Electroconvulsive therapy (ECT) is an effective therapeutic option for treatment-resistant depression (TRD). [Paganin D et al., 2004] In this article, we summarise the recently published RANZCP guidelines which provide the most up to date guidance on ECT. [Weiss A et al., 2019] Aim: The goal was to determine if use of gabapentin could assist with management of myalgia and anxiety in a patient treated with Electroconvulsive therapy (ECT) for depression, without The goal of medication management in such cases is to achieve adequate seizure (eg, 30 to 90 seconds) during ECT without causing spontaneous seizures. 4, 5 ECT is often delivered using brief pulse Methods: A MEDLINE search (1985-2006) was performed, using the terms "electroconvulsive therapy," "anticonvulsants," "epilepsy," "carbamazepine," "gabapentin," "lamotrigine," "topiramate," and "valproate," supplemented by manual searches of guidelines and textbooks on ECT. Conclusion: Gabapentin appears to be a promising adjunct during ECT to manage anxiety and myalgia as it did not interfere with seizure duration or clinical effect on depression. Although randomized, controlled trials must be performed; this case supports its use during ECT for these symptoms. Question from a Member: If a patient is on gabapentin and clonazepam, would they have to taper off of these to be able to start ECT? There are two main reasons why this question is clinically important. Electroconvulsive therapy (ECT) depends on the seizure threshold, so you don’t want to throw that off before starting it. Anticonvulsants and benzodiazepines are concerning, as are antidepressants. GABA Agonists Gabapentin, pregabalin 4 Glucocorticoids (systemic, inhaled) Budesonide, fluticasone, prednisone 5, 7 H 2 Receptor Blockers Cimetidine, famotidine, ranitidine 5 HMG-CoA Reductase Inhibitors Atorvastatin, rosuvastatin, simvastatin 4 Leukotriene Inhibitors Montelukast, zafirlukast 7 Mood Stabilizers Lithium, valproic acid 6 The procedure (ECT) Electroconvulsive Therapy (ECT) is a noninvasive brain stimulation technology. The ECT device delivers predetermined electrical pulses to the brain resulting in a controlled generalized seizure that exerts biological effects that translate into clinical benefit. You will need to temporarily stop taking the following medications before your surgery. These medications can thin your blood, change its clotting, and slow the healing process after surgery. Be aware: Many over-the-counter products may have some of these ingredients and must also be stopped. Despite many predictions that electroconvulsive therapy (ECT) would be replaced by pharmacotherapy, ECT has remained an invaluable adjunct in the management of severe psychiatric disease. Both pharmacotherapy and ECT continue to be used extensively, and will frequently be administered concurrently. Introduction. Several evidence-based documents on the use of electroconvulsive therapy (ECT) indicate that it is a safe and effective treatment for a variety of psychiatric disorders. 1–3 Although major depression refractory to antidepressant medications is the primary indication for ECT, there is also significant evidence to support its use in other psychiatric disorders such as catatonia PDF | On Jan 10, 2015, Stephanie Peglow and others published Use of Gabapentin during ECT for Myalgia and Anxiety: Effects on Seizure Activity | Find, read and cite all the research you need on Pre-ECT neurology consultations are often requested to determine the relative risk of the procedure in patients with neurological comorbidities, but there is limited data to guide clinicians. The authors performed a retrospective chart review of all consecutive inpatients at McLean Hospital who underwent a pre-ECT neurological evaluation between January 2012 and June 2014 (N=68). ECT was safe proceeding with therapy. Most literature regarding the use of use antiepileptic drugs in ECT focuses on antiepileptic mood stabilizers with which most psychiatrists are familiar. However, there is considerably less information available about the use of newer antiepileptics in conjunction with ECT, which may be prescribed to a patient with epilepsy or off-label for psychiatric reasons. Because of concerns that psychotropic medications, such as benzodiazepines and anticonvulsants, could adversely affect seizure threshold, seizure duration, and tolerability, clinicians question whether patients should discontinue these medications prior to electroconvulsive therapy (ECT). lsants," "epilepsy," "carbamazepine," "gabapentin," "lamotrigine," "topiramate," and "valproate," supplemented by manual searches of guidelines and textbooks on ECT. Results To date, no prospective, randomized and controlled trials examining outcome and safety of the AC-ECT combination have been published. Existing data are from case reports on the use of ECT for psychiatric conditions that Before ECT is performed, patients require a medical evaluation to undergo anesthesia, and some may need special consultation. Vagus nerve stimulation is the newest neuromodulatory technique to receive approval for adjunctive treatment of depression. Outside the scope of this chapter are drugs specifically given as part of ECT, or administered during the session to modify seizures, reduce the likelihood of adverse effects or affect clinical outcomes. Get access to the full version of this content by using one of the access options below. As such, all patients must be assessed prior to ECT for the presence of conditions such as cardiovascular disease, space-occupying intracranial lesion with the evidence of elevated intracranial pressure, recent cerebral hemorrhage or stroke, bleeding or otherwise unstable vascular aneurysm, and severe pulmonary disease, as all of these can be
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