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Bar Ad V. Gabapentin for the treatment of cancer-related pain syndromes. Rev Recent Clin Trials 2010; 5(3):174-178. Caraceni A, Zecca E, Bonezzi C, et al. Gabapentin for neuropathic cancer pain: A randomized controlled trial from the Gabapentin Cancer Pain Study Group. J Clin Oncol 2004; 22(14):2909-2917. Several case reports note analgesia when gabapentin was used for treatment of chronic pain. 14,15 And in a clinical study on postoperative pain in dogs undergoing mastectomy, although pain scores did not differ, dogs receiving NSAIDs plus gabapentin required fewer opioid rescue doses than dogs receiving NSAIDs alone; thus, the gabapentin did Table 2. Principal Opioids Used to Treat Cancer Pain in Dogs and Cats . The standard opioid remains morphine, a pure mu-receptor agonist. Morphine is relatively inexpensive, has predictable and tolerable side effects, and can be administered by various routes (subcutaneous, intramuscular, intravenous, oral, epidural). Use of Nerve Blocks. In humans, cancer pain management frequently includes nerve blocks, in which analgesic is injected into or around a nerve or into the spinal cord to block pain; nerves may also be transected surgically to relieve cancer pain. 1 These modalities have not been used routinely in veterinary patients but may be worth exploring when other options are limited. Gabapentin is an anti-epileptic and analgesic drug originally intended to be a centrally acting gamma-aminobutyric acid (GABA)-receptor agonist. 1 Gabapentin is currently labeled by the FDA for use in humans as an anticonvulsant and for treating pain associated with spinal cord injuries, fibromyalgia, post-herpetic neuralgia, and neuropathic Gabapentin offers a versatile solution for managing pain and anxiety, aiding behaviors like stress during vet visits or nerve-related pain from conditions like cancer. Learn about its uses, proper dosage, potential side effects, and essential tips for giving it to your feline companion. It is likely to be particularly useful in cancer pain where there is a significant inflammatory component. Tramadol 4–6 mg/kg PO q 8–12 hrs. Analgesics for Chronic Pain in Cats Amantadine 3.0 mg/kg PO q 24 hr Gabapentin is a versatile medication prescribed for cats to manage pain, anxiety, and seizures Key Takeaways: Quick Answers About Gabapentin for Cats 📝 What is gabapentin used for in cats? Pain relief, anxiety reduction, and seizure control. What is the standard dosage?💊 5-40 mg/kg depending on the condition. Can gabapentin cause side effects?🚨 Yes, sedation Gabapentin can reduce chronic pain caused by conditions such as arthritis or cancer. It may be used to treat pain associated with intervertebral disk disease. Gabapentin is commonly used as a mild sedative to treat situational anxiety, for example, just before a vet visit, or for cats who are fearful around people or other animals. Gabapentin is a non-opioid pain reliever sometimes prescribed for cats with chronic pain from cancer and cancer treatments. Consult with your veterinarian about the drug and make sure to get a compounded version of the medication, which is Although gabapentin is typically well-tolerated, many veterinary professionals use caution when prescribing it for cats with kidney disease. Because it is not a narcotic or NSAID, gabapentin may be prescribed along with narcotic pain relievers or NSAIDs to manage pain after cancer surgery for cats. Things to Consider When Administering Gabapentin In cats, gabapentin is most often used as a pain medication for chronic pain, such as from arthritis. Gabapentin is also recognized as beneficial in reducing the fear responses that a kitty may have to the stress of handling and being examined at the vet. Gabapentin Anticonvulsant • 5–10 mg/kg PO Q 8–12 H Prednisolone Glucocorticoid • 0.5–1 mg/kg PO Q 24 H *Use of meloxicam oral suspension in cats is extra-label; † Approved for short-term use in cat≥.5 lb (2.5 kg) an≥ In addition to pain and stress, gabapentin for cats can also be used to treat seizures, cancer pain, and feline hyperesthesia syndrome. Pain is an unfortunate but highly prevalent burden associated with cancer in veterinary patients. The mechanisms by which cancer can cause pain are numerous but generally include direct tumor effects such as tissue damage, compression, or invasion by neoplastic growth; and indirect effects caused by paraneoplastic mediators (such as in hypertrophic osteopathy). Gabapentin. Gabapentin, an anticonvulsant drug, is used in cats as an adjunct for chronic pain management, especially neuropathic pain; it has been used in combination with opioids, NSAIDs, and amantadine. This drug can prevent allodynia (sensation of pain from nonnoxious stimulus) and hyperalgesia (increased sensitivity to pain response).
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