In summary, the administration of gabapentin was effective in decreasing postoperative narcotic consumption and the incidence of pruritus. There was a high risk of selection bias and a higher heterogeneity of knee flexion range in this analysis. Overall, 17,970 patients (3% of all eligible patients) had a new prescription for gabapentin after surgery. Of these, the mean age was 73 years-old and 62% were female. The most common procedures were total knee (45%) and total hip (21%) replacements. Prolonged use occurred in 22%. Another type of medicine used as part of a multimodal pain regimen after hip replacement are medicines that target nerve pain – namely gabapentin (Neurontin) or pregabalin (Lyrica). Using these medications decreases the amount of opioids required after hip replacement. Some patients report that these medicines cause drowsiness, but they are Background: Pain management after total hip arthroplasty (THA) varies and has been widely studied in recent years. Gabapentin as a third-generation antiepileptic drug that selectively affects the nociceptive process has been used for pain relief after THA. This meta-analysis was conducted to examine the efficacy of gabapentin in THA. Pain management after total hip arthroplasty (THA) varies and has been widely studied in recent years. Gabapentin as a third-generation antiepileptic drug that selectively affects the nociceptive process has been used for pain relief after THA. This Gabapentin enacarbil is a prodrug with an extended-release formulation that has been proposed for multimodal postoperative analgesia, but the drug's efficacy for major arthroplasties remains unclear. Materials and methods: We enrolled 60 adult patients scheduled for primary knee or hip arthroplasty expected to remain hospitalized for at least 3 Gabapentin, a drug traditionally used for the relief of neuropathic pain, was compared in variable doses to placebo in relieving postoperative pain. Gabapentin resulted in less total patient-controlled analgesia (PCA) morphine use over 48 hours postoperatively ( P <0.05), better active knee flexion on postoperative days (PODs) 2 and 3 ( P <0.05 Epidural analgesia, femoral nerve block, lumbar plexus block and gabapentinoid administration are not recommended as the adverse effects outweigh the benefits. The following medical subject heading terms, keywords, and their combinations were used: “postoperative pain, total hip arthroplasty, total knee arthroplasty, total hip replacement, total knee replacement and gabapentin”. No restrictions were imposed on language or geographic location. Inclusion and exclusion criteria One study that demonstrated a favorable reduction in pain scores evaluated pregabalin for treatment of pain after total hip arthroplasty (THA) while the other study evaluated total knee arthroplasty (TKA) patients. Background Pain management after total hip arthroplasty (THA) varies and has been widely studied in recent years. Gabapentin as a third-generation antiepileptic drug that selectively affects the nociceptive process has been used for pain relief after THA. This meta-analysis was conducted to examine the efficacy of gabapentin in THA. Methods An electronic-based search was conducted using the The American Association of Hip and Knee Surgeons (AAHKS), The American Academy of Orthopaedic Surgeons (AAOS), The Hip Society, The Knee Society and The American Society of Regional Anesthesia and Pain Medicine (ASRA) have worked together to develop evidence-based guidelines on the use of gabapentinoids in primary total joint arthroplasty (TJA). Background Multimodal analgesia regimens are recommended for the postoperative period after hip and knee replacement surgeries. However, there are no data on practice patterns for analgesic use in the immediate postoperative period after hip and knee replacements in Australia. Objectives To describe analgesic prescribing patterns in the inpatient postoperative phase for patients undergoing hip Adding gabapentin to a multimodal regimen does not reduce acute pain, opioid consumption or chronic pain after total hip arthroplasty Acta Anaesth Scand. 2009; 53 :1073-1083 Crossref Another type of medicine used as part of a multimodal pain regimen after joint replacement are medicines that target nerve pain – namely gabapentin (Neurontin) or pregabalin (Lyrica). Using these medications decreases the amount of opioids required after joint replacement. Some patients report that these medicines cause drowsiness, but they Gabapentin is routinely used in preoperative multimodal anesthesia to reduce pain following total joint arthroplasty (TJA) surgery. Evolving evidence has shown it is ineffective in reducing postoperative pain and should be used cautiously in this patient population due to its adverse effects. All English-speaking patients aged 18 to 75 years scheduled for an eligible surgery (thoracotomy, video-assisted thoracoscopic surgery, primary or revision total hip replacement, primary or revision total knee replacement, unilateral or bilateral mastectomy, and breast lumpectomy with or without sentinel node biopsy or axillary node dissection Background Postoperative pain after total knee arthroplasty (TKA) and total hip arthroplasty (THA) influence patients’ rehabilitation and life quality. Although gabapentin has been widely used for analgesia, its efficacy is still controversial in TKA and THA. This meta-analysis was performed to assess the efficacy and safety of gabapentin following TKA and THA. Method Electronic databases By taking Gabapentin as prescribed, hip replacement patients can effectively manage their pain levels and enhance their overall comfort during the recovery process. This medication specifically targets nerve-related pain, making it an ideal choice for hip replacement patients who often experience nerve irritation and inflammation as part of US Pharm. 2011;36(11):Epub. Each year, hip fractures contribute to more than 225,000 hospitalizations in Medicare recipients, and this number is expected to double by the year 2040. 1 Length of stay for total hip arthroplasty (THA) has declined from 1991 to 2008, but this has resulted in an increase in post–acute care admissions and rehospitalizations. 2 According to the National Center for
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