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Side effects: The side effect profiles of pregabalin (Lyrica) and gabapentin (Neurontin) are similar – likely due to their identical primary mechanisms of action (involving inhibition of α2δ subunit-containing voltage-dependent calcium channels). The three most common side effects that occur with pregabalin and gabapentin include: dizziness Common side effects of pregabalin may include: dizziness, drowsiness; swelling in your hands and feet; trouble concentrating; increased appetite; weight gain; dry mouth; or. blurred vision. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Most side effects of Lyrica and gabapentin are mild and go away after using either medication for a few weeks. If the side effects bother or concern you or don’t go away, talk with your Both gabapentin and Lyrica come with side effects. The severity and likelihood depend on the person, their dosage, and any underlying health conditions. Lyrica has a higher risk of dependency, and stopping it abruptly can cause withdrawal symptoms, including nausea, anxiety, and insomnia. Both medications have common side effects, such as drowsiness, dizziness, and edema. But pregabalin is more likely to cause weight gain. More serious side effects, such as suicidal thoughts and behaviors, heart problems, or misuse, are more rare. Though the side effect profiles of both drugs are similar, some studies have found that Lyrica may have somewhat fewer of them. Dizziness and sleepiness are the most common side effects associated with both drugs, but more serious concerns such as suicidal ideation have also been reported. 1. The Bottom Line: Which is Best for Me? Lyrica (pregabalin) is a prescription drug that treats nerve pain, fibromyalgia, and other conditions. Learn about generic forms, side effects, dosage, and more. Because these drugs have few side effects and are usually well tolerated, they are often the first medications to try for neuropathic pain. Most doctors will prescribe gabapentin first; if that doesn't work, they will try pregabalin. You may experience side effects, such as drowsiness, dizziness, confusion, or swelling in the feet and legs. Gabapentin is more likely to cause different side effects from pregabalin, including: Fever; Increased risk of infection; Difficulty speaking; Jerky movements; Unusual eye movements Both gabapentin and Lyrica can cause similar side effects, though some people find one medication easier to tolerate than the other. [9] . The most common side effects include feeling dizzy, sleepy, or unsteady on your feet. With either medication, you might also notice weight gain or mild swelling in your hands and feet. Studies also show that Lyrica may be better tolerated than gabapentin. Most side effects of the drugs are 'dose-dependent', meaning they occur more often with increasing dosages. Due to the lower doses used for Lyrica, side effects tend to occur with less frequency. Controlled-Substance Status In addition, Lyrica was initially thought to have less side effects than gabapentin since the drugs are so similar to one another but Lyrica is dosed in far less amounts. However, this doesn't appear to be the case and the side effects experienced from the drugs will vary by the individual. Gabapentin is an anticonvulsant with pain-relieving effects that may be used to treat certain seizure disorders or relieve nerve pain. Common side effects include dizziness or drowsiness and it may View more. Prescription only. Pregabalin is used in the treatment of nerve pain and also to prevent seizures. Rarely, more severe side effects of gabapentin and pregabalin may include: Suicidal thoughts or behaviors Respiratory depression (slow, shallow breathing), especially if taken with other drugs or substances that are central nervous system (CNS) depressants, such as alcohol Side effects of Lyrica that are different from gabapentin include: Dry mouth; Constipation; Swelling ; Breast enlargement; Weight gain; Both gabapentin and Lyrica may interact with alcohol and drugs that cause sedation including narcotic pain medications. Gabapentin also may interact with nonsteroidal anti-inflammatory drugs . Serious side effects of Lyrica. Along with its needed effects, pregabalin (the active ingredient contained in Lyrica) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking Like most drugs, Lyrica and gabapentin can cause mild or serious side effects. The tables below include some side effects you may experience from taking either medication. For more Yes, Lyrica (pregabalin) can cause extreme drowsiness (somnolence) and may affect your ability to drive, operate machinery, or do other dangerous activities. This may lead to an injury or fall. In studies, up to 20% of children and 35% of adults experienced drowsiness as a side effect. Pregabalin (Lyrica) and gabapentin (Neurontin) are two anticonvulsant medications that treat seizures and nerve pain, as well as other off-label uses. Lyrica and gabapentin work in similar ways, but Lyrica is absorbed faster. They have similar side effects, including dizziness, drowsiness, and fluid buildup. Lyrica has an average rating of 6.4 out of 10 from a total of 925 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 26% reported a negative effect. View all 2568 reviews
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