gabapentin cause water retention gabapentin review article

1. Does gabapentin cause water retention in the legs? Yes, gabapentin is associated with peripheral edema, leading to fluid retention and swelling in the legs and feet. The risk is generally considered dose-related and more common in elderly patients. 2. How long does gabapentin edema last? The cause of weight gain with gabapentin is likely due to increased appetite. You may be hungry more often. In some cases, weight gain may be due to fluid retention, another side effect of gabapentin. Another possible cause is not getting enough exercise if gabapentin is causing fatigue. Some ways to avoid weight gain include: This study helps us to admit the point that switching brand of gabapentin could cause new side-effects. It is necessary that the physicians know the side-effects of drugs such as gabapentin and notice that an anti-analgesic drug can cause pain too. Background Gabapentin and pregabalin are commonly prescribed medications to treat pain in patients with diabetic neuropathy. Gabapentin and pregabalin can cause fluid retention, which is hypothesized to be associated with cardiovascular diseases. However, whether long-term use of gabapentin and pregabalin is associated with adverse cardiovascular diseases remains unknown. This study aims to Gabapentin may cause weight gain by increasing your appetite, causing fluid retention, and inhibiting physical activity by causing fatigue. Because gabapentin is an anticonvulsant, it prevents seizures and nerve pain by reducing nerve activity in the central nervous system. Gabapentin (Neurontin) is a medication that’s FDA approved to treat seizures and postherpetic neuralgia (nerve pain from shingles). Gabapentin can cause fluid buildup in the legs (edema), which can lead to temporary weight gain. You can also gain weight without fluid buildup, though it’s not common. Background. Gabapentin binds to the alpha-2-delta subunit of presynaptic voltage-gated calcium channels and is used for a wide variety of indications both Food and Drug Administration approved and off-label. 1-3 It is approved by the Food and Drug Administration to treat postherpetic neuralgia and epilepsy 4 with common off-label indications including fibromyalgia, anxiety, mood disorders, and Gabapentin and pregabalin can cause fluid retention, which is hypothesized to be associated with cardiovascular diseases. However, whether long-term use of gabapentin and pregabalin is associated with adverse cardiovascular diseases remains unknown. Edema is a well-described side effect of gabapentinoid drugs (i.e., gabapentin and pregabalin). In this study from Ontario, Canada, researchers used provincial databases to examine whether gabapentinoid use was followed by diuretic prescriptions — a so-called “prescribing cascade” in which a drug is prescribed to treat an adverse effect of another drug. All cases of peripheral edema or heart failure [Medical Dictionary for Regulatory Activities (MedDRA) Hight-Level Term ‘total volume fluid increased’ or High-Level Group Term ‘heart failures’] involving gabapentin or pregabalin and recorded between January 1, 1994 and April 30, 2020 were selected. Fluid retention, or edema, can occur when gabapentin affects vascular permeability or alters kidney function. Edema refers to swelling caused by excess fluid accumulation in tissues. It can occur in various parts of the body but is most commonly seen in the legs, ankles, and feet. Gabapentin is a medication used to treat seizures, restless legs syndrome, and nerve pain from shingles. Some people taking it report fluid retention and swelling in their extremities. Swelling may be more likely if you’re older, or if you’re taking a higher gabapentin dosage. Gabapentin side effects are usually mild, and they may be less common with gabapentin ER forms. Examples of mild side effects that can happen include: Vertigo (dizziness) Feeling fatigued or sleepy. Fluid retention. Trouble balancing or controlling movement. Diarrhea or constipation. Nausea and vomiting. Brain fog. Headache. Weight gain. Dry mouth Studies have suggested that gabapentin may interfere with the RAS, leading to an imbalance in fluid regulation. Increased fluid retention can cause edema in certain individuals receiving gabapentin therapy. Indirect Mechanisms Hello! I have been on Gabapentin for Neuropathic back pain only for one month and am at the max dose of 3600 mg a day. It is helping with the pain however I am seeing the water retention. I work out daily and my clothes fit tighter and I can see swelling in my legs and abdominal bloat. Common side effects of gabapentin include: flulike symptoms such as fever or body aches. Rare but serious side effects of gabapentin include: changes in memory, ability to concentrate, or personality. Gabapentin may cause breathing problems in people who use opioid pain medicines and those with chronic obstructive pulmonary disease (COPD). One common reason for swelling is fluid retention. Gabapentin can cause changes in kidney function or fluid balance in the body. When the body retains excess fluid, it can lead to noticeable swelling in areas like the legs, ankles, or hands. Gabapentin and pregabalin can cause fluid retention, which is hypothesized to be associated with cardiovascular diseases. However, whether long-term use of gabapentin and pregabalin is associated with adverse cardiovascular diseases remains unknown. Does gabapentin cause fluid retention? Yes, gabapentin may cause fluid retention and induce edema in arms and legs. Experts believe that this side effect can also be the reason for weight gain by increasing your water weight. Gabapentin does help with the pain but, I don’t like the swelling. It also makes me drowsy but I sleep good. The drug has pros and cons about it. I have been on it for about 8.5 years with no fluid retention or other side effects. Thanks for your response but Im not 100% convinced that is true.

gabapentin cause water retention gabapentin review article
Rating 5 stars - 446 reviews




Blog

Articles and news, personal stories, interviews with experts.

Video