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Increased Appetite: Interestingly, gabapentin has been shown to increase appetite in some cats. These side effects are generally mild and temporary. If you notice these in your cat, or any other concerning changes after administering gabapentin, please contact your veterinarian . When used as prescribed and given at the recommended dose, gabapentin is safe for cats. “Gabapentin is not only safe, but remarkably effective,” Fleck says. Gabapentin and Appetite. Interestingly, gabapentin may actually increase appetite in some animals, specifically cats. Research has shown that cats receiving gabapentin may eat more than those who do not. Frequently Asked Questions (FAQs) Here are some commonly asked questions to help clarify the use of gabapentin in animals: 1. In cats, gabapentin is most often used as a pain medication for chronic pain, such as from arthritis. Gabapentin is also recognized as beneficial in reducing the fear responses that a kitty may have to the stress of handling and being examined at the vet. While gabapentin does not cause loss of appetite in cats and may even increase it, it’s vital to understand its potential side effects and administer it correctly. Consult with your veterinarian for the appropriate dosage and closely monitor your cat’s response to the medication. Interestingly, studies show that gabapentin and mirtazapine have similar effects on food intake in cats, indicating a synergy in their action to stimulate appetite. If your cat’s appetite remains poor even with gabapentin, your vet may recommend combination therapy to encourage them to eat more. Gabapentin was compared with mirtazapine in this study because of the latter’s demonstrated appetite-stimulating effect in cats: the same dose of 1.88 mg/cat PO used in the present work showed positive effects on appetite, weight gain and reduction of vomiting in cats with CKD. 31 In the cited study, appetite was documented by the owners via The short answer is that, contrary to some initial concerns, gabapentin generally increases appetite in cats. However, like many medications, its effects can vary, and understanding the full scope of its interaction with feline feeding habits is crucial. Conclusions and relevanceCats receiving gabapentin ate more than cats in the placebo group. Thirty percent of cats in the gabapentin group covered their resting energy requirements, while none of the cats in the placebo group did. Gabapentin and mirtazapine produced similar effects on food intake. Yes, gabapentin can stimulate appetite in cats, although it’s not its primary use. While more commonly prescribed for pain management, anxiety, and seizure control, research and anecdotal evidence indicate that gabapentin can have an appetite-stimulating effect in felines. For those that have given their cats Gabapentin, did you find any pattern as how far before or after their typical mealtime to time the dose to maximize the chance it will help them eat more? My cat is also on Mirataz mirtazapine ointment the past two days and it hasn't gotten him eating. Conclusions and relevance: Cats receiving gabapentin ate more than cats in the placebo group. Thirty percent of cats in the gabapentin group covered their resting energy requirements, while none of the cats in the placebo group did. Gabapentin and mirtazapine produced similar effects on food intake. Gabapentin does have a sedative effect in cats, but if your cat seems overly sleepy, it’s best to reach out to your vet. Dr. McCullough also says to call your vet if the effects of gabapentin last longer than 24 hours or if your cat experiences vomiting, diarrhea , lethargy or a decreased appetite. This double-blind, placebo-controlled study investigated the effect of gabapentin on appetite in healthy hospitalized cats following ovariectomy. Sixty cats received gabapentin (5 mg/kg PO), mirtazapine (1.88 mg/cat PO), or placebo. Food was offered 2-, 4-, 6-, and 8-hours postoperation, and intake was measured. Gabapentin is safe for cats and is commonly prescribed by veterinarians to treat pain, anxiety, and feline hyperesthesia syndrome. It has a low risk of side effects when taken at the correct dosage. Mild sedation and lethargy are the most common side effects but these tend to get better with continued dosing. If your cat is taking gabapentin in capsule or tablet form, mix the prepared powder with a small amount of your cat’s favorite food or a bit of water so they can swallow it easily. If using the liquid form, use the syringe to carefully administer the medication directly into your cat’s mouth, slowly squirting it near the back of the tongue. A study involving 47 hyperthyroid cats revealed that cats receiving a gabapentin dose of 20 mg/kg were notably more relaxed during transport and compliant during veterinary procedures. This outcome underscores gabapentin’s effectiveness as an anxiolytic, showcasing its ability to reduce stress and improve compliance in clinical settings In 2020, the gabapentin appetite-stimulating effect was evaluated in comparison to mirtazapine in healthy cats during the postoperative period, recording an increase in food intake in the gabapentin group compared to the placebo group. Surprisingly, gabapentin works fast in cats, with its effects typically noticeable within 1 hour to 2 hours after administration and lasting for approximately 24 hours. When administered, gabapentin blocks certain nerve signals in the brain, helping to calm nerve activity and diminish pain sensations.
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