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The authors reviewed changes in body weight in 44 patients treated with Gabapentin (GPN) for a period of 12 or more months. All patients had a seizure disorder and the dose of GPN was increased aiming at complete seizure control or until side effects limited further increase. Twenty-eight patients w The treatment can also stimulate appetites and serotonin levels in some individuals, which again causes overeating—weight gain. Gabapentine and Weight Gain Studies Several studies evaluated the link between Gabapentin use and weight gain. While some studies came up empty on findings, others presented solid results demonstrating the possible Higher doses and longer treatment periods increase your risk of weight gain [11]. People who take Gabapentin might gain about 5 pounds after just 6 weeks of use [12]. Weight gain affected 3% of patients over 12 years old with epilepsy, compared to 2% who took a placebo [12]. The most common gabapentin (Neurontin) side effects are dizziness and drowsiness. This may affect your ability to drive or perform other activities. Other gabapentin side effects include edema (fluid buildup), weight gain, and eye problems, but these aren’t as common. Rare but serious gabapentin side effects include mood changes in children. Weight gain due to gabapentin is different and depends on the dose and duration of its use. According to one research study, gabapentin was associated with a weight gain of about 5.5 pounds after 1.5 months of use. weight gain; swelling of the hands, feet, or ankles; back or joint pain; flulike symptoms such as fever or body aches. Rare but serious side effects. Rare but serious side effects of gabapentin include: rash, itching, or yellowing of the skin; swelling of the face and throat, a condition called angioedema; problems speaking or swallowing Weight gain Gabapentin can make you hungrier, so it can be hard to stop yourself putting on weight. Try to eat a healthy, balanced diet without increasing your portion sizes. One side effect that’s more common with pregabalin is weight gain. This side effect doesn’t appear to be linked to fluid buildup, but it’s something to pay attention to if you’re starting pregabalin. Weight gain doesn’t seem to be as common with gabapentin. Serious side effects weight gain; Managing side effects 13. Gidal BE, Maly MM, Nemire RE, Haley K (1995) "Weight gain and gabapentin therapy." Ann Pharmacother, 29, p. 1048. 14. Lasso Gabapentin can cause weight gain, but this side effect is usually rare. People may gain weight while taking gabapentin because the drug increases their appetite and causes water retention, mainly in the arms, hands, legs, and feet. Gabapentin water retention is another example of how the body can change when a medication is taken. Yes, it can, although weight gain is rare with gabapentin and more commonly associated with higher dosages. Even with a lower dose like 300mg, some people may experience an increase in appetite or fluid retention, leading to weight gain. While weight gain is a rare side effect of gabapentin, it still happens. In fact, weight gain from gabapentin only occurs in around 2% of patients. 1 However, weight gain is not to be confused with peripheral edema, which is a swelling in the legs caused by a build-up of fluids. This occurs in around 8% of patients taking gabapentin. 1 Weight Gain: Weight gain is a less common side effect of gabapentin but may occur in some individuals. Some users have experienced weight gain, which can be attributed to factors like increased appetite and fluid retention. Gabapentin can potentially cause weight gain, usually due to peripheral edema, a common side effect. This refers to swelling in the ankles and feet due to fluid retention. Weight gain from gabapentin unrelated to peripheral edema isn’t very common. To avoid weight gain from gabapentin, make sure you’re taking the dose your prescriber Patients who have been prescribed gabapentin are often concerned about weight gain as a side effect. However, they should note, weight gain is a very rare side effect, observed in less than 5% of patients. In cases where weight gain does occur, it is typically a result of an increased appetite or reduced exercise caused by the drug. Yes, weight gain is a possible side effect for gabapentin (brand name Neurontin). The incidence of weight gain with gabapentin varies by product: Immediate release gabapentin: 2-3%; Extended release gabapentin (e.g. Gralise, Horizant): 1.9-5% Gabapentin may cause weight gain in some people, but it is not a common side effect. Learn how gabapentin affects appetite, fluid retention and exercise, and how to avoid weight gain with healthy habits. One review article looking at weight gain from medications found an average weight gain of almost 5 pounds after just 1.5 months on gabapentin. Another study looking at weight changes after a longer course of the medication found that over half of participants gained more than 5% of their baseline body weight, with 23% of participants gaining Clinical trials suggest that less than 3% of all Gabapentin users will gain weight – this means that only a small number of people 3/100 will gain weight. Some speculate that more people gain weight than what is reported by the drug company and/or clinical documentation.
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