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Dry mouth (xerostomia) can be caused by many factors, including medications. Common medications that cause dry mouth are diphenhydramine (Benadryl), Adderall (amphetamine salts), and oxybutynin. Many antidepressants, opioids, and benzodiazepines, among other medications, can also cause dry mouth. Medication-induced salivary gland dysfunction (MISGD), xerostomia (sensation of oral dryness), and subjective sialorrhea cause significant morbidity and impair quality of life. However, no evidence-based lists of the medications that cause these disorders exist. Results: Xerostomia, or dry mouth syndrome, can be caused by medication, systemic diseases such as Sjögren's Syndrome, glandular pathologies, and radiotherapy of the head and neck. Treatment of dry mouth is aimed at both minimizing its symptoms and preventing oral complications with the employment of sialogogues and topical acting substances. 2. Medications that Can Lead to a Xerostomia / Dry Mouth Side-Effect: Drugs that can cause gastroesophageal reflux (listed below): Drugs that can decrease lower esophageal sphincter pressure (listed below): Other items that can decrease lower esophageal sphincter pressure (below): Bronchodilators Atropine (Atropar) Alcohol Antiangina meds Background: Medication-induced salivary gland dysfunction (MISGD), xerostomia (sensation of oral dryness), and subjective sialorrhea cause significant morbidity and impair quality of life. However, no evidence-based lists of the medications that cause these disorders exist. Medications that affect the smooth and striated muscles of the esophagus that are involved in swallowing may cause dysphagia. Local anesthetics such as Novocain which is often used for dental work may temporarily cause a loss of sensation that may affect swallowing before it wears off. Dry Mouth: Antiepileptics like gabapentin are known to cause dry mouth, so it’s important to sip water frequently throughout the day to prevent discomfort. Weight Gain: Gabapentin doesn’t make you gain weight, but it can make you feel hungrier, causing you to gain weight. Eating a balanced diet and healthy foods that help you feel full can Xerostomia, the most common adverse drug reaction affecting the oral cavity, is associated with over 500 drugs [1, 3, 5, 6]. In a systematic review in USA, xerostomia was found as a secondary effect in 80–100% of prescribed drugs [7]. Dry mouth is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Acetaminophen, and have Stress and anxiety. Burning mouth syndrome (BMS) is a chronic oral pain syndrome that primarily affects peri- and postmenopausal women. It is characterized by oral mucosal burning and may be associated with dysgeusia, paresthesia, dysesthesia, and xerostomia. The etiology of the disease process is unknown, but is thoug Gabapentin is sold under the brand name Neurontin and is available as a generic product as well. (Generic medications are chemically the same as brand-name drugs but may cost less.) Gabapentin is also available as an extended-release tablet that works for a longer length of time; this is the only formulation that is approved for restless legs Gabapentin can help control seizures as well as nerve pain from shingles. It may sometimes cause side effects, especially if you misuse it. Learn more. The most common gabapentin (Neurontin) side effects are dizziness and drowsiness. This may affect your ability to drive or perform other activities. Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common. Check with your doctor immediately if any of the following side effects occur while taking gabapentin: More common in children. Some side effects of gabapentin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. ADRs of topical gabapentin occurred in three patients (15.8%). All three patients (15.8%) discontinued the topical gabapentin solution after the second visit due to dry mouth, sedation and the solution being uncomfortable to keep in the mouth (lip sensitivity), respectively . No patients reported any tingling sensation or “bad taste” with We study how severe was Dry mouth, when it was recovered, drug effectiveness, race, and more among people who take Gabapentin (gabapentin). This phase IV clinical study is created by eHealthMe based on reports submitted to eHealthMe, and is updated regularly. All patients diagnosed with xerostomia in the 1-year study period were identified using ICD-9 diagnosis codes for dry mouth or disturbance of salivary gland secretion (527.7, 527.8, R68.2) and Systemized Nomenclature of Medicine Clinical Terms (SNOMED CT) codes covering dry mouth, xerostomia, aptyalism, absent salivary secretion, and Xerostomia or dry mouth sensation is considered a complex condition that a ects several . Anticonvulsants Gabapentin. Antidepressants—tricyclic Amitriptyline, imipramine. I had researched dry mouth (Drug-induced Xerostomia) for at least 5 years. The document was to be completed before August but my wife passed away on August 4th. My dentist did not want to know that medications will cause cavities. Dry mouth is associated with more than 500 medications. 56 The overall prevalence of xerostomia is 10% to 33%, with an incidence of 27% to 32% in the medicated population and 14% to 16% in the
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