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my mother was on Neurontin & its generic version, gabapentin, for nerve pain. At the same time she had been prescribed Lantus if her blood sugar went over a certain number. She did not have diabetes but was specifically prescribed Lantus because of her medications (she was on blood pressure meds but Lantus was prescribed when Neurontin was added. Gabapentin is an anticonvulsant (antiseizure) medication approved by the FDA to treat several conditions. Doctors sometimes prescribe gabapentin "off-label" to treat other conditions as well. A 2022 report stated that gabapentin was among the 10 most commonly prescribed medications in the U.S. What is gabapentin and what is it used for? Prescription medicines that can raise your glucose include: Steroids (also called corticosteroids). They treat diseases caused by inflammation, like rheumatoid arthritis, lupus, and allergies. Blood glucose abnormal is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Metformin, and have Type 2 diabetes. Drugs That May Cause Hypoglycemia (Low Blood Sugar) - Continued Hydrochlorothiazide + metoprolol (Lopressor HCT®) Insulin (Lantus®, Levemir®, NPH®, Humulin®, Novolin®, Apidra®, Novolog®, Humalog®, Tresiba®, Afrezza® - inhaled, Abasaglar®, Ryzodeg®, Xultophy®- not FDA approved, Toujeo® , Locemia®- not FDA approved, V-go®) I've been on gabapentin for the same thing. Didn't notice a big difference with my blood sugar, but do notice I run higher while managing pain. Hope you find some relief from both pain and pesky highs. yes..High Blood Sugar rare side effects of Neurontin.. please consult with your health care provider as soon as possible.. good luck. Summary: High blood sugar is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lantus, and have Depression. More rarely, gabapentin can cause fluid buildup (edema), weight gain, and vision problems. It can also cause diarrhea. More serious (but rare) side effects include suicidal thoughts or behavior, and mood changes in children. Gabapentin can be used to treat pain and sleep interference associated with diabetic peripheral neuropathy and it generally appears to be safe for people with diabetes, but the risk of hyperglycemia should be considered, and blood sugar levels should be carefully monitored. Conclusion: A 63-year-old Caucasian gentleman with type 2 diabetes mellitus developed a possible case of gabapentin-induced mild hyperglycemia after receiving gabapentin for several months with a dose titration. Gabapentin could be considered as a cause for otherwise unexplained hyperglycemia in a patient. Began some medical journal research and found an obscure paper indicating that, in rare instances, gabapentin may cause lowering of blood sugar. Since then my oral blood sugar medication requirements have dropped significantly. Hyperglycemia, or high blood sugar, can be a side effect of some common medications. Sometimes, high levels of blood sugar are temporary and settle when you stop taking the medication. But certain medications can increase the risk of developing Type 2 diabetes. Gabapentin has been associated with both hypoglycemia and hyperglycemia in different patient cases. The drug's interaction with GABA receptors and voltage-gated calcium channels may influence insulin secretion, leading to these varying effects on blood sugar levels. Some studies suggest gabapentin may cause hypoglycemia in both diabetic and non-diabetic patients, while other studies suggest it may cause mild hyperglycemia in patients with type 2 diabetes mellitus. If gabapentin causes any fluctuations in glucose levels, modification of drug therapy is warranted to correct the abnormalities and an association with gabapentin may go unnoticed. In addition, the number of patients with diabetes receiving gabapentin may not be known at a specific point in time. The study uses data from the FDA. It is based on gabapentin (the active ingredients of Gabapentin) and Gabapentin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Gabapentin has not been reported to raise blood sugar, however it would be best to consult a pharmacist/doc who would have prescribed the med. Take care, be well & safe! gabapentin, blood disorders. Still looking for answers? Try searching for what you seek or ask your own question. Although blood glucose fluctuations are a possible adverse drug reaction (ADR) of gabapentin 1, hypoglycaemia in relation to this drug was found in just one publication 3. We received six cases of (severe) hypoglycaemia in both diabetic and non-diabetic patients exposed to gabapentin, which occurred between July 2002 and July 2012. While there is evidence suggesting that gabapentin can potentially raise blood sugar levels in some individuals, particularly those with pre-existing diabetes, there are also multiple reports of gabapentin causing hypoglycemia.
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