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Sedation is the main potential side effect of gabapentin, and the level of sleepiness varies from patient to patient. Veterinarians will prescribe a starting dose, and if this results in the dog becoming a little too sedate, the veterinarian will taper the dose down to the most effective one. 9. Are there any contraindications for using gabapentin in dogs? Gabapentin should not be used in dogs with a known allergy to the medication. It should also be used with caution in dogs with liver or kidney problems, as gabapentin is metabolized by the liver and excreted by the kidneys. 10. Gabapentin is a contraindicated drug for dogs with hypersensitivity or allergy to the drug or any of its excipients. It should also be used with caution in dogs with liver or kidney failure or disease. Gabapentin The medicine you have been given for your dog or cat is called gabapentin. It may have a trade name such as Neurontin®, but often will just be called gabapentin. What is gabapentin? Gabapentin belongs to a group of medicines that are called anti-epileptics. These drugs act on the brain to prevent epileptic seizures (fits). Some anti- Are there any contraindications for Gabapentin use in dogs? Gabapentin should not be used in dogs with a known allergy to the medication or in pregnant or nursing animals, unless deemed necessary by a veterinarian. Overall, gabapentin is safe for dogs, but it’s important to follow certain precautions. Never give your dog liquid gabapentin made for humans. The reason isn’t the gabapentin, but the xylitol Common Contraindications and Warnings Some human preparations contain xylitol which is highly toxic to dogs and cats. Potential Side Effects Administration Instructions/Handling Storage Speed of Action, Duration of Effect + Monitoring When long-term treatment is no longer needed, treatment should be stopped slowly. Veterinary use of gabapentin has increased dramatically over the past several years, probably as an oral analgesic alternative to non-steroidal anti-inflammatory drugs (NSAIDs) and as a result of the lack of evidence for the analgesic effects of tramadol in some species, particularly dogs (Davila et al. 2013; KuKanich 2013; Donati et al. 2021). Targeted Use of Gabapentin. One of the most commonly cited uses of gabapentin in veterinary medicine is for treating acute post-operative pain. 5 Considering the mechanism of action of gabapentin and its impact on pain signaling, it is unlikely that gabapentin will be an effective analgesic in this context. Inflammation is the most common Gabapentin is not safe for use in pregnancy but should be safe for use in lactation. Gabapentin should not be abruptly discontinued after long-term use as seizures can be precipitated. Instead, gabapentin should be gradually tapered off over a couple of weeks. Veterinary studies of the use of this drug are limited. Sudden withdrawal should be avoided. Dose should be decreased gradually over 1 week if discontinuing use when treating seizures. Gabapentin should be USED WITH CAUTION in pets that: Do not stop this medication abruptly in pets with epilepsy, as this can cause withdrawal seizures. Some liquid oral formulations contain xylitol, a sugar substitute that is toxic to dogs, so be cautious and read the label before administering. Dogs and Cats.1,2 The 2015 guidelines differ from the earlier version in several ways. The first sections are general concepts designed to Tablets, capsules, oral solution. Oral solutions of gabapentin can contain xylitol, which is toxic to dogs. Be cautious and read the label before administering. Never give any medication to dogs that contain xylitol as an ingredient. 5. Drug Type/Class: Anticonvulsant, other: GABA analog. 6. Uses in Dogs and Cats: Concern #10: Are there any contraindications to using gabapentin in dogs? Answer: Gabapentin should be used with caution in dogs with kidney disease, as it is primarily excreted through the kidneys. Your veterinarian may adjust the dosage of gabapentin or monitor your dog's kidney function more closely when using gabapentin in these cases. FULL PRESCRIBING INFORMATION . 1 INDICATIONS AND USAGE . NEURONTIN. is indicated for: • Management of postherpetic neuralgia in adults • Adjunctive therapy in the treatment of partial onset seizures, with and without secondary One of the benefits of gabapentin is that many dogs experience no side effects or only mild transient side effects. The three most common potential side effects listed in the drug handbooks (and corroborated by my personal experience) are sedation, loss of coordination, and GI upset. Let’s take a look at each side effect in more detail. the veterinary community should closely scrutinize where gabapentin fits into our “analgesic toolbox,” gabapentin should not be prescribed for conditions where it is unlikely to be effective. Additionally, veterinary practitioners should consider limiting the number of drugs dispensed and placing restrictions on refill authorizations. However, in dogs, gabapentin showed favourable effects in the treatment of epilepsy [10, 11], chronic, neuropathic and post-operative pain, [12, 13, 14] and anxiety [15, 16]. In cats, it showed efficacy in post-ovariohysterectomy-related pain [17, 18] and in anxiety management [19, 20, 21, 22]. Gabapentin achieves a steady state within 1-2 days. Is Gabapentin a Strong Painkiller for Dogs? Gabapentin is a drug used successfully by veterinarians in treating chronic and nerve pain. It has far fewer side effects than NSAIDs, which in the long run, can become dangerous for pets.
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