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Common side effects from clinical trials included nausea, dizziness, headache, tiredness[2]. Has there been research into this treatment? Yes, although very few[3-6]. What does the research say? There is no evidence to show that gabapentin has a large positive effect in the treatment of tinnitus[2]. Tinnitus is a condition characterized by ringing or buzzing sounds in the ears. Gabapentin can reduce the severity of tinnitus symptoms and improve overall quality of life. Prevalence of tinnitus as a side effect of gabapentin ranges from 1% to 15%. Understanding Gabapentin and its Uses Controlled clinical trials investigating the effects of gabapentin on tinnitus have produced inconsistent results, with some studies suggesting a placebo effect and others indicating improvement with gabapentin use. However, these studies utilized a single drug dose and did not include objective measures of tinnitus loudness. My ears are still ringing loudly, and it is becoming very concerning. The neurologist said the gabapentin will not cause ear ringing. I called the drug mfgr. today and was told that it is a side effect (but not listed with their packet) and also that due to the long history of ear pain with the RHS it is not at all unusual. Gabapentin is more likely to cause tinnitus (ringing in the ears) than hearing loss – but both have been reported in users. A European Review by Altissimi et al. (2020) reported that gabapentin can induce “tinnitus” and “vertigo or dizziness” – but there was zero documentation of hearing loss & ototoxicity. Some medications can cause tinnitus, or ear ringing, as a rare side effect. Examples include aspirin, acetaminophen (Tylenol), and loop diuretics such as furosemide (Lasix). Tinnitus often resolves once you stop taking the medication. But don’t stop taking any medications without talking to your prescriber first. Ringing in Ears as a Potential Side Effect of Gabapentin. Many individuals who take gabapentin may experience ringing in their ears as a potential side effect of the medication. Ringing in the ears, also known as tinnitus, is a condition characterized by the perception of sound in the ears or head without an external source. Areas covered: This article review the evidence that long-term treatment with some antiepileptic drugs (AEDs) [e.g. carbamazepine, phenytoin, valproate, lamotrigine, gabapentin, vigabatrin and oxcarbazepine] (even in therapeutic drug doses) may result in tinnitus, phonophobia, sensorineural hearing loss, dizziness, ataxia, disequilibrium Side effects include tinnitus and sensorineural hearing loss (hearing loss due to nerve damage). Commonly used AEDs that are more likely to cause these side effects are: Depakote (valproate) Specific populations and risk factors for developing tinnitus as a side effect of gabapentin have been identified. Certain individuals may be more susceptible to this side effect, including those with pre-existing hearing disorders, a history of noise exposure, or a genetic predisposition. The VA even did a hearing test and only a Slight hearing loss at 8 Khz in only my right ear, and the ringing around 10 Khz. tinnitus a rare side effect of Most studies suggest that it isn't very effective. Tinnitus, or ringing in the ears, is a listed side effect of Neurontin (gabapentin). Interestingly enough, even though gabapentin can cause ringing in the ears, it is sometimes prescribed off-label for the treatment of it. Has anyone had severe tininitus caused by gabapentin? I have been on 1200mg/day of gabapentin for a couple of months now, and I have had a severe roaring in my ears for about a month. I also have pain. The most common gabapentin (Neurontin) side effects are dizziness and drowsiness. This may affect your ability to drive or perform other activities. Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common. For example, a 2011 controlled trial by Dehkordi et al. indicated that gabapentin had no positive effect on the treatment of tinnitus compared with placebo, although they reported that patients with hypertension, diabetes, and dyslipidemia all improved to a greater degree following treatment with gabapentin . There are 292,819 people reported to have side effects when taking Gabapentin. Among them, 1,338 (0.46%) have ringing in the ears. These people tend to be female, 50-59 old, have been taking the drug for < 1 month, also take medication Cymbalta, and have Depression Some side effects of gabapentin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Gabapentin is effective in reducing subjective and objective aspects of tinnitus in some individuals, with the best therapeutic response obtained in individuals with associated acoustic trauma. However, before considering gabapentin as a potential treatment, it is important to understand the potential side effects and risks associated with its use. Potential Side Effects and Risks of Gabapentin. Be aware, there are risks and potential side effects associated with the use of gabapentin for tinnitus treatment that should be considered Ringing in the ears (tinnitus): Persistent ringing or buzzing sounds in the ears can be a warning sign of potential hearing damage. Difficulty hearing: Struggling to hear conversations, especially in noisy environments, may signify auditory issues.
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