Selection criteria: Randomised, double-blind studies reporting the analgesic and adverse effects of gabapentin in neuropathic pain or fibromyalgia with assessment of pain intensity, pain relief, or both, using validated scales. Participants were adults. Research on gabapentin for fibromyalgia is mixed, but some people find it helps to relieve symptoms like widespread pain and insomnia. This article discusses gabapentin for fibromyalgia, including dosage and side effects. Gabapentin is an antiepileptic drug widely licensed for treatment of neuropathic pain. It is not licensed for the treatment of fibromyalgia, but is commonly used because fibromyalgia can respond to the same medicines as neuropathic pain. It has now been repurposed for off-label use to treat fibromyalgia pain. In this article, we look at gabapentin for fibromyalgia, the clinical studies that have been conducted, how it is effective in fibromyalgia treatment, and the potential side effects. One, from the National Institute for Health and Care Excellence in the United Kingdom, includes the use of gabapentin as a first-tier treatment for all neuropathic pain.14 Similarly, the European Federation of Neurological Societies includes gabapentin as a first-tier agent in its guideline for neuropathic pain, specifically including painful There is insufficient evidence to support or refute the suggestion that gabapentin reduces pain in fibromyalgia, and the evidence is very uncertain about estimates of benefit and harm. BACKGROUND This review replaces part of an earlier review that evaluated gabapentin for both neuropathic pain and fibromyalgia, now split into separate reviews for the two conditions. This review will consider Selection criteria: Randomised, double-blind studies reporting the analgesic and adverse effects of gabapentin in neuropathic pain with assessment of pain intensity and/or pain relief, using validated scales. Participants were adults aged 18 and over. Data collection and analysis: Two review authors independently extracted data. We calculated Randomised, double-blind trials of eight weeks' duration or longer for treating fibromyalgia pain in adults, comparing gabapentin with placebo or an active comparator. Gabapentin for pain in adults with fibromyalgia. Bottom Line. There is no good evidence to support or contradict the suggestion that gabapentin at daily doses of 1200 to 2400 mg reduces pain in fibromyalgia. Background. Fibromyalgia is a complex disorder characterised by widespread pain, fatigue, poor sleep, low mood, and other bodily symptoms. In May 2016 we searched for clinical trials where gabapentin was used to treat pain due to fibromyalgia in adults. We found one study that met the requirements for this review. The study tested 1200 to 2400 mg/day of gabapentin compared with a placebo over 12 weeks, in 150 people. Gabapentin, a generic for Neurontin, is frequently prescribed for fibromyalgia. This drug has been shown to reduce pain, but it does have a number of drawbacks. I’ve been on gabapentin for over two years and it does provide some relief, but I’m concerned about the side effects. The rationale behind its use is based on the types of pain that OA causes, namely nociceptive pain (pain caused by damage to tissues) and nociplastic pain (pain caused by altered sensory perception). Fibromyalgia is the main example of nociplastic pain, the condition of which is responsive to drugs like gabapentin. This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the analgesic efficacy of gabapentin for fibromyalgia pain in adults and the adverse events Gabapentin for chronic neuropathic pain and fibromyalgia in adults. Neuropathic pain is pain coming from damaged nerves. It differs from pain messages carried along healthy nerves from damaged tissue (a fall, cut, or arthritic knee). Neuropathic pain is treated by different medicines than pain from damaged tissue. Main results: Two studies tested gabapentin to treat fibromyalgia pain. One was identified in previous versions of the review and is included here. We identified another study as a It is not licensed for the treatment of fibromyalgia, but is commonly used because fibromyalgia can respond to the same medicines as neuropathic pain. Objectives: To assess the analgesic efficacy of gabapentin for fibromyalgia pain in adults and the adverse events associated with its use in clinical trials. To provide an overview of the therapeutic efficacy of pharmacological therapies for fibromyalgia (fibromyalgia syndrome) in adults, and to report on adverse events associated with their use. The major comparison of interest will be with placebo. News Release. Monday, June 11, 2007. Gabapentin Shown Effective for Fibromyalgia Pain. New research supported by the National Institutes of Health’s National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) shows that the anticonvulsant medication gabapentin, which is used for certain types of seizures, can be an effective treatment for the pain and other symptoms Gabapentin (original trade name Neurontin) is licensed for the treatment of peripheral and central neuropathic pain in adults in the UK at doses up to 3.6 grams (3600 mg) daily. It is given orally, as tablets or capsules. considered valuable by patients with chronic pain, showed that gabapentin was significantly better than placebo in postherpetic neuralgia (34% gabapentin versus 21% placebo; NNT 8.0, 95% CI 6.0 to 12) and painful diabetic neuropathy (38% versus 21%, NNT 5.9, 95% CI 4.6 to 8.3).
Articles and news, personal stories, interviews with experts.
Photos from events, contest for the best costume, videos from master classes.
![]() | ![]() |
![]() | ![]() |
![]() | |
![]() | ![]() |
![]() | ![]() |
![]() | ![]() |