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Evidence suggests that the pain after laparoscopic cholecystectomy stems from somatic due to incisional pain and surgical trauma to the abdominal walls at the trocar port insertion sites. 3, 4 Another component of postoperative pain after laparoscopic cholecystectomy is visceral pain which is classified as intra-abdominal pain caused by the manipulation and distention of the intra-abdominal Gabapentin is an anticonvulsant drug that can be effective in postoperative pain control. Objectives: This study examined the effect of preoperative administration of gabapentin on reducing pain after LGBP in patients with morbid obesity. Similarly, aside from 24 h after surgery, gabapentin significantly reduced pain with movement (25–27,31,34,35,37,38) by 18% to 28% (VAS 8.2 mm to 10.2 mm) after surgery . The pooled effects on VAS pain scores displayed significant heterogeneity, which was not explained by subgroup analyses based on surgical procedure, gabapentin dose or study Pain after surgery is due to both surgical stimulation and neurogenic factors such as visceral tissue edema. Current pain treatment methods include several analgesic drugs with different mechanisms of treatment . Gabapentin is primarily used as an anticonvulsant drug, but recent studies have demonstrated that it also has antihyperalgesic Although laparoscopic cholecystectomy causes less pain than open cholecystectomy, it is still not completely painless. Several methods have been used to relieve the pain of laparoscopic surgery. The aim of this research was to compare the effect of gabapentin and hydrocortisone on pain control after laparoscopic cholecystectomy. Materials and They found that gabapentin resulted in a 35% reduction in total analgesic consumption in the first 24 hours following surgery. Gabapentin also resulted in 27% to 39% reduction in visual analog scale (VAS) pain scores in the first 24 hours postoperatively. Agarwal et al. found that pregabalin significantly decreased pain in patients during movement and at rest after laparoscopic cholecystectomy surgery. These results have been confirmed by Carmichael et al. [ 14 ] and Ittichaikulthol et al. [ 15 ]. 1.2 A single 300 mg dose of gabapentin should be given be should be given preoperatively colorectal surgery and for patients having laparoscopic surgery who are reducing pain intensity after surgery. The present study is aimed at examining the sedative and analgesic effects of gabapentin and dexmedetomidine in patients undergoing laparoscopic cholecystectomy. Methods: This was a double-blinded clinical trial involving 40 patients who were candidates for laparoscopic cholecystectomy. The patients were randomly allotted in two groups of dexmedetomidine Pain after laparoscopic gastric bypass surgery (LGBP) is a major problem. Gabapentin is an anticonvulsant drug that can be effective in postoperative pain control. This study examined the effect of preoperative administration of gabapentin on Post-operative gabapentin (600 mg) may be equally effective as a preoperative dose in decreasing PACU narcotic use. Concomitant administration of gabapentin as part of a multi-modal pain management strategy including narcotics, non-steroidal anti-inflammatory drugs (NSAIDS), and muscle relaxants does not improve pain scores. Preemptive premedication with 600 mg of gabapentin or 150 mg of pregabalin improves several parameters of postoperative rehabilitation after laparoscopic cholecystectomy. It reduces significantly the intensity of postoperative shoulder pain, decreases the incidence of PONV, improves the quality of sleep during the first night, and shortens the I've had good results from using gabapentin long term for chronic pain. It covers nerve pain that my morphine doesn't manage at all. My doctor used gabapentin after his hip replacement. It's the only thing he used, no narcotics at all, and he said it did the job. I know some people can have serious side effects from it but I never have. Their findings, recently published in the journal Anesthesiology, indicate that the analgesic benefits of pregabalin and gabapentin after surgery are negligible, regardless of the dose or type of operation. Gabapentinoids were also ineffective in preventing chronic pain from developing after surgery, one of the primary justifications for using Background: Pain after laparoscopic gastric bypass surgery (LGBP) is a major problem. Gabapentin is an anticonvulsant drug that can be effective in postoperative pain control. Objectives: This study examined the effect of preoperative administration of gabapentin on reducing pain after LGBP in patients with morbid obesity. Gabapentin is a novel drug used for the treatment of postoperative pain with antihyperalgesic properties and a unique mechanism of action, which differentiates it from other commonly used drugs. Various studies have shown that perioperative use of gabapentin reduces postoperative pain. Although there is strong evidence to suggest that gabapentin is effective in reducing pain scores after laparoscopic surgery, some concerns regarding the use of gabapentin in the perioperative setting are the effects on sedation and respiratory depression. We defined new postoperative gabapentin as fills for 7 days before surgery until 7 days after discharge. We excluded patients whose discharge disposition was hospice or death. The primary outcome was prolonged use of gabapentin, defined as a fill>90 days after discharge. ABSTRACT: Gynecologic surgery is very common: hysterectomy alone is one of the most frequently performed operating room procedures each year. It is well known that surgical stress induces a catabolic state that leads to increased cardiac demand, relative tissue hypoxia, increased insulin resistance, impaired coagulation profiles, and altered pulmonary and gastrointestinal function. In our study 600 mg of gabapentin decreased postoperative pain and total analgesic requirement after laparoscopic cholecystectomy. Gabapentin was designed as a hydrophobic analogue of inhibitory neurotransmitter, gamma amino butyric acid (GABA) that was able to cross blood brain barrier.
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