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Yes, Lyrica (pregabalin) can cause extreme drowsiness (somnolence) and may affect your ability to drive, operate machinery, or do other dangerous activities. This may lead to an injury or fall. In studies, up to 20% of children and 35% of adults experienced drowsiness as a side effect. Common side effects include dizziness, drowsiness, and fatigue. How Do Pregabalin and Gabapentin Work? Pregabalin and Gabapentin work by affecting nerve signals in the brain to reduce pain and prevent seizures. Both medications target calcium channels in nerve cells, slowing down excessive nerve activity. Pregabalin starts working faster because it is absorbed more quickly than gabapentin. The common side effects of Pregabalin include dry mouth, blurred vision, headache, weight gain, indigestion, and constipation. At the same time, the common side effects of Gabapentin include – shaking, diarrhea, dizziness, drowsiness, and weakness. Gabapentin is an anticonvulsant with pain-relieving effects that may be used to treat certain seizure disorders or relieve nerve pain. Common side effects include dizziness or drowsiness and it may more. Pregabalin is used in the treatment of nerve pain and also to prevent seizures. Both medications have common side effects, such as drowsiness, dizziness, and edema. But pregabalin is more likely to cause weight gain. More serious side effects, such as suicidal thoughts and behaviors, heart problems, or misuse, are more rare. Gabapentin can cause side effects such as: Pregabalin is also used to treat nerve pain. It's often prescribed to people whose nerve pain hasn't improved with other medicines. Pregabalin The most frequently reported side effect is headache for gabapentin (27 percent). Nausea (21 percent) is another frequent side effect. Gabapentin appears more helpful for treating fibromyalgia, but the side effects of the two drugs may be your deciding factor. On the other hand, there is more data on pregabalin and how to minimize the side A few studies have found that pregabalin has fewer side effects and may be more efficacious for neuropathic pain than gabapentin. Several studies reviewing conversion of gabapentin to pregabalin predict that a rough ratio for conversion is about 6:1 gabapentin to pregabalin. That said, differences in the occurrence rates of side effects for pregabalin and gabapentin may be less significant than available medical literature suggests. As of current, there are no convincing data to substantiate the idea that pregabalin is significantly more tolerable (i.e. causes fewer side effects) than gabapentin – or vice-versa. In addition to the mild side effects described above, serious side effects may occur in some people taking Lyrica or gabapentin. See the table below for a list of side effects that have been Side Effects: Lyrica vs Gabapentin Though the side effect profiles of both drugs are similar, some studies have found that Lyrica may have somewhat fewer of them. Dizziness and sleepiness are the most common side effects associated with both drugs, but more serious concerns such as suicidal ideation have also been reported. 1 Both drugs can also cause peripheral edema and nausea. 3,5 Gabapentin may also cause ataxia and diarrhea and additional side effects of pregabalin include headache, dry mouth, vision changes, and constipation. 3,5 Most side effects of Lyrica and gabapentin are mild and go away after using either medication for a few weeks. If the side effects bother or concern you or don’t go away, talk with your doctor. Gabapentin and pregabalin are similar drugs but differ in several distinct ways. The main differences are their indications—specific uses that the Food and Drug Administration (FDA) has approved them to treat—and their dosages. Pregabalin (Lyrica) and gabapentin (Neurontin and others) are drugs used to prevent seizures and to treat nerve pain associated with various conditions (shingles, diabetic neuropathy). Lyrica and gabapentin both cause similar side effects, including tremors, blurred or double vision, memory or concentration problems, dizziness, and drowsiness. Gabapentin is an anticonvulsant with pain-relieving effects that may be used to treat certain seizure disorders or relieve nerve pain. Common side effects include dizziness or drowsiness and it may In addition, Lyrica was initially thought to have less side effects than gabapentin since the drugs are so similar to one another but Lyrica is dosed in far less amounts. However, this doesn't appear to be the case and the side effects experienced from the drugs will vary by the individual. Side Effects: Pregabalin vs Gabapentin Comparison of Common Side Effects. The most common side effects of Lyrica include dizziness, drowsiness, headache, dry mouth, blurred vision, constipation, peripheral edema (swelling in the limbs), weight gain, and indigestion. Gabapentin is contraindicated in individuals who have hypersensitivity to this medication or its components, which can cause fever and other symptoms that could become severe. Pregabalin vs Gabapentin â What is the Difference? Pregabalin and gabapentin can both provide relief from pain and be effective ways to manage seizure disorders. Gabapentin Vs Pregabalin Side Effects. The side effects of both Gabapentin and Pregabalin are similar; however, some studies indicate that Pregabalin may have a lower risk of adverse effects. Two of the most common side effects of Gabapentin and Pregabalin include sleepiness and dizziness.
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