CONCLUSIONS: Hypoglycemia is a rarely acknowledged adverse effect of gabapentin overdose and requires urgent intervention as it could be initially resistant to simple glucose replacement and may lead to serious consequences. In this case, blood glucose levels responded only to high concentration dextrose infusion (D10) with concomitant tube feeds. She received 4200 mg of gabapentin weekly for neuropathic pain, where 900 mg weekly was recommended for patients undergoing haemodialysis. Nadir blood glucose was 1.9 mmol l −1 which was corrected with dextrose. Objective: A possible case of gabapentin-induced mild hyperglycemia is reported. Case Summary: A 63-year-old Caucasian gentleman was treated in a pharmacist-run pharmacotherapy clinic for type 2 Began some medical journal research and found an obscure paper indicating that, in rare instances, gabapentin may cause lowering of blood sugar. Since then my oral blood sugar medication requirements have dropped significantly. The study uses data from the FDA. It is based on gabapentin (the active ingredients of Gabapentin) and Gabapentin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. During hypoglycaemia, symptoms like palpitations, tremor, hunger, sweating and neuroglycopenic symptoms are accompanied by measured plasma glucose concentration below 3.9 mmol/l (70 mg/dl). In the case of severe hypoglycaemia, the event requires assistance of another person to administer carbohydrates, glucagon or resuscitative actions [2]. 2 Answers - Posted in: gabapentin, blood disorders - Answer: My wife is type 2 diabetic and takes gabapentin for years and it does not Gabapentin is FDA-approved as Neurontin to treat partial seizures in adults and children with epilepsy. Partial seizures are convulsions that originate from a single location in the brain. Neurontin is also approved to treat a type of nerve pain called postherpetic neuralgia, or PHN. gabapentin, dosage, blood disorders. Further information. Gabapentin uses and safety info; Gabapentin prescribing info & package insert (for Health Professionals) Side effects of Gabapentin (detailed) Similar questions Despite adequate pain control achievement following gabapentin initiation, blood glucose values continued to rise. From a search of the medical literature, 2 articles speak to the effect of gabapentin on blood glucose levels. The short answer is: yes, it is possible, though not very common, for gabapentin to raise your blood sugar. Studies have shown that approximately 1.2% of patients treated with gabapentin may experience hyperglycemia (high blood sugar) compared to 0.4% with a placebo. If you have diabetes or high blood sugar, you probably know some of the things that cause your glucose (another name for blood sugar) to go up. Like a meal with too many carbohydrates, or not Gabapentin appears to have effects on several voltage-gated calcium channels. Hypoglycemia may be due to gabapentin binding to the alpha 2 delta subunit of the calcium channels in the pancreas. Future research should investigate gabapentin and the potential for hypoglycemia. Gabapentin, a medication commonly used for neuropathic pain, has been associated with varying effects on blood sugar levels. This article synthesizes findings from multiple case reports to provide a comprehensive understanding of how gabapentin may influence blood glucose, highlighting both hypoglycemia and hyperglycemia. The most common gabapentin (Neurontin) side effects are dizziness and drowsiness. This may affect your ability to drive or perform other activities. Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common. Rare but serious gabapentin side effects include mood changes in children. Steroids — either as pills or injection — can raise blood sugar levels while you’re taking them (this is much less likely with inhaled steroids). This can be a problem in people who already have diabetes and in people who don’t have diabetes. Increased blood sugar is more likely if you take higher doses of steroids over the long term.
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