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Breastfeeding while taking gabapentin: Gabapentin enters breastmilk in low levels. Blood tests on breastfed infants found low levels or levels too low to be detected. There are reports of infants exposed to gabapentin through breastmilk; no side effects were noted. Can Breastfeeding Women Take Gabapentin? Gabapentin is excreted into the breast milk in women. It is believed that the nursing infant may be exposed to a maximum dose of approximately 1 mg/kg per day of gabapentin. Selected References: Blotiere PO, et al. 2020. Risk of early neurodevelopmental outcomes associated with prenatal exposure to the antiepileptic drugs most commonly used during pregnancy: a French nationwide population-based cohort study. BMJ Open 10(6). Brannon GE, Rolland PD. Anorgasmia in a patient with bipolar disorder type 1 treated with gabapentin. J Clin Psychopharmacol. 2000;20(3):379 Three infants who were 2 to 3 weeks of age and one who was 14 weeks of age were breastfed during maternal use of gabapentin in an average daily dosages of 1575 mg (range 600 mg to 2.1 grams daily). Serum levels were measured after the morning nursing before the mothers' morning dose of gabapentin (10 to 15 hours after the prior evening's dose). Breastfeeding while taking gabapentin: Gabapentin enters breastmilk in low levels. Blood tests on breastfed infants found low levels or levels too low to be detected. Certain medicines when used while breastfeeding may cause harm or unwanted side effects in the baby. Some medicines may affect breast milk production or supply. It is important that you talk to your healthcare team before starting, stopping or changing medicines while breastfeeding. Whether medicine affects the baby during breastfeeding depends on: Gabapentin January 1, 2024 page 1 of 2 Gabapentin This sheet is about exposure to gabapentin in pregnancy and while breastfeeding. This information is based on available published literature. It should not take the place of medical care and advice from your healthcare provider. What is gabapentin? A single oral dose of either 300 mg or 600 mg given to the mother before cesarean section appeared to have no effect on breastfeeding initiation.[1] An expert consensus guideline indicates that gabapentin is an acceptable choice for refractory restless leg syndrome during lactation.[2] Gabapentinand breastfeeding. gabapentin is considered compatible with breastfeeding, but should be used with caution and infant monitoring (1) published evidence for the use of gabapentin during breastfeeding is very limited. Data is from 10 mothers using gabapentin doses up to 2.1g daily DrLact safety Score for Gabapentin is 1 out of 8 which is considered Safe as per our analyses. A safety Score of 1 indicates that usage of Gabapentin is mostly safe during lactation for breastfed baby. Our study of different scientific research also indicates that Gabapentin does not cause any serious side effects in breastfeeding mothers. gabapentin is considered compatible with breastfeeding, but should be used with caution and infant monitoring (1) published evidence for the use of gabapentin during breastfeeding is very limited. Data is from 10 mothers using gabapentin doses up to 2.1g daily This article summarizes the current literature regarding gabapentin use during pregnancy and related prenatal and neonatal exposure outcomes with special consideration for interactions between gabapentin and opioid use. Therefore, gabapentin, lamotrigine, oxcarbazepine, vigabatrin, tiagabine, pregabalin, leviracetam and topiramate are compatible with breastfeeding with a less documented safety profile. Ethosuximide, zonisamide and the continue use of clonazepam and diazepam are contraindicated during breastfeeding. Most antiepileptic drugs that have breastfeeding information reported appear to be acceptable to use during breastfeeding as single agents. Long-term follow-up data indicate that maternal carbamazepine, lamotrigine, phenytoin, and valproate cause no long-term developmental problems in breastfed infants. If your doctor or health visitor says your baby is healthy, you can take gabapentin while breastfeeding. It's important to keep taking gabapentin to keep you well. Gabapentin passes into breast milk in small amounts. It has not been known to cause any side effects in breastfed babies. With maternal doses up to 2.1 g/day, estimated doses for fully breastfed infants are 0.2 to 1.3 mg/kg/day (equivalent to 1.3 to 3.8% of the maternal weight-adjusted dose). An expert panel has deemed this drug is an acceptable choice for refractory restless leg syndrome during lactation. Results: The literature review produced 183 original articles for evaluation, which revealed data for 62 of the 96 psychotropic drugs. The remaining 34 medications had no data (including from the • Kristensen JH, Ilett KF, Hackett LP, Kohan R, Gabapentin and breastfeeding: a case report, J Hum Lact, 2006;22:426–8. • Öhman I, Vitols S, Tomson T, Pharmacokinetics of gabapentin during delivery, in the neonatal period, and lactation: does a fetal accumulation occur during pregnancy? Epilepsia, 2005;46:1621–4. Gabapentin is considered compatible with breastfeeding, but should be used with caution and infant monitoring. Published evidence for the use of gabapentin during breastfeeding is very limited. Data is from 10 mothers using gabapentin doses up to 2.1g daily. Gabapentin January 1, 2024 page 1 of 2 Gabapentin This sheet is about exposure to gabapentin in pregnancy and while breastfeeding. This information is based on available published literature. It should not take the place of medical care and advice from your healthcare provider. What is gabapentin?
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