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The images above are shown for illustration purposes only. They may not be an exact representation of the product. This medication requires a prescription. The formulas and/or statements listed are provided for educational purposes only. These custom-blended agents use a concoction of commonly used drugs. Compounded pain creams differ when used for neuropathic pain (ketamine, gabapentin, clonidine, and lidocaine), nociceptive pain (ketoprofen, baclofen, cyclobenzaprine, and lidocaine), or mixed pain (ketamine, gabapentin, diclofenac, baclofen, cyclobenzaprine, and lidocaine). Compounded pain creams differ when used for neuropathic pain (ketamine, gabapentin, clonidine, and lidocaine), nociceptive pain (ketoprofen, baclofen, cyclobenzaprine, and lidocaine), or mixed A new topical cream with gabapentin 6 percent, ketoprofen 10 percent, lidocaine 5 percent, and ketamine 10 percent was prescribed in addition to an oral mucosal topical agent containing gabapentin 10 percent in Orabase. What is Baclofen 2%/Ketoprofen 10%/Lidocaine 5%/Gabapentin 5% Topical Cream? This is a compounded formulation of four active ingredients: Baclofen, Ketoprofen, Lidocaine, and Gabapentin. It is a semisolid preparation designed for convenient and controlled application on the skin for localized treatment or absorption of these active ingredients. Gabapentin 4-10% AMPA-Na Channel Blocker Lidocaine 2-5% AMPA-Na Channel Blocker Diclofenac 2-10% Anti-inflammatory Ibuprofen 10-20% Anti-inflammatory Ketoprofen 5-20% Anti-inflammatory Naproxen 10-20% Anti-inflammatory Piroxicam 2-4% Anti-inflammatory The Gabapentin 10%/Ketoprofen 15%/Lidocaine HCl 5%/Menthol 5% Topical Cream is a specially compounded semisolid preparation intended for localized treatment of neuropathic pain, inflammatory conditions, and associated symptoms. Mixed pain: The active treatment was 10% ketamine, 6% gabapentin, 3% diclofenac, 2% baclofen, 2% cyclobenzaprine, and 2% lidocaine. Creams were compounded in a typical pharmacy compounding base (carrier). Gabapentin 1%, 5%, 10% Cream or Gel. Gabapentin topical creams and gels have been shown to be effective for treating chronic neuropathic pain. Neuropathic pain is pain coming from damaged nerves. It differs from pain messages carried along healthy nerves from damaged tissue that can come from a burn or a cut. Intervention: Pain creams compounded for neuropathic pain (ketamine, gabapentin, clonidine, and lidocaine), nociceptive pain (ketoprofen, baclofen, cyclobenzaprine, and lidocaine), or mixed pain (ketamine, gabapentin, diclofenac, baclofen, cyclobenzaprine, and lidocaine), or placebo. Ketoprofen - This is a non-steroidal anti-inflammatory drug (NSAID) that works to reduce inflammation and pain. Ketoprofen is similar to ibuprofen and naproxen but is more effective topically than either of those agents. An advantage of topical ketoprofen is that high tissue concentrations are achieved without high systemic concentrations. A variety of gel and cream bases have been used to make topical “Triple Cream” products and for this reason the base may differ depending on which compounding pharmacy and recipe is used. The researchers think there was a tiny difference favoring the pain creams because they contained two substances—lidocaine and prescription non-steroidal anti-inflammatory drugs, particularly ketoprofen and diclofenac—that were shown in earlier randomized trials to be effective topically. Gabapentin (Neurontin, cyclohexaneacetic acid, C 9 H 17 NO 2, MW 171.24) occurs as a white to off-white, crystalline solid that is freely soluble in water and in alkaline and acidic solutions. A 2% aqueous solution has a pH of 6.5 to 8.0. Gabapentin is an anticonvulsant that is structurally related to gamma-aminobutyric acid. Gabapentin/Ketoprofen/Lidocaine Transdermal Gel is a compounded medication that combines three active ingredients, Gabapentin, Ketoprofen, and Lidocaine, at specific concentrations to manage pain, inflammation, and nerve-related issues locally through application on the skin. This cream combines the actions of gabapentin, an anticonvulsant that is also used to relieve neuropathic pain; ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain; and lidocaine, a local anesthetic that numbs the treated area. This compounded formulation of Baclofen 2%/Ketoprofen 10%/Lidocaine 5%/Gabapentin 5% Topical Cream is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin for localized treatment or absorption of active ingredients. It is a compound medication, containing Ketoprofen, Gabapentin, and Lidocaine. Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) that treats inflammation and provides analgesia; Gabapentin is an antiepileptic medication used to control seizures and treat neuropathic pain; and Lidocaine is a local anesthetic that blocks pain nerve I’ve been pleasantly surprised to find that Ketamine/Lidocaine and DMSO creams help with my widespread body pain a great deal. I suffer from fibromyalgia, but I originally got the creams for severe hernia pain, which they also help with. The K cream for me is at 10%, and the Lido is at 5%. Gabapentin taken orally has been used for treatment of partial seizures,55 postherpetic neuralgia,56 migraine headaches,57 and other pain syndromes.58,59 Fortunately, gabapentin has a low profile of adverse effects and few interactions with other medi-cations because it requires high doses to achieve neuropathic pain relief.
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