Gabapentin (kemiskt namn 1-(aminometyl)cyklohexanättiksyra [1]) är ett antiepileptikum som används vid epilepsi och smärtsam diabetesneuropati. Det är en GABA -analog; däremot agerar den inte på GABA-receptor utan inhiberar specifika kalciumkanaler. Gabapentin besitzt dabei eine Halbwertszeit von 5 bis 7 Stunden im Blut, ausgeschieden wird es über den Harn. [17] Während Gabapentin beim Menschen unverändert ausgeschieden wird, erfolgt beim Hund eine Verstoffwechslung zu N-Methyl-Gabapentin, weshalb bei Hunden eine schnellere Elimination und damit kürzere Wirksamkeit zu verzeichnen ist. [18] Common Trade Names: Neurontin, Gralise; Adult Dosing Partial Seizures. Adjunctive therapy for partial seizures with or without secondary generalization; Initial: 300mg PO q8hr; May increase up to 600mg PO q8hr; Post herpetic neuralgia. Day 1: 300mg PO qDay; Day 2: 300mg PO q12hr; Day 3: 300mg PO q8hr; Muscle Cramps (Off-label) Gabapentin is an anticonvulsive medication that received approval from the US Food and Drug Administration (FDA) in 1993 and has been available in generic form in the USA since 2004. Gabapentin was originally used as a muscle relaxant and an anti-spasmodic. Gabapentin is in a class of medications called anticonvulsants. Gabapentin treats seizures by decreasing abnormal excitement in the brain. Gabapentin relieves the pain of PHN by changing the way the body senses pain. It is not known exactly how gabapentin works to treat restless legs syndrome. Gabapentin is used to treat epilepsy. It's also taken for nerve pain, which can be caused by different conditions, including diabetes and shingles . Nerve pain can also happen after an injury. Gabapentin enacarbil (Horizant (ER) (U.S. Tooltip United States), Regnite (in Japan)) is an anticonvulsant and analgesic drug of the gabapentinoid class, and a prodrug to gabapentin. [1] It was designed for increased oral bioavailability over gabapentin, [ 2 ] [ 3 ] and human trials showed it to produce extended release of gabapentin with Il gabapentin [2] è il nome del principio attivo indicato specificamente nel dolore post-erpetico e nell'epilessia parziale resistente alle terapie standard. È un farmaco analgesico e anticonvulsivante . Gabapentina é um fármaco da classe dos anticonvulsivantes, análogo de GABA.Foi desenvolvido para o tratamento da epilepsia e acabou também por passar a ser utilizado para o tratamento de dor ocasionadas pelos nervos periféricos. Gabapentinoids are a class of drugs that bind to the α 2 δ protein of voltage-gated calcium channels and reduce the release of excitatory neurotransmitters. They are used for various medical conditions, such as epilepsy, neuropathic pain, fibromyalgia, and anxiety, but have some side effects and off-label uses. Gabapentin is a drug used to treat neuropathic pain and partial seizures of epilepsy. It acts by binding to a protein that regulates calcium channels in the nervous system. Learn about its history, uses, side effects, and controversies. Gabapentin is commonly used to treat and prevent seizures in people with epilepsy or to treat nerve pain (postherpetic neuralgia) that can occur after a viral infection called shingles. Gabapentin, yang dijual di bawah jenama Neurontin, ialah ubat anti-kejang yang digunakan untuk dalam rawatan sawan separa, sakit neuropatik, kilat panas dan sindrom kaki resah. [ 4 ] [ 5 ] Ia adalah antara ubatan yang disyorkan sebagai sebahagian daripada rawatan permulaan bagi rawaran neuropati diabetik, neuralgia postherpetik dan sakit Gabapentin is a prescription medication that mimics the effects of GABA, a brain chemical that reduces nerve excitability. It is used to treat seizures, nerve pain and restless legs syndrome. Learn how to take gabapentin, what side effects to watch for and what drugs to avoid. Gabapentín, pod zaščitenim imenom Neurontin in drugimi, je strukturni analog GABA z protiepileptičnim učinkom, vendar ni gabamimetik, 가바펜틴(Gabapentin)는(상품명으로 '뉴론틴' 등이 사용된다) 1973년 미국 화이자사가 개발하여, 뇌전증 및 신경성 통증에 사용되어, 약물과의 상호 작용이 적은 삶의 질을 높이는 항경련제이다. Gabapentin is a medicine used to treat seizures, nerve pain and restless leg syndrome. It belongs to a group of medicines called anticonvulsants and has different brand names and forms. Learn about its warnings, interactions and how to take it safely. Gabapentin is an anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures. La gabapentine, molécule chimique dérivé de l'acide γ-aminobutyrique, est un médicament commercialisé sous le nom commercial de Neurontin ou génériques.. Il est utilisé en médecine humaine comme antiépileptique, antalgique, co-analgésique et étudié comme anxiolytique en prescription hors AMM (). A gabapentin epilepszia, nyugtalan láb szindróma (en) és neuropátiás fájdalom (en) elleni hatóanyag. Használják mellrák-kezelés vagy menopauza okozta bőrpír és izzadás ( hőhullám (en) ) ellen is.
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