The fact that gabapentin was the number one prescription for feline musculoskeletal (MSK) pain in a survey on VIN is surprising, given we have NSAIDs and frunevetmab as licensed and effective options. In an unpublished study of cats undergoing ovariohysterectomy, gabapentin administered pre-operatively in combination with an opioid (buprenorphine) provided similar analgesia when compared with opioid + NSAID (buprenorphine + meloxicam) (Steagall 2016; personal communication). Gabapentin is usually used to manage chronic pain, especially nerve-related pain. It is also used (primarily in cats) to relieve anxiety associated with veterinary procedures, travel, and other fear-generating situations. Gabapentin can also be used as an additional medication in seizure management. Gabapentin is usually used to manage chronic pain, especially nerve-related pain. It is also used (primarily in cats) to relieve anxiety associated with veterinary procedures, travel, and other fear-generating situations. Gabapentin can also be used as an additional medication in seizure management. May 1, 2018. Amengual Batle P, Rusbridge C, Nuttall T, Heath S, Marioni-Henry K. Feline hyperaesthesia syndrome with self-trauma to the tail: retrospective study of seven cases and proposal for integrated multidisciplinary diagnostic approach. These (e.g., amitriptyline, dogs: 1–2 mg/kg orally q 12–24 h; cats: 2.5–12.5 mg/cat orally q 24 h, gabapentin [see above] may be beneficial as a home medication in combination with those listed above, as the descending inhibitory system appears to be dysfunctional in neuropathic states. In a 2017 quick poll by the Veterinary Information Network, an online community for the profession, 81% of 2,064 respondents said they prescribed gabapentin in some way for acute pain management. When the same poll question was asked in 2024, the number had risen to 93% of 2,779 respondents. The t ½ for gabapentin in dogs and cats is between 3 and 4 hrs. The recommended dose range of gabapentin for dogs is 25–60 mg/kg body weight, divided , q 6–8 hrs. I use an initial dose regimen of 10 mg/kg body weight, q 8 hrs. A 25-µg/hr patch can be applied to an "average" cat (3.5–5.0 kg). In smaller cats, other methods of providing analgesia should be sought as it is not recommended to cut patches in half and covering half of the patch gives unpredictable results. The decay in plasma levels following patch removal is slow. Gabapentin has many useful properties for treating cats beyond use as an anticonvulsant. It is used off-label in cats to reduce situational anxiety, provide pain relief, and is the preferred treatment for a condition called feline hyperesthesia syndrome. Gabapentin works by blocking the transmission of pain signals in the brain, providing relief for cats experiencing discomfort. Additionally, gabapentin can also be used to help calm anxious or stressed cats, making it a useful tool for veterinary professionals treating pets with behavior issues. During the first portion of the in vivo phase, transdermal gabapentin was applied to the ears or cervical skin of healthy cats at concentrations of 5 or 10 mg/kg every 8 hours. Eight cats were enrolled in this phase. In this VETgirl online veterinary continuing education podcast, we review the use of transdermal gabapentin in cats. I suspect many of you agree that giving gabapentin to fractious kitties prior to veterinary appointments has been an absolute game changer! Each cat should have the opportunity to play with the owner or with another cat if desired. Each cat should be able to move freely about its home, including climbing if desired. Scratching posts should be available. Toys should be regularly rotated/replaced. Each cat should be able to choose warmer and cooler areas within the home. Gabapentin is usually used to manage chronic pain, especially nerve-related pain. It is also used (primarily in cats) to relieve anxiety associated with veterinary procedures, travel, and other fear-generating situations. Gabapentin can also be used as an additional medication in seizure management. In cats, gabapentin is most often used as a pain medication for chronic pain, such as from arthritis. Gabapentin is also recognized as beneficial in reducing the fear responses that a kitty may have to the stress of handling and being examined at the vet. Gabapentin is used in cats to treat chronic pain, especially of neuropathic origin and anxiety. For pain, this drug seems to be most effective when combined with other types of analgesics (for Trazodone + clonidine + gabapentin Trazodone + acepromazine + gabapentin *Lorazepam can be added to any of the above combinations in non-fractious patients. All are safe premeds for injectable sedation in healthy dogs. Oral premed cocktails for cats: Lorazepam + acepromazine Acepromazine + gabapentin Lorazepam + gabapentin. Chemical Restraint For mild to moderate fear and anxiety in dogs, trazodone, clonidine, benzodiazepines (e.g. alprazolam, diazepam, lorazepam), gabapentin, imepitoin or dexmedetomidine oromucosal gel might be effective for car ride anxiety, veterinary visits and procedures. 3 In cats, gabapentin, trazodone and benzodiazepines (e.g. lorazepam, alprazolam) can be One study of long-term use of gabapentin as an adjunct drug in 3 cats with chronic pain (average dose 6.5 mg/kg BID) concluded that satisfactory pain management was achieved. Polysulfated glycosaminoglycan (Adequan) is said to have both chondroprotection and chondrostimulation properties.
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