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Hazard Description: Toxic. Contains a pharmaceutically active ingredient. Handling should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes. Statement of Hazard: Non-hazardous in accordance with international standards for workplace safety. Additional Hazard Information: Short Term: Dust may cause irritation (based on components) The active ingredient is not acutely toxic. Gabapentin is a medication commonly prescribed to treat various conditions, including epilepsy, neuropathic pain, and restless legs syndrome. This guide aims to educate patients about important considerations, including dosage instructions, potential side effects, and precautions, to ensure safe and effective use of gabapentin. Gabapentin is a nonprotein amino acid and a synthetic neurotransmitter that is related to γ-aminobutyric acid1 (GABA). It was first described in 1976 West German patent DE2460891 on cyclic amino acids to Gerhard Satzinger and co-inventors at Goedecke AG (Freiburg). The corresponding US Patent is 4,024,175 (1977). Gabapentin is a nonprotein amino acid and a synthetic neurotransmitter that is related to γ-aminobutyric acid1 (GABA). It was first described in 1976 West German patent DE2460891 on cyclic amino acids to Gerhard Satzinger and co-inventors at Goedecke AG (Freiburg). The corresponding US Patent is 4,024,175 (1977). Caution Statement: Each Gabapentin Tablets intended for oral administration contains Gabapentin and excipients generally considered to be non-toxic and non-hazardous in small quantities and under conditions of normal occupational exposure. Effects of Overexposure: Tablets are intended for human consumption under guidance of a physician. SAFETY CODE, CHAPTER 481, THESE SCHEDULES SUPERCEDE PREVIOUS SCHEDULES AND CONTAIN THE MOST CURRENT VERSION OF THE SCHEDULES OF ALL CONTROLLED SUBSTANCES FROM THE PREVIOUS SCHEDULES AND MODIFICATIONS. This annual publication of the Texas Schedules of Controlled Substances was signed by Jennifer A. Shuford, M.D., M.P.H., Commissioner of Health, and Water hazard class 2 (Self-assessment): hazardous for water Do not allow product to reach ground water, water course or sewage system. Danger to drinking water if even small quantities leak into the ground. Safety Data Sheet acc. to OSHA HCS Printing date 02/21/2024 Revision date 02/21/2024 Trade name:Gabapentin-d4 (Contd. from page 1) 58.0.12 · Hazard pictograms d~ GHS07 d~ GHS08 · Signal wordDanger · Hazard statements H315Causes skin irritation. H319Causes serious eye irritation. H360May damage fertility or the unborn child. H335May cause Neurontin; Ther. Class. analgesics. anticonvulsants. mood stabilizers. Pharm. Class. gamma aminobutyric acid gaba analogues. Controlled Substance Schedule: V(only schedule V in some states) There's more to see -- the rest of this topic is available only to subscribers. Material Name: Gabapentin Tablets (Neurontin) Trade Name: NEURONTIN; NORMATOL; GABAPENTIN Pfizer Chemical Family: Mixture Relevant Identified Uses of the Substance or Mixture and Uses Advised Against Intended Use: Pharmaceutical product used as anticonvulsant Details of the Supplier of the Safety Data Sheet 2. HAZARDS IDENTIFICATION Gabapentin -1.1 13. Disposal considerations Waste Disposal Methods Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. Chemical waste generators must also consult local, regional, and national hazardous waste regulations to ensure complete and accurate classification. Following concerns about abuse, gabapentin has been reclassified as a Class C controlled substance and is now a Schedule 3 drug, but is exempt from safe custody requirements. Healthcare professionals should evaluate patients carefully for a history of drug abuse before prescribing gabapentin, and observe patients for signs of abuse and dependence. Specific Target Organ Toxicity - Single Exposure 1 H370 Causes damage to the central nervous system and the visual organs. Aquatic Acute 3 H402 Harmful to aquatic life. Aquatic Chronic 3 H412 Harmful to aquatic life with long lasting effects. The product is classified and labeled according to the Globally Harmonized System (GHS). According to a classification scheme(2), this estimated Koc value suggests that gabapentin is expected to have high mobility in soil. Experimental pKa values for gabapentin are 3.68 (carboxylic acid) and 10.70 (primary amine)(4), indicating that this compound will primarily exist as a zwitterion in the environment. Chemical Book 7 Material Name: Gabapentin Capsules (100 mg, 300 mg and 400 mg) Trade Name: NEURONTIN; NEUGABA; GANTIN; PARKETIN; GABAPENTIN PFIZER Chemical Family: Mixture Relevant Identified Uses of the Substance or Mixture and Uses Advised Against Intended Use: Pharmaceutical product used as anticonvulsant Details of the Supplier of the Safety Data Sheet 2. SAFETY DATA SHEET According to JIS Z 7253:2019 Revision Number 2.03 Revision date 04-Feb-2023 Section 1: PRODUCT AND COMPANY IDENTIFICATION Product Name Gabapentin Product Code 076-05641,072-05643 Manufacturer FUJIFILM Wako Pure Chemical Corporation 1-2 Doshomachi 3-Chome Chuo-ku, Osaka 540-8605, Japan Phone: +81-6-6203-3741 NEURONTIN safely and effectively. See full prescribing information for NEURONTIN. NEURONTIN ® (gabapentin) capsules, for oral use NEURONTIN ® (gabapentin) tablets, for oral use NEURONTIN ® (gabapentin) oral solution Initial U.S. Approval: 1993 ----- Warnings and Pr ecautions, Respiratory Depression (5.7) 04/2020 Material Name: Gabapentin Tablets (Neurontin) Trade Name: Neurontin® Chemical Family: Mixture Intended Use: Pharmaceutical product used as anticonvulsant 2. HAZARDS IDENTIFICATION Appearance: White, eliptical, film-coated tablets Statement of Hazard: Non-hazardous in accordance with international standards for workplace safety. Additional Neurontin (gabapentin) is used to treat pain you may have from shingles (postherpetic nerve pain). It is also used with other seizure medicines for partial onset seizures in patients 3 years and older. Gralise (gabapentin) is only used for pain after having shingles (postherpetic nerve pain). It should not be used for any other medical condition.
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