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Lyrica is a brand name for pregabalin, while gabapentin is a generic name for a similar drug. Learn about the main differences, side effects, and interactions of these anti-epileptic and nerve pain medications. Gabapentin is contraindicated in individuals who have hypersensitivity to this medication or its components, which can cause fever and other symptoms that could become severe. Pregabalin vs Gabapentin â What is the Difference? Pregabalin and gabapentin can both provide relief from pain and be effective ways to manage seizure disorders. Continue reading for an in-depth comparison of pregabalin versus gabapentin, including an analysis of their respective uses, proven efficacy, dosing regimens, side effects, and more. One of the primary differences between gabapentin and pregabalin is that the FDA has approved both drugs for some of the same indications but also different ones. Gabapentin Vs Pregabalin Side Effects. The side effects of both Gabapentin and Pregabalin are similar; however, some studies indicate that Pregabalin may have a lower risk of adverse effects. Two of the most common side effects of Gabapentin and Pregabalin include sleepiness and dizziness. Both medications have common side effects, such as drowsiness, dizziness, and edema. But pregabalin is more likely to cause weight gain. More serious side effects, such as suicidal thoughts and behaviors, heart problems, or misuse, are more rare. One of the side effects of gabapentin is that it can cause mental confusion and forgetfulness. I have not heard that it can cause dementia but the side effects could be misdiagnosed as dementia. Jump to this post Common side effects include dizziness, drowsiness, and fatigue. How Do Pregabalin and Gabapentin Work? Pregabalin and Gabapentin work by affecting nerve signals in the brain to reduce pain and prevent seizures. Both medications target calcium channels in nerve cells, slowing down excessive nerve activity. In addition to the mild side effects described above, serious side effects may occur in some people taking Lyrica or gabapentin. See the table below for a list of side effects that have been Pregabalin (Lyrica) and gabapentin (Neurontin and others) are drugs used to prevent seizures and to treat nerve pain associated with various conditions (shingles, diabetic neuropathy). Lyrica and gabapentin both cause similar side effects, including tremors, blurred or double vision, memory or concentration problems, dizziness, and drowsiness. Pregabalin starts working faster because it is absorbed more quickly than gabapentin. The common side effects of Pregabalin include dry mouth, blurred vision, headache, weight gain, indigestion, and constipation. At the same time, the common side effects of Gabapentin include – shaking, diarrhea, dizziness, drowsiness, and weakness. Compare Gabapentin vs Lyrica head-to-head with other drugs for uses, ratings, cost, side effects and interactions. This is because both Lyrica and gabapentin can increase the risk of serious side effects if you suddenly stop taking them. The side effects include seizures and withdrawal symptoms, The study showed that treatment with gabapentin resulted in more pain relief and had less risk of side effects when compared to pregabalin. But keep in mind that neither gabapentin nor pregabalin are recommended as first-choice sciatica medications. In addition, Lyrica was initially thought to have less side effects than gabapentin since the drugs are so similar to one another but Lyrica is dosed in far less amounts. However, this doesn't appear to be the case and the side effects experienced from the drugs will vary by the individual. Learn how gabapentin and pregabalin differ in their absorption, bioavailability, metabolism, and binding to calcium channels. Compare their indications, dosing, and common side effects such as confusion, peripheral edema, and withdrawal symptoms. Gabapentin is an anticonvulsant with pain-relieving effects that may be used to treat certain seizure disorders or relieve nerve pain. Common side effects include dizziness or drowsiness and it may more. Pregabalin is used in the treatment of nerve pain and also to prevent seizures. Gabapentin is more likely to cause different side effects from pregabalin, including: Fever; Increased risk of infection; Difficulty speaking; Jerky movements; Unusual eye movements Side Effects: Lyrica vs Gabapentin Though the side effect profiles of both drugs are similar, some studies have found that Lyrica may have somewhat fewer of them. Dizziness and sleepiness are the most common side effects associated with both drugs, but more serious concerns such as suicidal ideation have also been reported. 1 That said, differences in the occurrence rates of side effects for pregabalin and gabapentin may be less significant than available medical literature suggests. As of current, there are no convincing data to substantiate the idea that pregabalin is significantly more tolerable (i.e. causes fewer side effects) than gabapentin – or vice-versa. Gabapentin (Neurontin) and pregabalin (Lyrica) are both antiepileptic medications used to treat nerve pain and seizures, but they have some differences. Gabapentin is available as a lower-cost generic and is typically taken three times a day, while pregabalin is also available as a generic but is usually taken two or three times a day.
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