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Ask your doctor before using acetaminophen together with ethanol (alcohol). This can cause serious side effects that affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or the whites of your eyes. Caution should be taken when using OTC medications that would increase the drowsiness side effect of gabapentin. This effect can occur when combining gabapentin and Benadryl (diphenhydramine) or gabapentin and Unisom (doxylamine). Some common combinations of gabapentin and OTC medications for allergy relief and pain relief include: Side effects of diphenhydramine include symptoms of CNS depression including drowsiness, confusion, dizziness, and dry mouth. Below, we discuss whether or not Benadryl interacts with the medications in question. Taking Benadryl With Gabapentin. Gabapentin is used for a wide variety of indications such as neuropathy and epilepsy. The following applies to the ingredients: Diphenhydramine (found in Benadryl) and Gabapentin MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients. Drug Interactions between Benadryl and gabapentin. This report displays the potential drug interactions for the following 2 drugs: Benadryl (diphenhydramine) gabapentin; Edit list (add/remove drugs) Consumer; Professional; Interactions between your drugs Other trazodone interactions can occur with Benadryl (diphenhydramine), buspirone (Buspar), and gabapentin (Neurontin). Trazodone can also interact with medications that increase serotonin levels such as Lexapro (escitalopram), Prozac (fluoxetine), and Cymbalta (duloxetine). It can also interact with medications that may cause bleeding such as When that happens, it's called a drug interaction. It could make your medication stop working, become less effective, or too strong. It could also trigger side effects. The more you learn about Using diphenhydrAMINE together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. 446 medications are known to interact with diphenhydramine. Includes amlodipine, gabapentin, lisinopril. Applies to: Benadryl (diphenhydramine) and Neurontin (gabapentin) Using diphenhydrAMINE together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. The combination of gabapentin and Benadryl (diphenhydramine) is a common concern for individuals managing pain, seizures, or sleep disturbances. While both medications are widely used, their interaction can lead to enhanced side effects, potentially posing significant risks. Drug interactions are reported among people who take Gabapentin (gabapentin) and Benadryl (diphenhydramine hydrochloride). Common drug interactions include pyrexia among females and fatigue among males. If you are taking both Benadryl and Gabapentin, it is important to understand the potential interactions between these medications. Benadryl, an antihistamine, and Gabapentin, an anticonvulsant, can have additive effects on the central nervous system. Using diphenhydrAMINE together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. Drug Interactions: A total of 446 drugs are known to interact with Diphenhydramine: 14 major drug interactions (90 brand and generic names) 430 moderate drug interactions (1668 brand and generic names) 2 minor drug interactions (8 brand and generic names) A total of 270 drugs are known to interact with Gabapentin: Review detailed drug interaction details between Diphenhydramine and Gabapentin, including severity, interaction details, how to manage the interaction, and more. Phenobarbital. In comparison to cimetidine, phenobarbital presents the opposite problem when it comes to drug interactions. A commonly prescribed anti-seizure medication, phenobarbital makes the body produce more CYP enzymes, which increases the clearance and decreases the effectiveness of many types of medications, including digoxin, glucocorticoids, amitriptyline, clomipramine, theophylline A phase IV clinical study of FDA data: drug interactions are found among 2,435 people who take Gabapentin (gabapentin) and Diphenhydramine hydrochloride (diphenhydramine hydrochloride). There is no known drug interaction between Benadryl and medications prescribed for high blood pressure. However, Benadryl can increase the side effects of metoprolol succinate (Toprol XL) and metoprolol tartrate (Lopressor), which can lead to low blood pressure, dizziness, and slow heart rate.
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