major malformations in infants exposed to gabapentin in the first trimester of pregnancy. 3 In another group of 7 women with hyperemesis gravidarum, 2 congenital defects were reported. 4 A cohort study in Denmark reported on 59 fetuses exposed to gabapentin during pregnancy, and documented 1 major malformation and 6
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