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Gabapentin worked for me RLS wise, but took 3 weeks to kick in fully. The drug however gave me terrible moods swings, brain fog, and suicidal ideations, so I went off it. I was at 300mg 3x a day (to treat rls along with anxiety), when I first started that, I was also on ropinrole and my RLS symptoms (unless I was super stressed out) went away over time. I stopped taking the ropinrole, and now only use between 600-900mg gabapentin if my RLS symptoms flare. I have the worst RLS today (+ last night) I finally found my dogs gabapentin and took 800mg (google says 600mg is effective ), didn’t feel any better then took another 800mg. I still have some restlessness but now I’m super tired almost feel drunk. Pregabalin versus Gabapentin? Use this section to discuss your experiences with prescription drugs, iron injections, and other medical interventions that involve the introduction of a drug or medicine into the body. Gabapentin actually helps me sleep more than it helps the RLS. I need to take 1500-1800 mg, taking 3 600 mg doses 2 hours apart, for it to be effective for the RLS. I alternate between gabapentin, pramipexole, and kratom just to keep tolerances to a minimum. I am on Horizant (gabapentin enacarbil). It’s superior to plain old gabapentin because it metabolizes more slowly, therefore you only have to take 1 dose at night, less side effects, etc. Gabapentin is a good complement with your other RLS med. If regular gabapentin doesn’t work for you, ask your doc about changing to Horizant. You will need more and more to manage the restless legs because, oddly enough, it makes the condition much more severe. Then when you try to go off the drug, the rls is worse than anything you could imagine, plus you now have depression and anxiety and no motivation because your brain no longer knows how to make dopamine. I tried pregabalin but it did nothing for my RLS. Gabapentin helped but it kept having to be increased so I got off that. I don't know why anyone would be worried about taking Lyrica (pregabalin) it's simply a nerve med, usually used for diabetic nerve pain . Taking Ambien type sleeping pills is way more dangerous. The typical dose for RLS is 600 mg taken in the evening before symptoms start. However, gabapentin metabolizes quickly, and that’s not good for a solid night’s sleep. That’s why Horizant (gabapentin enacarbil) was made for RLS— it metabolizes much more slowly, so you are able to sleep through the night. If you find your symptoms rebounding in the night, Horizant is a good choice (Gabapentin enacarbil), it’s an extended release for RLS. Do keep in mind, many people with moderate to severe RLS need more than one class of meds to adequately treat symptoms. See our FAQ drug algorithm for more info. I just wanted to put a note here to say that I've suffered from restless legs for years slowly getting worse. I was on gabapentin for fibromyalgia for 5 yrs. I came off them earlier this year. my legs got 100 times worse so last night I took some left over gabapentin and I can't say how good my legs were through the night. I understand you are looking for alternative options to gabapentin for your restless legs. Do you know of the link between magnesium deficiency and restless legs? When was the last time you had your magnesium levels checked? Gabapentin has an average rating of 7.5 out of 10 from a total of 117 reviews for the off-label treatment of Restless Legs Syndrome. 68% of reviewers reported a positive experience, while 18% reported a negative experience. Here is how it happened for me: I started taking it for insomnia. I remember thinking “this pill doesn’t help me fall asleep, but it helps me stay asleep.” Then I started realizing my legs felt better, and I learned Gabapentin can be used to treat RLS. Gabapentin is effective for RLS. I would say Horizant (gabapentin enacarbil) is more effective. But many people with moderate RLS need more than one type of drug to bring symptoms under control. Old thread but I agree. I use to band dope for a long time, and yeah the RLS and cramps are the worst for me. Something about the RLS that multiplies my anxiety and restlessness by a factor of 10. I don't really get the vomiting and stuff, maybe cause I can never hold out that long haha. Beginning dose is usually 300 mg gabapentin. It will take 3 weeks before it is fully effective. After that increase it by 100 mg every couple of days until you find the dose that works for you. Take it 1 to 2 hours before bedtime as the peak plasma level is 2 hours. I felt no different except the RLS was starting to feel controlled. Then summer started, and I realized how much I was sweating, especially my face. My nose even sweats. And I live in Florida! So I gradually cut down to only 300 mgs. Rls is still pretty good, but when doc ordered a sleep study, found out I have apnea. Gabapentin is a very old med that has been used to treat all manner of neurological conditions over the years. I think of it as aspirin for the neurologist. It's two drawbacks are that dosing can be inconsistent due to issues with adsorption into the bloodstream. How long throughout the night and day do you feel the effects of gabapentin? I have restless legs throughout the day as well. I just went on gabapentin too and have found it helpful for like 12 hours after taking it at night but not helpful during the day. Congrats on the success so far!
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