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Gabapentin is well absorbed from the duodenum in dogs with maximum blood levels reached in 1 hour after oral administration. The elimination half-life of gabapentin in dogs is 3-4 hours in dogs, meaning that it may be difficult to attain steady state levels in dogs even with tid dosing. In dogs, gabapentin was useful in the treatment of epilepsy, as well as chronic, neuropathic, and post-operative pain and anxiety. In cats, it was effective in post-ovariohysterectomy-related pain and in the management of anxiety. In horses, it has been administered as an analgesic for chronic pain. According to pet experts and veterinarians, the safe dose of gabapentin for treating seizures in cats is 2-5mg/lb or 5-10mg/kg every 8 to 12 hours. For feline pain, the ideal amount of the medicine is 1.25 to 2 mg/kg every 12 hours. In dogs, gabapentin was beneficial in the treatment of epilepsy, as well as chronic, neuropathic, and post-operative pain, as well as anxiety. In cats, it showed efficacy in post-ovariohysterectomy-related pain and in anxiety management. Gabapentin for dogs is commonly prescribed for pain, anxiety, or seizures. It's generally safe, but there are some known side effects to be aware of. Gabapentin does have some anti-seizure effects, but it is not considered a first-choice option for seizure disorders in cats. Other medications are typically prescribed first to control seizures. Gabapentin may be used in cats as add-on therapy. Cats with primary epilepsy tend to experience their first seizure at a young adult age. This is an uncommon cause of seizures in cats. Secondary epilepsy means there is a structural disease in the brain - for example, a brain tumour, inflammation or infection of the brain (encephalitis), or a recent or previous stroke or head trauma. A 2005 study investigated gabapentin as an add-on anticonvulsant in dogs with refractory seizures and found that in a 4-month period, 3 of 17 dogs were seizure-free and 4 other dogs had a 50% reduction in seizure frequency. 11 epileptic dogs (refractory to phenobarbital and KBr) treated with gabapentin at 10mg/kg every eight hours. The frequency of seizures was estimated from the owners’ seizure diaries during the three months before and after treatment with gabapentin began. Six out of 11 dogs had a reduction Medications such as chlorazepate, pregabalin, and gabapentin have not been well-studied in cats for their anticonvulsant properties. Some veterinarians do use them to control seizures, especially as an add-on treatment in cats who are still having seizures while on another anticonvulsant. The effects of gabapentin on cats can vary depending on the dosage, the cat’s individual health, and the reason for its prescription. In general, gabapentin is used in cats to manage pain, anxiety, and seizures. Treating seizures: For controlling epilepsy, gabapentin is used with other anticonvulsants, offering an additional layer of seizure management for affected cats. Reducing anxiety and stress: It significantly reduces anxiety and stress, making stressful situations like vet visits more manageable for cats, leading to a smoother and less fearful A minimum 50 per cent reduction in the number of seizures per week was interpreted as a positive response to gabapentin, and six of the dogs showed a positive response. After the addition of gabapentin, both the number of seizures per week (P= 0.005) and the number of days with any seizures in a one-week period (P=0.03) were significantly reduced. Brand Name: Neurontin. Available in 100 mg, 300 mg, and 400 mg capsules; 600 mg and 800 mg tablets; and oral solution (some products not appropriate for dogs) Background. Gabapentin was originally approved to treat epilepsy in humans. However, gabapentin became more useful as a drug to control nerve pain. In cats, gabapentin is most often used as a pain medication for chronic pain, such as from arthritis. Gabapentin is also recognized as beneficial in reducing the fear responses that a kitty may have to the stress of handling and being examined at the vet. Veterinarians commonly prescribe gabapentin to treat pain, seizures, and anxiety in dogs. Gabapentin is a human medication, and its use in veterinary medicine is “off-label,” meaning it is not FDA-approved for pets. Sedation is the main potential side effect of gabapentin, and the level of sleepiness varies from patient to patient.
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