Gabapentin and Weight Gain Posted by pah17 @pah17 , Oct 12, 2024 Within the past year I have gradually gained at least 5 lbs. and my stomach protrudes. Divalproex was associated with increased risk of weight gain (of any magnitude), but not of clinically significant (≥5%) weight gain (relative risk, 2.8; 95% CI, 1.30, 6.02; and relative risk, 1.39; 95% CI, 0.38, 5.14, respectively; data insufficient to determine absolute weight difference). Does gabapentin cause weight gain? Some research indicates that 2% to 3% of people taking gabapentin gain weight. Often, this is temporary and due to peripheral edema (fluid buildup in the ankles and feet). See what Gabapentin users say about weight gain. Out of 2570 reviews, 97 (3.8%) mention weight gain. Read firsthand experiences. Although it’s uncommon, edema from gabapentin may lead to weight gain. If you experience edema or weight gain while taking gabapentin, let your prescriber know, but don’t stop taking the medication until you speak with them. Gabapentin (Neurontin, Gralise, Horizant) is a medicine used to help manage certain epileptic seizures. It also is used to relieve pain for some conditions, such as shingles. Dizziness and drowsiness are common side effects of gabapentin. Some other possible side effects include weight gain and trouble with movement. It's just an uncommon side effect that isn't always experienced. A PubMed study investigating the effect of Gabapentin on 44 patients found that 10 patients gained more than 10% of their original weight, 15 patients gained 5% more, 16 patients had no change, and 3 patients lost 10% of their original weight. Gabapentin is thought to cause weight gain by increasing patients’ appetites and causing fatigue that reduces their physical activity. It can also cause water retention, with swelling (edema) of the hands, arms, feet, and legs, which may contribute to weight gain. Related: Does Trazodone cause weight gain? One study found that in patients One study found gabapentin was associated with a weight gain of 2.2 kg after 1.5 months of use; In another small study, almost half of the participants gained at least 5% of their baseline weight; Why does gabapentin cause weight gain? There are several possible explanations for gabapentin weight gain: Reviews and ratings for Gabapentin. 2569 reviews submitted with a 7.2 average score. Does gabapentin cause weight gain? How long does it take gabapentin to work Weight gain is not considered a common side effect of gabapentin. In clinical trials, only about 2% of people reported weight gain with its use. In people who do gain weight while on gabapentin, a research study showed a weight gain of about 5.5 pounds after 1.5 months of use. A comprehensive systematic review and meta-analysis of 257 randomized trials, including gabapentin, indicated that gabapentin is associated with an average weight gain of 2.2 kg. This finding places gabapentin among several other drugs known to cause weight gain, such as amitriptyline and olanzapine . For healthcare professionals. Applies to gabapentin: compounding powder, oral capsule, oral solution, oral tablet, oral tablet extended release. General adverse events. The most common adverse reactions associated with the use of this drug were dizziness, somnolence, and peripheral edema. Additionally, gabapentin can cause multiorgan hypersensitivity or DRESS syndrome, a serious condition that requires immediate medical attention if symptoms such as rash, fever, swollen lymph nodes, or liver problems occur.Consulting with a healthcare professional and being aware of the potential risks and benefits of gabapentin are important Yes, gabapentin can cause weight gain. One review article looking at weight gain from medications found an average weight gain of almost 5 pounds after just 1.5 months on gabapentin. Gabapentin may cause weight gain, but it is an uncommon side effect. Studies have shown that a small number of people taking gabapentin, a drug used to treat epilepsy and postherpetic neuralgia, experienced weight gain. People who do gain weight may gain about 5 pounds after 6 weeks of use. Unfortunately, gabapentin can lead some patients to gain weight. However, the occurrence is considered rare and is unlikely to affect most people. The good news is that you can elude weight gain by leading a healthy lifestyle that combines a balanced diet with regular physical activity. Patients who have been prescribed gabapentin are often concerned about weight gain as a side effect. However, they should note, weight gain is a very rare side effect, observed in less than 5% of patients. In cases where weight gain does occur, it is typically a result of an increased appetite or reduced exercise caused by the drug. The authors reviewed changes in body weight in 44 patients treated with Gabapentin (GPN) for a period of 12 or more months. All patients had a seizure disorder and the dose of GPN was increased aiming at complete seizure control or until side effects limited further increase. Twenty-eight patients w
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