I've tried both gabapentin and pregabalin. I found the Lyrica brand better than generic even though they say is same active ingredient. Anyway, Lyrica gives me a sense of happiness as well as pain killer for post herpetic neuralgia. The neurontin nor generic gabapentin didn't make me feel relaxed like the Lyrica does. And yes, weight gain. Pregabalin (Lyrica) and gabapentin (Neurontin and others) are drugs used to prevent seizures and to treat nerve pain associated with various conditions (shingles, diabetic neuropathy). Lyrica and gabapentin both cause similar side effects, including tremors, blurred or double vision, memory or concentration problems, dizziness, and drowsiness. For this study, a key measure was whether a medication reduced discomfort by 50%. The most effective treatment was nortriptyline. Of the study subjects taking this medication, 25% reported their discomfort improved by at least 50%. The least effective treatment was pregabalin: only 15% of study subjects reported that much improvement. However, pregabalin may either have an additional system of absorption or be better transported than gabapentin, as it is almost completely absorbed, while gabapentin is not. In addition, absorption of gabapentin is limited to the small intestine, while pregabalin is absorbed throughout the small intestine and extending to the ascending colon. If directly comparing the cost of “brand name” Lyrica capsules to the cost of “brand name” Neurontin capsules/tablets, it seems as though brand name Lyrica is (1) more expensive than brand name Neurontin among low-dose users; and (2) less expensive than brand name Neurontin among high-dose users. It is known that 50 mg Lyrica is Thirty-eight patients (25.2%) in the gabapentin group achieved therapeutic dose compared with 120 patients (79.5%) receiving pregabalin (P <.001). The median time to therapeutic dose for patients Pregabalin resulted in lower opioid consumption (OR 0.50, 95% CI 0.33–0.76). Gabapentin had a higher incidence of nausea and vomiting. Sensitivity analysis supported the efficacy of pregabalin. Conclusion. In conclusion, pregabalin demonstrated superior and faster efficacy in alleviating neuropathic pain than gabapentin did. When you're comparing gabapentin versus Lyrica, you should consider the benefits and risks. Gabapentin is used to treat partial seizures that occur with epilepsy and nerve pain resulting from In a research study comparing the potential for addiction, neither gabapentin nor pregabalin were found to be particularly addictive. However, the researchers concluded that pregabalin seemed “somewhat more addictive” than gabapentin due to the greater extent of behavioral changes that may indicate dependence on pregabalin use. However, a review of studies found Lyrica to be more effective than gabapentin for treating nerve pain that occurs after shingles. Although pregabalin and gabapentin share similarities in their mechanisms of action, they exhibit some pharmacokinetic and pharmacodynamic differences. In terms of pharmacokinetics, pregabalin demonstrates higher oral bioavailability, faster absorption, and a more predictable dose-response relationship than gabapentin (6, 7). Pregabalin (Lyrica) and gabapentin (Neurontin) are both approved to treat nerve pain. How are they different, and which one is preferred? Compare both meds here. I now advocate for deprescribing gabapentin when patients do not achieve adequate pain relief for chronic neuropathic pain at a cumulative daily dose of 1800 mg. Instead, I consider pregabalin as a substitute for gabapentin in patients with inadequate pain control rather than further dose escalations. Both Lyrica and gabapentin are used as anti-epileptic medications and to treat nerve pain. But there are several differences between them. The main differences between Lyrica and gabapentin are: Lyrica is a brand name for pregabalin. Gabapentin is a generic name - brands of gabapentin include Neurontin, Gralise, and Horizant. In terms of efficacy, one study showed that Lyrica was 2.4 times more potent than Gabapentin for epilepsy, which likely means it could be considered more potent for neuropathic pain. Hi @maria7521-- that's a good question.I took gabapentin for about 2 weeks before I talked with the doctor and found out after question them that it is only used to address the pain from neuropathy and I only have numbness which is does nothing for so I stopped taking it. Gabapentin is an anticonvulsant with pain-relieving effects that may be used to treat certain seizure disorders or relieve nerve pain. Common side effects include dizziness or drowsiness and it may more. Lyrica can help relieve nerve pain and control seizures but it is likely to cause drowsiness. 2025 Copyright | All Rights Reserved. Privacy Policy lyricaegj.com Lyrica and gabapentin are two prescription drugs used to treat nerve pain and focal onset seizures. Find out how they’re alike and different.
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