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In the case of gabapentin, it is the opposite. While gabapentin is NOT considered as a controlled substance on a federal level, there are some states that reclassified the drug as a controlled substance. The five states that have reclassified gabapentin as a controlled substance are Kentucky, Virginia, West Virginia, Michigan, and Tennessee. Gabapentin isn’t a narcotic or federally controlled substance, but it is regulated and recognized as a controlled substance in certain states. Gabapentin is approved by the Food and While gabapentin remains a non-controlled substance, Session Law 2023-65 Part XI Section 11.1 G.S. 90-113.73(b) adds it to the medications recorded in NC CSRS because it may cause a level of sedation in patients that puts them at increased risk of overdose when taken with opioids. The NC Department of Health and Human Services (NCDHHS) has Gabapentin is not currently listed as a controlled substance under the Controlled Substances Act of 1970. Individuals at the highest risk for abusing gabapentin include those with opioid abuse, mental illness, or previous history of prescription drug abuse. The prevalence of gabapentin abuse has been estimated to be 1.6% in the general population compared with 15% to 22% in patients with opioid use disorders. 23 Individuals with a history of substance abuse (particularly opioids) or mental illness have been identified as having an increased risk of abusing gabapentin. 23 Evidence of gabapentin abuse was observed in a group of 503 individuals in Twelve states have not classified gabapentin as a controlled substance, but require gabapentin dispensing must be reported to their PMP (including CT, DC, IN, KS, MA, MN, NE, NJ, OH, OR, UT, and WY). At the federal level, gabapentin is not classified as a controlled substance, is regarded as a non-addictive medication, and is recognized by the Centers for Disease Control and Prevention (CDC) as a potential substitute for opioids in managing chronic pain. Gabapentin isn’t a controlled substance according to the federal government. But several states have passed their own laws classifying gabapentin a schedule V (schedule 5) controlled substance. Combining gabapentin and opioids can be extremely dangerous. Gabapentin isn’t a controlled substance or narcotic on the federal level, but several states have passed laws to make it a Schedule V controlled substance. Gabapentin has risks and adverse effects, especially when combined with some other substances. Gabapentin (Neurontin) is not a narcotic or federally controlled substance by the DEA as of November 2022, but it is classified as a Schedule V controlled substance in certain states. Gabapentin is frequently combined with other substances for the purpose of potentiating the effects of the drugs or achieving a “high.” Studies have identified various substances that are commonly abused in combination with gabapentin, including alcohol, opioids, benzodiazepines, antidepressants, and other CNS depressants 13,14,15. At the national level, gabapentin is not classified as a controlled substance under the Controlled Substances Act (CSA). This means it is not subject to the stringent regulations that apply to opioids or benzodiazepines, which are categorized based on their potential for abuse, medical use, and safety. Gabapentin is not a controlled substance on a federal level but is controlled in some states, which limits the number of prescription refills and how it is reported. Gabapentin can be dangerous when used in combination with other substances, particularly opioids. Gabapentin closely resembles pregabalin, a schedule V drug under the Controlled Substances Act in its chemical structure and pharmacological activity. The chemical structure of gabapentin is derived from the addition of a lipophilic cyclohexyl group to the backbone of GABA. At the federal level, gabapentin is not classified as a controlled substance, is regarded as a non-addictive medication, and is recognized by the Centers for Disease Control and Prevention (CDC) as a potential substitute for opioids in managing chronic pain. However, growing concerns about the potential for misuse are increasing. Several US In the state of Kentucky, prescribers without a DEA license are unable to prescribe gabapentin after it was classified as a Schedule V controlled substance. 38 This licensing requirement is part of the state’s Controlled Substances Act which had the greatest impact on mid-level practitioners who may not have a DEA license. Kentucky Schedule-V controlled substance and mandated reporting to PDMP. The State of Kentucky is, and to date, remains, the only state to have reclassified gabapentin as a Schedule-V controlled substance. 21 Effective July 1, 2017, the prescribing of gabapentin is limited to authorized practitioners, defined as practitioners registered with the US DEA. 21 Thus, mid-level practitioners, specifically CFR §1300.01 (Defintions relating to controlled substances). Androstanedione (5alpha-androstan-3,17-dione) 4000; III N ; Aprobarbital 2100 III; N Alurate ; Barbital 2145; III N ; Veronal, Plexonal, barbitone Schedule III in KY (902 KAR 55:015). Schedule IV federally. Barbituric acid derivative 2100; III N ; Barbiturates not specifically listed , any new orders for Gabapentin issued by a practitioner WITHOUT a Utah. Controlled Substance license and a DEA registration will not be valid and MAY NOT be administered or dispensed. Prescription orders (including refills) issued for Gabapentin prior to May 1 , 2024, will not be. aected. It is not legal to distribute Gabapentin samples in Utah.
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