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Higher doses and longer treatment periods increase your risk of weight gain [11]. People who take Gabapentin might gain about 5 pounds after just 6 weeks of use [12]. Weight gain affected 3% of patients over 12 years old with epilepsy, compared to 2% who took a placebo [12]. More rarely, gabapentin can cause fluid buildup (edema), weight gain, and vision problems. It can also cause diarrhea. More serious (but rare) side effects include suicidal thoughts or behavior, and mood changes in children. It reported a 3.86% weight gain with pregabalin. The conclusion: “In conclusion, the present study showed that drug-induced weight gain is a common side effect of several medications frequently used to treat chronic diseases. Healthcare providers should educate their patients about the medicines that may cause weight gain.” Gabapentin can cause fluid buildup in the legs (edema), which can lead to temporary weight gain. You can also gain weight without fluid buildup, though it’s not common. You may be able to avoid weight gain from gabapentin by adjusting your diet and exercising regularly. How do you avoid gaining weight while taking gabapentin? What is the right gabapentin dosage for me? Can you drink alcohol while taking gabapentin? Is gabapentin addictive? Is it safe to take gabapentin for sleep? How does gabapentin work? Researchers are not entirely sure how gabapentin works. Yes, gabapentin can cause weight gain. One review article looking at weight gain from medications found an average weight gain of almost 5 pounds after just 1.5 months on gabapentin. Gabapentin has been found to cause weight loss in some people, but weight gain in others. To understand why Gabapentin causes weight loss or weight gain, we need to understand the mechanism by which it works. Weight gain was more likely, particularly in pediatric patients. A total of 1.8 to 2.9 percent of adolescents and adults in some clinical trials with Neurontin experienced weight gain. In one study with children aged 3 to 12 years, 3.4 percent gained weight while taking Neurontin, compared with 0.8 percent taking a placebo. It can also cause an increase in appetite and weight gain. One study showed than in patients taking high doses of gabapentin for at least 12 months, most patients gained weight and only a few maintained or lost weight. A review of research examining antipsychotic medicine explains why: Most of those drugs cause weight gain. Over the course of treatment, around 7 in 10 patients will gain weight — rapidly in the initial period after starting these meds, but it continues over the long term. The risk appears to be highest with: Olanzapine (Zyprexa) Clozapine Gabapentin is a nerve medication that may cause weight gain in some patients. The best way to manage gabapentin weight gain is with a good diet and healthy habits. A registered dietitian is an excellent partner to help navigate weight changes as a result of medication. Weight gain is not considered a common side effect of gabapentin. In clinical trials, only about 2% of people reported weight gain with its use. In people who do gain weight while on gabapentin, a research study showed a weight gain of about 5.5 pounds after 1.5 months of use. weakness or loss of strength; weight gain; Nemire RE, Haley K (1995) "Weight gain and gabapentin therapy." Ann Pharmacother, 29, p. 1048. Does it cause weight 14 Answers (question resolved) - Posted in: gabapentin, weight, appetite - Answer: Hi my experience with this med is a weight gain even you eat a Gabapentin is a drug that isn’t associated with clinically significant weight gain. It is estimated that approximately 3% of all users will experience some form of weight gain. Most people won’t notice any significant fluctuations in body weight throughout their treatment. For this reason, Gabapentin is often referred to as a “weight neutral” drug. 1. How much weight can I expect to gain on gabapentin? Weight gain is highly individual and varies widely. While some studies report about 5 pounds gained in 6 weeks, individual results can differ significantly, and not everyone gains weight. 2. Does gabapentin always cause weight gain? No, gabapentin doesn’t always cause weight gain. Many Similar weight change was noted with exenatide 10, 15, and 20 μg. The weight loss with exenatide weekly dosing was 0.9 kg, and with daily dosing it was 1.3 kg (P value for difference = .7). Weight loss with GLP-1 agonists used < 3 months was 0.3 kg, 3–6 months was 1.3 kg, and > 6 months was 0.9 kg. Gabapentin and weight gain: not a fun mix. Unfortunately, weight gain is a common side effect of many medications. From a fluctuation in hormones to water retention to changes in appetite, drugs like gabapentin can cause some unwanted weight gain. Gabapentin may cause weight gain, but it is an uncommon side effect. Studies have shown that a small number of people taking gabapentin, a drug used to treat epilepsy and postherpetic neuralgia, experienced weight gain. People who do gain weight may gain about 5 pounds after 6 weeks of use.
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