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Veterinarians rated the cats that received gabapentin prior to the visit as friendlier and more docile. The owners reported that the maximum effect of the drug was 2–3 hours after administration. The timing of when to give your cat Gabapentin before a vet visit can vary depending on your cat's individual needs and the reason for the visit. However, in general, it is recommended to give your cat Gabapentin about 1-2 hours before the vet visit. At Just Cats, we like to have owners give the medication at home 2-3 hours prior to the vet visit, since that is typically the peak time for the drug’s effectiveness. However, every cat is different and occasionally we have to modify the dosage, timing, or even give a second dose. 2. Can I give my cat gabapentin the night before a vet visit? Yes, some cats benefit from receiving gabapentin the night before the vet visit, in addition to the dose given the day of the appointment. This can help reduce overall anxiety levels, especially in more stressed felines. Yes, giving gabapentin to your cat the night before a vet visit is generally considered safe and can be beneficial, particularly for anxious cats. Many veterinarians recommend this practice as part of a comprehensive sedation plan to minimize stress associated with veterinary appointments. In a recent study the efficacy of 20mg/kg gabapentin in hyperthyroid cats, given 1-2hrs before coming to the clinic, was evaluated. 6 This was a placebo-controlled study and the cats in the gabapentin group were significantly more relaxed during transport to the hospital, and more amendable to examination (exam, blood sampling, blood pressure). ANIMALS 20 healthy pet cats with a history of fractious behavior or signs of stress during veterinary examination. PROCEDURES Cats were scheduled for 2 veterinary visits 1 week apart and randomly assigned to receive a capsule containing 100 mg of gabapentin (13.0 to 29.4 mg/kg [5.9 to 13.4 mg/lb]) or placebo (lactose powder) prior to the first Van Haaften and coworkers at the College of Veterinary Medicine, University of California, Davis devised a random, blinded cross-over study of twenty healthy anxious and/or fractious cats to determine whether oral administration of a single 100-mg dose of gabapentin by cat owners prior to a veterinary visit would be effective at reducing Van Haaften et al. (2017) investigated the use of a single dose of gabapentin (100mg) in pet cats, administered before transport and a veterinary examination. Each cat had two clinic visits one week apart and received one of two treatments on each visit, gabapentin or a placebo. Based on pharmacokinetics, gabapentin may be given to dogs and cats to prevent fear or anxiety at veterinary visits at least 90 min before the visit. Some benefit has been anecdotally reported for some dogs of starting the gabapentin the evening before and the day of the veterinary visit, with the final dose coming 90 min before the appointment Oral gabapentin in cats – often without additional sedation/premedication – can be used by house-call and clinic-bound veterinarians to facilitate examination, blood draws, cystocentesis, blood glucose curves, ultrasound exams and additional injections. Frequently Asked Questions About Gabapentin for Cats 1. How long before a vet visit should I give my cat gabapentin? For anxiety and fear associated with veterinary visits, the typical recommendation is to give 100-200mg of gabapentin 2-3 hours prior to the appointment. Some vets may advise an additional dose the night before for particularly When gabapentin is given for a long time, the drowsiness effect wears off; if your kitty takes gabapentin regularly (for seizures, chronic pain, or other problems), a higher dose may be needed before the vet visit to achieve the same effect. A third study, published in a 2021 issue of JAVMA, found oral administration of gabapentin to cats 2 hours before a veterinary visit can reduce fear-aggression behavior during a physical examination. This study set out to investigate the effect of giving a single dose of gabapentin for fear-based aggressive behaviors in cats during veterinary cats (gabapentin for analgesia in cats = 5 – 10 mg/kg or 25 – 50 mg per cat, PO, BID) The use of pre-hospital gabapentin has been the single most effective tool for reducing fear and anxiety in healthy cats that I and many clinicians have used. Expect that cats will be ataxic and slow but not overtly sedate on this dose of gabapentin. Overall, the present study yielded good evidence that oral administration of a 100-mg gabapentin capsule to cats 90 minutes before transporting them to the veterinary hospital led to a significant reduction in stress-related behaviors during transportation and examination.
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