Gabapentin is a popular anticonvulsant medicine among humans and pets, especially for cats and dogs. Humans use the drug for mild and chronic pain and control seizure conditions. However, in cats, gabapentin is used for chronic musculoskeletal neuropathic pain and mild sedation in stressful situations such as vet visits, travel sickness etc. Knowing about the [] Dose: 300-800 mg PO tid; Start: 300 mg PO tid; Max: 3600 mg/day; Info: taper dose over >7 days to D/C renal dosing [adjust dose amount, frequency] CrCl 30-50: give 75% usual dose bid; CrCl 15-29: give 75% usual dose qd; CrCl 15: give 75% usual dose qod Child 6–11 years 10 mg/kg once daily (max. per dose 300 mg) on day 1, then 10 mg/kg twice daily (max. per dose 300 mg) on day 2, then 10 mg/kg 3 times a day (max. per dose 300 mg) on day 3; usual dose 25–35 mg/kg daily in 3 divided doses, some children may not tolerate daily increments; longer intervals (up to weekly) may be more appropriate, daily dose maximum to be given in 3 divided The established therapeutic dosing for gabapentin in neuropathic pain trials is 1800-3600 mg/day in 3 divided doses in patients with normal renal function. 3 This means the minimum effective dose is 600 mg 3 times a day. Renal adjustments are recommended in patients with CrCl below 60 mL/min. Adults, normal: 5 to 7 hours; increased half-life with decreased renal function; anuric adult patients: 132 hours; adults during hemodialysis: 3.8 hours. <3% In CrCl <30 mL/minute, half-life is approximately 52 hours (immediate release). .table_layout tbody td{ font-size:0.95em;} Usual Gabapentin Dosing (Adults) Usual initial gabapentin dose: 300mg q8h. Usual maintenance dose: 300-600mg q8h. Maximum dosage/day: 3600 mg Gabapentin Renal Dosing [>60 ml/min]: Give usual dosage : Dosage range: 400-1400mg/day (divided doses - Usually bid) : Dosage range: 200-700mg/day. : 100-300 mg/day. Use lower end of this range for CRCL Detailed Gabapentin dosage information for adults and children. Includes dosages for Restless Legs Syndrome, Epilepsy and Postherpetic Neuralgia; plus renal, liver and dialysis adjustments. Initial dose: 300 mg on day one, 300 mg twice daily on day two, and 300 mg three times daily on day three. Maintenance dose: 1800 mg per day, divided into three doses. Treatment duration varies. For adults, your gabapentin dosage varies depending on your medical conditions and which form you’re taking. The maximum dosage is 3,600 mg per day. For children, the dosage is based on age and body weight. Usual Adult Dose for Postherpetic Neuralgia: Initial dose: 300 mg orally on day one, 300 mg orally twice a day on day two, then 300 mg orally 3 times a day on day three. The dose may be titrated up as needed for pain relief to a daily dose of 1800 mg. Maintenance dose: 900 to 1800 mg orally in 3 divided doses. Gabapentin is used to help control partial seizures (convulsions) in the treatment of epilepsy. This medicine cannot cure epilepsy and will only work to control seizures for as long as you continue to take it. Gabapentin is also used to manage a condition called postherpetic neuralgia, which is pain that occurs after shingles. Usual Adult Dose for Restless Legs Syndrome: Gabapentin enacarbil available under the trade name Horizant: 600 mg orally once daily with food at about 5 PM Use: For the treatment of moderate-to-severe primary Restless Legs Syndrome (RLS) in adults. Usual Pediatric Dose for Epilepsy: Less than 3 years: Not recommended Child 6–11 years 10 mg/kg once daily (max. per dose 300 mg) on day 1, then 10 mg/kg twice daily (max. per dose 300 mg) on day 2, then 10 mg/kg 3 times a day (max. per dose 300 mg) on day 3; usual dose 25–35 mg/kg daily in 3 divided doses, some children may not tolerate daily increments; longer intervals (up to weekly) may be more appropriate, daily dose maximum to be given in 3 divided If you forget to take a dose of gabapentin, do not panic. Take it on the same day unless it is too close to the time of your next dose. If it is too close to the next dose, skip the missed dose. Resume the regular dosing schedule the following day. Do not take extra to make up for the missed dose. TABLE 1. NEURONTIN Dosage Based on Renal Function; TID = Three times a day; BID = Two times a day; QD = Single daily dose * For patients with creatinine clearance <15 mL/min, reduce daily dose in proportion to creatinine clearance (e.g., patients with a creatinine clearance of 7.5 mL/min should receive one-half the daily dose that patients with a creatinine clearance of 15 mL/min receive). Gabapentin capsules are usually taken orally three times a day (morning, afternoon, and evening) with plenty of water, with or without food. Gabapentin is available in 100 mg, 300 mg, and 400 mg capsules, and in 600 mg and 800 mg tablets. The third gabapentin formulation for PHN treatment is another extended-release product, Horizant. The starting dose is 600 mg in the morning for 3 days, increased to 600 mg twice daily on day 4 and thereafter. A daily dose of Horizant greater than 1,200 mg provided no additional benefit at the expense of side effects.³ Gabapentin Dosage for Pain (mg) Gabapentin Dosage for Seizures (mg) 💡 Tip; Up to 10 lbs: 50-100 mg every 12 hours: 50 mg every 8-12 hours: Use for small breeds like Chihuahuas or Pomeranians. 10-20 lbs: 100 mg every 8-12 hours: 100 mg every 8 hours: Great for dogs like Shih Tzus or Dachshunds. 20-50 lbs: 100-300 mg every 8-12 hours: 200 mg The usual dose for: adults and older children (aged 12 and over) is 900mg to 3,600mg a day, split into 3 doses younger children (aged 6 to 12) – varies depending on their weight The starting dose is 300 mg three times a day. The recommended maintenance dose of gabapentin capsules is 300 mg to 600 mg three times a day. Dosages up to 2,400 mg/day have been well tolerated in long-term clinical studies.
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