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Taking gabapentin or pregabalin with opioids, anxiety meds or antidepressants, or if you have lung issues or are elderly, can lead to serious breathing problems. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. The most serious side effects of gabapentin in dogs include difficulty breathing, swelling of the face or tongue, hives, seizures, and collapse. If you notice any of these symptoms in your dog after taking gabapentin, contact your veterinarian immediately. Understanding the effects and potential side effects of gabapentin will allow you to make informed decisions and ensure the best possible care for your beloved feline companion. Watch this incredible video to explore the wonders of wildlife! More serious (but rare) side effects include suicidal thoughts or behavior, and mood changes in children. Combining gabapentin with certain medications, like opioids or benzodiazepines, can also lead to difficulty breathing and overdose in rare cases. If you experience any of these serious side effects, talk to your prescriber immediately. Learn more about how anticonvulsant drugs gabapentin and pregabalin can cause respiratory depression and what to do if you take these for chronic pain. In December 2019, the United States Food and Drug Administration (US FDA) issued a drug safety alert on serious breathing problems with gabapentin and pregabalin noticed when used along with central nervous system (CNS) depressants or in patients with lung problems. U.S. health regulators are warning that popular nervous system medications can cause dangerous breathing problems when combined with opioids and certain other drugs. The U.S. Food and Drug Administration (FDA) has release a warning related to the use of gabapentin and pregablin. Neurology > General Neurology FDA Warns of Breathing Problems With Gabapentinoids — Updated labeling for gabapentin, pregabalin, and new trials required. by Judy George, Senior Staff Writer On December 19, 2019 FDA is warning that serious breathing difficulties may occur in patients using gabapentin (brand names Neurontin, Gralise, Horizant) or pregabalin (brand names Lyrica, The primary concern is respiratory depression, which manifests as slow, shallow, and ineffective breathing. This can lead to a buildup of carbon dioxide in the blood and a decrease in oxygen levels, potentially causing serious health complications. FDA is requiring new warnings about the risk of serious breathing difficulties that can lead to death in Health care professionals and patients should report side effects from gabapentin, Check with your doctor immediately if any of the following side effects occur while taking gabapentin: More common in children. Some side effects of gabapentin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. The FDA reviewed multiple studies about the drugs’ effects on breathing. One study found that using pregabalin alone or with an opioid pain medicine could cause breathing problems. Another found that gabapentin alone caused longer pauses between breaths while people slept. Like all medicines, gabapentin can cause side effects, although not everyone gets them. Common side effects. These common side effects of gabapentin may happen in more than 1 in 100 people. They're usually mild and go away by themselves. There are things you can do to help cope with them: Feeling sleepy, tired or dizzy The agency is warning that serious breathing difficulties may occur in patients using gabapentin (Neurontin, Gralise, Horizant) or pregabalin (Lyrica, Lyrica CR) who have respiratory risk factors. Among those factors are use of opioid pain medicines and other drugs that depress the central nervous system (CNS), as well as conditions such as While gabapentin is widely prescribed for nerve pain, seizures, and other conditions, it carries a significant risk of respiratory depression, particularly in individuals with pre-existing respiratory conditions or when used in conjunction with other central nervous system depressants. Dangerous side effects could occur. Gabapentin side effects. Get emergency medical help if you have signs of an allergic reaction to gabapentin: hives, difficult breathing, swelling of your face, lips, tongue, or throat. Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Common side effects of gabapentin include: Feeling tired. Dizziness. Headache. Nausea and vomiting. Fever. Difficulty speaking. Recurring infections. Memory loss. Weight gain. Movement problems: coordination problems, being unsteady, tremors, jerky movements. Eye problems: unusual eye movements, double vision. Talk to your healthcare provider Gabapentin may cause slow and shallow breathing, especially if you have breathing problems from another condition or take other medicines that can slow your breathing. See the Interactions
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