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Gabapentin or pregabalin are compatible with breastfeeding, but should be used with caution and infant monitoring. They have low levels in breast milk and infant serum, and no adverse effects reported. Maternal doses of gabapentin up to 2.1 g/day produce relatively low levels in infant serum. A single oral dose of either 300 or 600 mg given to the mother before cesarean section appeared to have no effect on breastfeeding initiation. expert consensus indicates that gabapentin is an acceptable choice for refractory restless leg syndrome during lactation; Breast milk levels and infant absorption. gabapentin is a small molecule with low protein binding, which enables it to pass into breast milk; limited evidence shows gabapentin only transfers in small amounts Gabapentin (Neurontin) is a Pregnancy Category C medication that may cause fetal malformation and miscarriage. It is also excreted into breast milk and may affect the nursing infant, so breastfeeding women should consult their healthcare provider before taking it. • Kristensen JH, Ilett KF, Hackett LP, Kohan R, Gabapentin and breastfeeding: a case report, J Hum Lact, 2006;22:426–8. • Öhman I, Vitols S, Tomson T, Pharmacokinetics of gabapentin during delivery, in the neonatal period, and lactation: does a fetal accumulation occur during pregnancy? Epilepsia, 2005;46:1621–4. Gabapentin is a medication used to treat seizures, nerve pain, and restless legs syndrome. It enters breastmilk in low levels and has not been reported to cause side effects in infants. Breastfeeding while taking gabapentin: Gabapentin enters breastmilk in low levels. Blood tests on breastfed infants found low levels or levels too low to be detected. There are reports of infants exposed to gabapentin through breastmilk; no side effects were noted. A single oral dose of either 300 mg or 600 mg given to the mother before cesarean section appeared to have no effect on breastfeeding initiation. An expert consensus guideline indicates that gabapentin is an acceptable choice for refractory restless leg syndrome during lactation. The aim of this study was to describe the milk-plasma ratio and relative infant dose of gabapentin in a breastfeeding mother and to determine the well-being of her exposed infant. The mother-infant pair was studied over a 24-hour dose interval at steady state. The LactMed® database contains information on drugs and other chemicals to which breastfeeding mothers may be exposed. It includes information on the levels of such substances in breast milk and infant blood, and the possible adverse effects in the nursing infant. Gabapentinoids are medicines used to treat seizures and nerve pain. Gabapentinoids include gabapentin (Neurontin) and pregabalin (Lyrica). These medicines also may be used to treat ongoing pain or pain after procedures. Gabapentinoids are considered safe to use while breastfeeding. Gabapentin is a γ-aminobutyric acid analog formally indicated for the treatment of epilepsy and neuropathic pain that is gaining increased popularity. Gabapentin has been historically considered a safe medication, including during pregnancy and lactation, with low reported concerns for misuse and us Gabapentin may cause side effects such as dizziness, drowsiness, and dizziness. It is important to follow the prescribed dosage and seek medical attention if experiencing serious side effects or changes in mood or behavior. Gabapentin is prescribed by healthcare professionals and should only be taken under medical supervision. Gabapentin can be taken while breastfeeding, but it passes into breast milk in small amounts. There is no evidence of any side effects in breastfed babies, but talk to your doctor if you have any concerns. Background: The benefits of breastfeeding for both mother and infant are well documented. The World Health Organization recommends exclusive breastfeeding for the first four to six months of life Gabapentin Pregnancy and Breastfeeding Warnings. Brand names: Fanatrex, Gabarone, Gralise, Neurontin. Pregnancy Warnings; Breastfeeding Warnings; Gabapentin Pregnancy Warnings. Benefits should clearly outweigh risks AU TGA pregnancy category: B3 US FDA pregnancy category: Not assigned Kaufman KR, Struck PJ. Gabapentin-induced sexual dysfunction. Epilepsy Behav. 2011;21(3):324-6. Kristensen JH, Ilett KF, Hackett LP, et al. Gabapentin and breastfeeding: A case report. J Hum Lact. 2006;22:426–8. Loudin, S, et al. (2017). An Atypical Withdrawal Syndrome in Neonates Prenatally Exposed to Gabapentin and Opioids. Gabapentinand breastfeeding. gabapentin is considered compatible with breastfeeding, but should be used with caution and infant monitoring (1) published evidence for the use of gabapentin during breastfeeding is very limited. Data is from 10 mothers using gabapentin doses up to 2.1g daily Therefore, gabapentin, lamotrigine, oxcarbazepine, vigabatrin, tiagabine, pregabalin, leviracetam and topiramate are compatible with breastfeeding with a less documented safety profile. Ethosuximide, zonisamide and the continue use of clonazepam and diazepam are contraindicated during breastfeeding. Gabapentin is a drug used for neuropathic pain and seizure disorders. It has low levels in breastmilk and no reported adverse effects in breastfed infants.
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