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Drug Interaction Classification; These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication. Major: Highly clinically significant. Some vitamins and dietary supplements interact with medicines, too. Drug-condition interaction. This is when you have a health problem that makes it risky for you to take certain meds. For Some of the main substances that interact with gabapentin are morphine, caffeine, losartan, ethacrynic acid, phenytoin, mefloquine and magnesium oxide. Some of the side effects caused by gabapentin are teratogenicity, hypoventilation, respiratory failure and myopathy. Amlodipine Interactions. There are 535 drugs known to interact with amlodipine, along with 4 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 23 are major, 474 are moderate, and 38 are minor. Comprehensive alcohol & food interactions for Neurontin (gabapentin). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. There is 1 alcohol/food/lifestyle interaction with gabapentin. Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with gabapentin. In order to prevent this drug interaction, patients are advised to delay administration of gabapentin to at least 2 hours after taking the antacid. Diagnostic Test Aside from these medications, gabapentin can also cause false positive readings in the patient’s dipstick test for urinary protein. Gabapentin enacarbil (brand name Horizant), a prodrug of gabapentin, is rapidly absorbed by nutrient transporters along the gastrointestinal tract and then quickly hydrolyzed to gabapentin. This means gabapentin enacarbil only needs to be given once a day. Nutrient interactions associated with common pharmaceuticals The chart below primarily includes drug-nutrient interactions for which evidence from systematic reviews, meta-analyses, and randomized, double-blind, placebo-controlled human trials was available. See the white paper for a full review of literature on Gabapentin is in the drug class gamma-aminobutyric acid analogs. A total of 17 drugs are known to interact with Vitamins. Vitamins is in the drug class vitamin and mineral combinations. Vitamins is used to treat Dietary Supplementation. There are no specific foods to avoid while taking gabapentin in terms of drug/food interactions. However, if you’re taking gabapentin for seizures or nerve pain, a general, anti-inflammatory diet is recommended to support nerve and overall health. Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with gabapentin. There are 4 disease interactions with gabapentin. Major Potential Hazard, Moderate plausibility. Applicable conditions: Drug Abuse/Dependence. Anxiolytic, sedative, and hypnotic agents have the potential to cause dependence and abuse. The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. Drug-food and drug-drink interactions: Food and drinks can change how medicines work or worsen side effects when they are combined. Examples include beverages like grapefruit juice and statins causing muscle pain, or alcohol and opioids leading to dangerously slowed breathing. Gabapentin, like any other substance, can interact with other substances. Those taking gabapentin should therefore always disclose to their doctors any medical conditions, other medications (prescription or over the counter), supplements, herbal products, illicit drugs, tobacco products, alcoholic beverages, and dietary choices. Generic Name Gabapentin DrugBank Accession Number DB00996 Background. Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid that was first approved for use in the United States in 1993. 16 It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures 14,5 - today it is also widely used to treat neuropathic pain. 8 Gabapentin is approved to prevent and control partial seizures, relieve postherpetic neuralgia after shingles and moderate-to-severe restless legs syndrome. Learn what side effects to watch for, drugs to avoid while taking gabapentin, how to take gabapentin and other important questions and answers.
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