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Gabapentin vs Hydroxyzine for Anxiety: Gabapentin for anxiety is sometimes prescribed off-label, offering a calming effect by modulating nerve activity. Hydroxyzine, an antihistamine, is also used for short-term anxiety relief, working quickly to induce sedation. Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is an antihistamine medication. [8] It is used in the treatment of itchiness, anxiety, insomnia, and nausea (including that due to motion sickness). [8] It is used either by mouth or injection into a muscle. [8] Hydroxyzine works by blocking the effects of histamine. [9] Although evidence is limited, some studies show gabapentin can help with anxiety symptoms. One 2020 review suggests gabapentin may help with different types of situational anxiety, Symptomatic relief of anxiety and tension associated with psychoneurosis; Parenteral: Adjunctive treatment in alcoholism; Allay associated anxiety and apprehension attendant to certain types of heart disease; Alleviating anxiety and tension in acute emotional problems or in the preparation for dental procedures Among the numerous options, two drugs stand out— hydroxyzine and gabapentin. Both medicines are considered viable options for treating sleep problems, particularly when combined with cognitive behavioral therapy for insomnia (CBT-i) coaching. Hydroxyzine may be used to relieve anxiety or itching; however, it causes sedation so can affect a person's ability to drive or operate machinery. It should not be used during pregnancy or while View more Neurontin (gabapentin) is primarily used to treat seizures and nerve pain but is also used with some frequency by psychiatrists to treat anxiety. Like hydroxyzine, gabapentin works quickly Hydroxyzine may be used to relieve itch or as a premedication before surgery to relieve anxiety. Experts are not sure exactly how hydroxyzine works in the brain but suggest it may suppress activity in certain key regions of the subcortical area of the central nervous system (which is the part of the brain located below the cerebral cortex). Gabapentin and pregabalin both have RCTs showing efficacy over placebo for social anxiety disorder; however, it should be noted that improvement was associated with higher doses than are often tolerated (e.g., >2,100 mg daily for gabapentin and 600 mg total daily for pregabalin) (113–115). Hydroxyzine is an antihistamine similar to over-the-counter (OTC) medications like Benadryl and Zyrtec that treat symptoms of allergies and colds. Unlike other antihistamines hydroxyzine has some unique characteristics that make it a great option for treating anxiety. Hydroxyzine is a drug prescribed to treat itching caused by a variety of allergic conditions, nausea, vomiting, and alcohol withdrawal. Common side effects of hydroxyzine are sedation, tiredness, sleepiness, dizziness, disturbed coordination, drying and thickening of oral and other respiratory secretions, and stomach distress. Do not take hydroxyzine if pregnant or breastfeeding. tell your doctor if you are breastfeeding. Do not breastfeed while taking hydroxyzine. talk to your doctor about the risks and benefits of taking hydroxyzine if you are 65 years of age or older. Older adults should not usually take hydroxyzine because it is not as safe as other medications that can be used to treat the same condition. There are currently no known ongoing trials of gabapentin for anxiety disorders. Another anticonvulsant, tiagabine, is FDA-approved for the treatment of partial seizures and has been shown to have potential anxiolytic effects in preclinical studies . Applies to hydroxyzine: compounding powder, intramuscular solution, oral capsule, oral suspension, oral syrup, oral tablet. General adverse events The most commonly reported side effects included sleepiness, headache, and tiredness. Hydroxyzine is used to help control anxiety and tension caused by nervous and emotional conditions. It can also be used to help control anxiety and produce sleep before surgery. This medicine is also used to relieve symptoms of allergic conditions (eg, chronic urticaria and atopic and contact dermatoses). Hydroxyzine is an antihistamine. Hydroxyzine is also used to treat allergic skin reactions such as hives or contact dermatitis. Warnings. Hydroxyzine may cause birth defects. Talk to you doctor before using hydroxyzine if pregnant or breastfeeding. Hydroxyzine can cause a serious heart problem, especially if you use certain medicines at the same time. My Doc recently prescribed me gabapentin to take with my hydroxyzine for my panick attacks. My anxiety is so bad though that I'm scared of trying it cause I don't like feeling "loopy" and it makes me panic more. Find patient medical information for hydroxyzine HCl oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Many members combine gabapentin or hydroxyzine pamoate with other treatments to manage generalized anxiety disorder in adults. Sertraline Hydrochloride is more frequently combined with gabapentin, while Escitalopram Oxalate is slightly more popular among hydroxyzine pamoate users. Hydroxyzine, known as Vistaril, is often highlighted for its use in anxiety management. This piece explores how hydroxyzine stacks up against other common anxiety drugs, like Xanax (alprazolam). It focuses on what makes them different in terms of benefits and side effects.
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