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Nursing Considerations for Gabapentin. When administering or caring for patients taking gabapentin, nurses should consider several important factors. Nursing Assessment. 1. Assess the patient’s medical history, including any known allergies, previous adverse reactions to gabapentin or similar medications, and relevant medical conditions. Nursing actions: A. Assessment: 1 closely for notable changes in behavior that could indicate the emergence or worsening of suicidal thoughts or behavior or depression. 2: Assess location, duration, and characteristics of seizure activity. Understanding proper nursing considerations is crucial for safe and effective patient care. Generic name: Gabapentin. Brand names: Neurontin, Gralise, Horizant, Gabarone. Pharmacologic class: Anticonvulsant, Antiepileptic. Therapeutic class: Anticonvulsant, Analgesic for neuropathic pain. Read this chapter of Davis's Drug Guide for Rehabilitation Professionals online now, exclusively on F.A. Davis PT Collection. F.A. Davis PT Collection is a subscription-based resource from McGraw Hill that features trusted content from the best minds in PT. Find information on Gabapentin (Gralise, Horizant) in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF. Gabapentin is one of the top 100 drugs prescribed in the US, so there’s a very good chance it will show up on NCLEX or your nursing school exams. Let’s go through the key things you need to know about this medication using the Straight A Nursing DRRUGS framework. Gabapentin (Neurontin) interactions include: Increased risk of CNS depression when taken with CNS depressants, antihistamines, and alcohol. Decrease effect of gabapentin when taken with antacids, sevelamer, and cimetidine; so, space medication time 2 hours apart. So the action of Gabapentin is actually not known or understood. It is thought that Gabapentin may play a role in neural membranes. We use Gabapentin for the prevention of seizures for peripheral neuropathy, for neuropathic pain and for the prevention of migraines. Grab our free cheatsheet covering the 50 most commonly prescribed medications right here: to all the episodes at: Nursing Considerations Therapeutic Effects Side/Adverse Effects; Anticonvulsant: gabapentin: Administer first dose at bedtime to decrease dizziness and drowsiness Monitor for worsening depression, suicidal thoughts or behavior, and/or any unusual changes in mood or behavior Taper dose; do not stop abruptly: Decreased neuropathic pain or seizures Gabapentin in the management of restless legs syndrome (RLS) has been evaluated in small controlled trials, demonstrating benefits compared with placebo. Gabapentin enacarbil is FDA-approved for the treatment of RLS Garcia-Borreguero 2002, Saletu 2010. The . Social anxiety disorder, adjunct to antidepressants or monotherapy (alternative agent)c NCLEX Review: Gabapentin (Neurontin) - Mechanism of Action, Uses, Side effects, Contraindications, and Nursing considerationsAction: 0:20Uses: 0:29Side effec The precise mechanism through which gabapentin exerts its therapeutic effects is unclear. 16,17 The primary mode of action appears to be at the auxillary α2δ-1 subunit of voltage-gated calcium channels (though a low affinity for the α2δ-2 subunit has also been reported). 10,8,14 The major function of these subunits is to facilitate the Find information on Gabapentin (Gralise, Horizant) in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF. Mechanism of action: Gabapentin helps to stabilize cell membranes by changing cation (sodium, calcium, and potassium) transport, reducing excitability, and suppressing seizure focus or discharge. Indications for use: Adjunctive treatment for seizure control, postherpetic neuralgia, moderate to severe primary restless legs syndrome. SN to educate patient concerning the use of gabapentin is to increased pain relief affects by using the CNS to decrease symptoms of pain and assist Tramadol or other prescribed pain medications, even Tylenol ER in ultimate pain relief. Mechanism of action and indications (Why med ordered) -Gabapentin was designed to mimic the neurotransmitter GABA. It does not, however, bind to GABA receptors. Its mechanism of action as an antiepileptic agent likely involves its inhibition of the alpha 2-delta subunit of voltage-gated calcium channels. Advise patient not to take gabapentin within 2 hr of an antacid. Gabapentin may cause dizziness and drowsiness. Caution patient to avoid driving or activities requiring alertness until response to medication is known. Seizure patients should not resume driving until physician gives clearance based on control of seizure disorder. Nursing considerations Assessment. History: Hypersensitivity to gabapentin; lactation, pregnancy; Physical: Weight; T; skin color, lesions; orientation, affect, reflexes; P; R, adventitious sounds; bowel sounds, normal output; Interventions. Give drug with food to prevent GI upset. Arrange for consultation with support groups for people with Gabapentin is an anticonvulsive medication that received approval from the US Food and Drug Administration (FDA) in 1993 and has been available in generic form in the USA since 2004. Gabapentin was originally used as a muscle relaxant and an anti-spasmodic. However, it was later discovered that gabapentin has the potential of an anticonvulsive medication and can be used as an adjunct to more
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