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Gabapentin and pregabalin are similar drugs but differ in several distinct ways. The main differences are their indications—specific uses that the Food and Drug Administration (FDA) has approved them to treat—and their dosages. If you’re looking for gabapentin alternatives, several prescription medications can help manage nerve pain, fibromyalgia, and anxiety. These include: Pregabalin: Doctors often prescribe pregabalin (Lyrica) as a substitute for gabapentin for nerve pain and fibromyalgia. A total of 270 drugs are known to interact with Gabapentin: 28 major drug interactions (148 brand and generic names) 232 moderate drug interactions (1026 brand and generic names) 10 minor drug interactions (52 brand and generic names) A total of 11 drugs are known to interact with Qutenza: 11 minor drug interactions (24 brand and generic names) Although a much safer alternative to opioids, there are still reasons to be cautious and careful in prescribing gabapentinoids. Both gabapentin and Lyrica can be used recreationally to produce a high. The risks of abuse are higher and of greatest concern in prior opioid users. 4 Lyrica is classified under federal law as a Schedule V drug. Gabapentin and Lyrica are similar drugs, but they do have some differences. For example, both drugs come as a capsule or liquid solution that you swallow. But gabapentin also comes as a tablet Are There Other Drugs That Can Be Taken Instead of Gabapentin? Pregabalin is Gabapentin alternatives for epilepsy, nerve pain, and anxiety. Other drugs for nerve pain include topiramate, baclofen, tricyclic antidepressants such as amitriptyline and Dosulepin, and serotonin-norepinephrine reuptake inhibitors such as duloxetine. 27 major drug interactions (146 brand and generic names) 341 moderate drug interactions (1371 brand and generic names) 1 minor drug interactions (2 brand and generic names) A total of 270 drugs are known to interact with Gabapentin: 28 major drug interactions (148 brand and generic names) 232 moderate drug interactions (1026 brand and generic If you are concerned about weight gain while taking gabapentin or a similar drug, it is important to talk to your doctor. They may be able to suggest dietary changes or exercise routines that can help minimize weight gain. It is important to note that abruptly stopping gabapentin or similar drugs can also lead to withdrawal symptoms. If gabapentin does not work for you, or if you believe the side effects are too severe, talk with your doctor to find an alternative medicine to treat nerve pain and/or seizures. Antidepressants Certain antidepressants work to relieve pain. Gabapentin is not the same as pregabalin, even though they both belong to the same class of medicine, called gabapentinoids, and work similarly. Lyrica and Lyrica CR are the only brands of pregabalin. Neurontin is a brand name for gabapentin. Other brands of gabapentin include Gralise and Horizant. While gabapentin (Neurontin) and pregabalin (Lyrica) share many similarities, there are a few things that set them apart. We’ll highlight seven key differences between these medications below. 1. Pregabalin is FDA approved for more uses than gabapentin, but both are often used off-label. 232 moderate drug interactions (1026 brand and generic names) 10 minor drug interactions (52 brand and generic names) A total of 270 drugs are known to interact with Neurontin: 28 major drug interactions (148 brand and generic names) 232 moderate drug interactions (1026 brand and generic names) 10 minor drug interactions (52 brand and generic Compare Gabapentin head-to-head with other drugs for uses, ratings, cost, side effects and interactions. The prescription-only drug pregabalin (Lyrica) is closely related to gabapentin. Children under the age of 65 should not take this medication. It is only appropriate for adults (under age 65). Gabapentin and Lyrica are both anticonvulsant medications used to treat seizures, post-herpetic neuralgia (pain from shingles), and certain other types of neuropathic pain. Both substances are classified as gabapentinoids—a group of drugs with similar mechanisms of (1) The first-line treatment for partial epilepsy is carbamazepine monotherapy; gabapentin monotherapy is an alternative, given its lower risk of drug-drug interactions. (2) The standard treatment for neuropathic pain associated with diabetes or post-herpetic neuralgia is a tricyclic antidepressant, with gabapentin as an alternative. Several natural substitutes for Gabapentin include capsaicin, turmeric, and ginger. Capsaicin cream is effective for localized pain relief, while turmeric contains curcumin, known for its anti-inflammatory properties. Taking gabapentin with other drugs that make you drowsy or slow your breathing can cause dangerous side effects or death. Ask your doctor before taking opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your current medicines. Many drugs can affect gabapentin, especially: naproxen;
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