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Rarely, more severe side effects of gabapentin and pregabalin may include: Suicidal thoughts or behaviors Respiratory depression (slow, shallow breathing), especially if taken with other drugs or substances that are central nervous system (CNS) depressants, such as alcohol Pregabalin (Lyrica) and gabapentin (Neurontin and others) are drugs used to prevent seizures and to treat nerve pain associated with various conditions (shingles, diabetic neuropathy). Lyrica and gabapentin both cause similar side effects, including tremors, blurred or double vision, memory or concentration problems, dizziness, and drowsiness. In addition to the mild side effects described above, serious side effects may occur in some people taking Lyrica or gabapentin. See the table below for a list of side effects that have been Side Effects: Pregabalin vs Gabapentin Comparison of Common Side Effects. The most common side effects of Lyrica include dizziness, drowsiness, headache, dry mouth, blurred vision, constipation, peripheral edema (swelling in the limbs), weight gain, and indigestion. Side effects of Lyrica vs. gabapentin. Both Lyrica and gabapentin treat partial onset seizures and nerve pain that occurs after shingles. These drugs can cause some of the same side effects, as Gabapentin (Neurontin) and pregabalin (Lyrica) are both antiepileptic medications used to treat nerve pain and seizures, but they have some differences. Gabapentin is available as a lower-cost generic and is typically taken three times a day, while pregabalin is also available as a generic but is usually taken two or three times a day. Side effects are generally similar for pregabalin and gabapentin. But there are a few differences to be aware of. Common side effects. Dizziness and drowsiness are the most common side effects of pregabalin and gabapentin. It may be less of an issue with Gralise and pregabalin ER. Other possible side effects include: Side Effects: Lyrica vs Gabapentin. Though the side effect profiles of both drugs are similar, some studies have found that Lyrica may have somewhat fewer of them. Dizziness and sleepiness are the most common side effects associated with both drugs, but more serious concerns such as suicidal ideation have also been reported. 1 2025 Copyright | All Rights Reserved. Privacy Policy lyricaegj.com That said, differences in the occurrence rates of side effects for pregabalin and gabapentin may be less significant than available medical literature suggests. As of current, there are no convincing data to substantiate the idea that pregabalin is significantly more tolerable (i.e. causes fewer side effects) than gabapentin – or vice-versa. Dizziness and somnolence are the most common side effects in both drugs (>20% seen in gabapentin). 3-5 Confusion and peripheral edema have also been reported with gabapentin. 4. With both drugs, side effects are dose dependent and reversible if the medication is discontinued. 3 The abrupt discontinuation of any form of gabapentin is not Gabapentin is an anticonvulsant with pain-relieving effects that may be used to treat certain seizure disorders or relieve nerve pain. Common side effects include dizziness or drowsiness and it may View more. Prescription only. Lyrica can help relieve nerve pain and control seizures but it is likely to cause drowsiness. In addition, Lyrica was initially thought to have less side effects than gabapentin since the drugs are so similar to one another but Lyrica is dosed in far less amounts. However, this doesn't appear to be the case and the side effects experienced from the drugs will vary by the individual. Common side effects include dizziness, drowsiness, and weight gain. It is classified as a controlled substance due to its potential for misuse or dependence. When comparing Lyrica gabapentin, it is important to note that both medications are used to treat similar conditions but have different potencies and side effect profiles. What is Gabapentin? More than half of the people in the study noted an improvement in pain relief when gabapentin was added. However, side effects from gabapentin were common. More than a third of the people in the study stopped taking gabapentin due to side effects. People who had side effects also didn’t experience as much improvement in their sciatica symptoms. Compare Gabapentin vs Pregabalin head-to-head with other drugs for uses, ratings, cost, side effects and interactions. A 2018 randomized clinical trial found that gabapentin provided more effective pain relief than pregabalin for those with chronic sciatica. Gabapentin was also found to have fewer adverse effects than pregabalin in these individuals. Lyrica is more likely than gabapentin to cause side effects such as dry mouth, constipation, swelling (edema), breast enlargement, or weight gain Gabapentin is more likely than Lyrica to cause side effects such as difficulty speaking, fever, an increased risk of viral infections, unusual eye movements, or jerky movements Lyrica was specially designed for treatment of neuropathic pain, therefore a risk of side-effects is very low. More often Lyrica side-effects arise in the central nervous system: dizziness, sleeplessness, tremor, incoordination, irritability, panic. Gabapentin side effects. Gabapentin can cause side effects such as: Lyrica side effects. Pregabalin should not be taken with some medications. So, make sure your doctor knows all the medicines
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